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Chemical Structure| 34306-42-8 Chemical Structure| 34306-42-8
Chemical Structure| 34306-42-8

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CAS No.: 34306-42-8

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Boc-Abu-OH is a protected α-aminobutyric acid derivative with the amino group protected by tert-butoxycarbonyl (Boc), suitable for peptide synthesis.

Synonyms: Boc-L-2-aminobutanoic acid; Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-; (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid

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Product Details of Boc-Abu-OH

CAS No. :34306-42-8
Formula : C9H17NO4
M.W : 203.24
SMILES Code : CC[C@H](NC(OC(C)(C)C)=O)C(O)=O
Synonyms :
Boc-L-2-aminobutanoic acid; Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-; (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid
MDL No. :MFCD00037267
InChI Key :PNFVIPIQXAIUAY-LURJTMIESA-N
Pubchem ID :2755934

Safety of Boc-Abu-OH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Boc-Abu-OH

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 34306-42-8 ]
  • Downstream synthetic route of [ 34306-42-8 ]

[ 34306-42-8 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 67-56-1 ]
  • [ 34306-42-8 ]
  • [ 7682-18-0 ]
YieldReaction ConditionsOperation in experiment
100% at 0 - 20℃; 10.0 g (49.2 mmol) BOC-L-2-aminobutyric acid was dissolved in 100 ml of methanol and 6 ml (82.2 mmol) thionyl chloride were added dropwise at 0° C. The solution was stirred for 14 h at ambient temperature and then evaporated down in vacuo.Yield: 7.6 g (101percent) 2-a.ES-MS (M+H)+=118
References: [1] Patent: US2010/144681, 2010, A1, . Location in patent: Page/Page column 67.
 

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