成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart Sign in  
Chemical Structure| 29022-11-5 Chemical Structure| 29022-11-5
Chemical Structure| 29022-11-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

{[proInfo.proName]}

CAS No.: 29022-11-5

,{[proInfo.pro_purity]}

Fmoc-Gly-OH is a protected glycine derivative with the amino group protected by 9-fluorenylmethoxycarbonyl (Fmoc), suitable for peptide synthesis.

Synonyms: Fmoc glycine; N-(9-Fluorenylmethoxycarbonyl)glycine; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support Online Technical Q&A
Product Citations

Product Citations

Kristina Westerlund ; Maryam Oroujeni ; Maxime Gestin ; Jacob Clinton ; Alia Hani Rosly ; Hanna Tano , et al.

Abstract: Affibody-mediated PNA-based pretargeting shows promise for HER2-expressing tumor radiotherapy. In our recent study, a 15-mer ZHER2:342-HP15 affibody-PNA conjugate, in combination with a shorter 9-mer [177Lu]Lu-HP16 effector , emerged as the most effective pretargeting strategy. It offered a superior tumor-to-kidney uptake ratio and more efficient tumor targeting compared to longer radiolabeled effector probes containing 12 or 15 complementary bases. To enhance the production efficiency of our pretargeting system, we here introduce even shorter 6-, 7-, and 8-mer secondary probes, designated as HP19, HP21, and HP20, respectively. We also explore the replacement of the original 15-mer Z-HP15 primary with shorter 12-mer Z-HP12 and 9-mer Z-HP9 alternatives. This extended panel of shorter PNA-based probes was synthesized using automated microwave-assisted methods and biophysically screened in vitro to identify shorter combinations with the most effective binding properties. In a mouse xenograft model, we evaluated the biodistribution of these probes, comparing them to the Z-HP15:[177Lu]Lu-HP16 combination. Tumor-to-kidney ratios at 4 and 144 h postinjection of the secondary showed no significant differences among the Z-HP9:[177Lu]Lu-HP16, Z-HP9:[177Lu]Lu-HP20, and the Z-HP15:[177Lu]Lu-HP16 pairs. Importantly, tumor uptake significantly exceeded, by several hundred-fold, that of most normal tissues, with kidney uptake being the critical organ for radiation therapy. This suggests that using a shorter 9-mer primary , Z-HP9, in combination with 9-mer HP16 or 8-mer HP20 secondary probes effectively targets tumors while minimizing the dose-limiting kidney uptake of radionuclide. In conclusion, the Z-HP9:HP16 and Z-HP9:HP20 combinations offer good prospects for both cost-effective production and efficient in vivo pretargeting of HER2-expressing tumors.

Keywords: affibody ; pretargeting ; nucleic acid ; radiotherapy

Purchased from AmBeed:

Alternative Products

Product Details of Fmoc-Gly-OH

CAS No. :29022-11-5
Formula : C17H15NO4
M.W : 297.31
SMILES Code : O=C(O)CNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Synonyms :
Fmoc glycine; N-(9-Fluorenylmethoxycarbonyl)glycine; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid
MDL No. :MFCD00037140
InChI Key :NDKDFTQNXLHCGO-UHFFFAOYSA-N
Pubchem ID :93124

Safety of Fmoc-Gly-OH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338
 

Historical Records

Technical Information

Categories