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Chemical Structure| 25451-15-4 Chemical Structure| 25451-15-4
Chemical Structure| 25451-15-4

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CAS No.: 25451-15-4

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Felbamate is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .

Synonyms: W-554; ADD-03055; Taloxa

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Product Details of Felbamate

CAS No. :25451-15-4
Formula : C11H14N2O4
M.W : 238.24
SMILES Code : NC(OCC(C1=CC=CC=C1)COC(N)=O)=O
Synonyms :
W-554; ADD-03055; Taloxa
InChI Key :WKGXYQFOCVYPAC-UHFFFAOYSA-N
Pubchem ID :3331

Safety of Felbamate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • NMDA receptor

    NMDAR, IC50:1.8 mM

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00404248 Brain and Central Nervous Syst... More >>em Tumors Less << Phase 1 Phase 2 Completed - United States, Alabama ... More >> UAB Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3410 United States, Florida H. Lee Moffitt Cancer Center and Research Institute at University of South Florida Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Michigan Josephine Ford Cancer Center at Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, North Carolina Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Less <<
NCT00404248 - Completed - -
NCT01390909 - Completed - -
NCT00552526 Epilepsy Ment... More >>al Retardation Less << Phase 4 Unknown December 2013 Norway ... More >> SSE, Nevrological dep. , Rikshospitalet University hospital Oslo, Norway Less <<
NCT00034229 Bipolar Disorder PHASE2 COMPLETED 2025-03-06 National Institute of Mental H... More >>ealth (NIMH), Bethesda, Maryland, 20892, United States Less <<
NCT01390909 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.20mL

0.84mL

0.42mL

20.99mL

4.20mL

2.10mL

41.97mL

8.39mL

4.20mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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