成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart Sign in  
Chemical Structure| 25194-67-6 Chemical Structure| 25194-67-6

Structure of 25194-67-6

Chemical Structure| 25194-67-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

{[proInfo.proName]}

CAS No.: 25194-67-6

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 25194-67-6 ]

CAS No. :25194-67-6
Formula : C11H10N2O
M.W : 186.21
SMILES Code : NC1=CC=C(OC2=CC=CC=C2)N=C1
MDL No. :MFCD01692449
InChI Key :DETKIRMPBJPJRQ-UHFFFAOYSA-N
Pubchem ID :212856

Safety of [ 25194-67-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 25194-67-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 25194-67-6 ]

[ 25194-67-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 25194-67-6 ]
  • [ 1171919-75-7 ]
  • tert-butyl (3R)-3-[(2-sulfanylacetyl)amino]piperidine-1-carboxylate [ No CAS ]
  • [ 530-62-1 ]
  • (R)-tert-butyl 3-(4-oxo-5-(6-phenoxypyridin-3-yl)-4,5-dihydro-3H-1-thia-3,5,8-triazaacenaphthylene-2-carboxamido)piperidine-1-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
57.7% To a 2-5 mL Biotage microwave vial containing a stir bar were added 6-phenoxypyridin-3 -amine (182 mg, 0.0.980 mmol), 2- chloro-4-iodonicotinonitrile (256 mg, 0.971 mmol), Pd(OAc)2 (4.7 mg, 0.021 mmol), DPEPhos (15.6 mg, 0.029 mmol), and CS2CO3(446 mg, 1.37 mmol). The vial was sealed, treated with dioxane (1.95 mL), evacuated and flushed with argon 4X, and stirred at 150 C under argon for 30 min. The reaction was cooled to rt, treated with fert-butyl (3R)-3-[(2- sulfanylacetyl)amino]piperidine-l -carboxylate (Intermediate 22) (2.0 mL, 0.49 M, 0.98 mmol) via syringe, evacuated and flushed with argon 4X, and stirred at 150 C for 15 min. The reaction was cooled to rt, treated with solid CDI (628 mg, 3.87 mmol) in one portion, resealed, and evacuated and flushed with argon 4X, and stirred at 150 C for 15 min. The reaction was then diluted with EtOAc (10 mL), and washed with 0.5 M citric acid/brine solution (2 X 8 mL) and 2 M K2CO3(1 X 5 mL). The organic phase was dried over anhydrous Na2S04, filtered, and concentrated to dryness. The residue was dissolved in DCM (5 mL) and purified by flash column chromatography to yield the title compound as an orange-yellow foam (328 mg, 57.7% yield).
57.7% To a 2-5 mL Biotage microwave vial containing a stir bar were added 6-phenoxypyridin-3-amine (182 mg, 0.0.980 mmol) , <strong>[1171919-75-7]2-chloro-4-iodonicotinonitrile</strong> (256 mg, 0.971 mmol) , Pd (OAc) 2 (4.7 mg, 0.021 mmol) , DPEPhos (15.6 mg, 0.029 mmol) , and Cs2CO3(446 mg, 1.37 mmol) . The vial was sealed, treated with dioxane (1.95 mL) , evacuated and flushed with argon 4X, and stirred at 150 under argon for 30 min. The reaction was cooled to rt, treated with tert-butyl (3R) -3- [ (2-sulfanylacetyl) amino] piperidine-1-carboxylate (Intermediate 22) (2.0 mL, 0.49 M, 0.98 mmol) via syringe, evacuated and flushed with argon 4X, and stirred at 150 for 15 min. The reaction was cooled to rt, treated with solid CDI (628 mg, 3.87 mmol) in one portion, resealed, and evacuated and flushed with argon 4X, and stirred at 150 for 15 min. The reaction was then diluted with EtOAc (10 mL) , and washed with 0.5 M citric acid/brine solution (2 X 8 mL) and 2 M K2CO3(1 X 5 mL) . The organic phase was dried over anhydrous Na2SO4, filtered, and concentrated to dryness. The residue was dissolved in DCM (5 mL) and purified by flash column chromatography to yield the title compound as an orange-yellow foam (328 mg, 57.7yield) .
 

Related Products

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 25194-67-6 ]

Aryls

Chemical Structure| 219865-99-3

A500443 [219865-99-3]

6-(4-Methoxyphenoxy)pyridin-3-amine

Similarity: 1.00

Chemical Structure| 305801-13-2

A291404 [305801-13-2]

6-(3-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.98

Chemical Structure| 83414-50-0

A319232 [83414-50-0]

6-(Naphthalen-2-yloxy)pyridin-3-amine

Similarity: 0.96

Chemical Structure| 305801-17-6

A609195 [305801-17-6]

6-(2-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.96

Ethers

Chemical Structure| 219865-99-3

A500443 [219865-99-3]

6-(4-Methoxyphenoxy)pyridin-3-amine

Similarity: 1.00

Chemical Structure| 305801-13-2

A291404 [305801-13-2]

6-(3-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.98

Chemical Structure| 83414-50-0

A319232 [83414-50-0]

6-(Naphthalen-2-yloxy)pyridin-3-amine

Similarity: 0.96

Chemical Structure| 305801-17-6

A609195 [305801-17-6]

6-(2-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.96

Chemical Structure| 99185-50-9

A588872 [99185-50-9]

6-(Pyridin-3-yloxy)pyridin-3-amine

Similarity: 0.94

Amines

Chemical Structure| 219865-99-3

A500443 [219865-99-3]

6-(4-Methoxyphenoxy)pyridin-3-amine

Similarity: 1.00

Chemical Structure| 305801-13-2

A291404 [305801-13-2]

6-(3-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.98

Chemical Structure| 83414-50-0

A319232 [83414-50-0]

6-(Naphthalen-2-yloxy)pyridin-3-amine

Similarity: 0.96

Chemical Structure| 305801-17-6

A609195 [305801-17-6]

6-(2-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.96

Chemical Structure| 99185-50-9

A588872 [99185-50-9]

6-(Pyridin-3-yloxy)pyridin-3-amine

Similarity: 0.94

Related Parent Nucleus of
[ 25194-67-6 ]

Pyridines

Chemical Structure| 219865-99-3

A500443 [219865-99-3]

6-(4-Methoxyphenoxy)pyridin-3-amine

Similarity: 1.00

Chemical Structure| 305801-13-2

A291404 [305801-13-2]

6-(3-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.98

Chemical Structure| 83414-50-0

A319232 [83414-50-0]

6-(Naphthalen-2-yloxy)pyridin-3-amine

Similarity: 0.96

Chemical Structure| 305801-17-6

A609195 [305801-17-6]

6-(2-Methoxyphenoxy)pyridin-3-amine

Similarity: 0.96

Chemical Structure| 99185-50-9

A588872 [99185-50-9]

6-(Pyridin-3-yloxy)pyridin-3-amine

Similarity: 0.94