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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 1978-37-6 Chemical Structure| 1978-37-6
Chemical Structure| 1978-37-6

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CAS No.: 1978-37-6

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Product Details of [ 1978-37-6 ]

CAS No. :1978-37-6
Formula : C7H8FN
M.W : 125.14
SMILES Code : CNC1=CC=CC(F)=C1
MDL No. :MFCD02683095
InChI Key :FHYDHJXZZQCXOX-UHFFFAOYSA-N
Pubchem ID :2759011

Safety of [ 1978-37-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H301-H318
Precautionary Statements:P280-P301+P310-P305+P351+P338
Class:3(6.1)
UN#:1992
Packing Group:

Application In Synthesis of [ 1978-37-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1978-37-6 ]

[ 1978-37-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 129112-65-8 ]
  • [ 1978-37-6 ]
  • 2-chloro-N-(3-fluorophenyl)-N-methyl-7-nitroquinazolin-4-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium hydride; In N,N-dimethyl-formamide; at 20℃; for 1.0h; To a solution of <strong>[129112-65-8]2,4-dichloro-7-nitroquinazoline</strong> (100 mg, 0.41 mmol) in DMF (2.1 mL) were added 3-fluoro-N-methylaniline (51.3 mg, 0.41 mmol) and sodium hydride (9.83 mg, 0.41 mmol), and the mixture was stirred for 1 h at RT. The reaction mixture was diluted with AcOEt, washed successively with water and brine. The organic layer was concentrated in vacuo. The residue was used for the next step without further purification. LCMS(m/z) 332.8 [M+H]+.
 

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