[ CAS No. 19346-43-1 ] {[proInfo.proName]}

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2D 3D

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Quality Control of [ 19346-43-1 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 19346-43-1 ]

SDS Specification

Alternatived Products of [ 19346-43-1 ]

Product Details of [ 19346-43-1 ]

CAS No. :	19346-43-1	MDL No. :	MFCD04112526
Formula :	C₆H₅FN₂O₂	Boiling Point :	No data available
Linear Structure Formula :	-	InChI Key :	AUHFWLUBEJKXLN-UHFFFAOYSA-N
M.W :	156.11	Pubchem ID :	12408182
Synonyms :

Calculated chemistry of [ 19346-43-1 ] Expand+

Physicochemical Properties

Num. heavy atoms :	11
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.17
Num. rotatable bonds :	1
Num. H-bond acceptors :	4.0
Num. H-bond donors :	0.0
Molar Refractivity :	37.98
TPSA :	58.71 ?2

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.2 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.1
Log Po/w (XLOGP3) :	1.48
Log Po/w (WLOGP) :	1.86
Log Po/w (MLOGP) :	0.04
Log Po/w (SILICOS-IT) :	0.09
Consensus Log Po/w :	0.91

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-2.08
Solubility :	1.3 mg/ml ; 0.00836 mol/l
Class :	Soluble
Log S (Ali) :	-2.32
Solubility :	0.747 mg/ml ; 0.00479 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-2.06
Solubility :	1.37 mg/ml ; 0.00875 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	3.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.98

Safety of [ 19346-43-1 ]

Signal Word:	Warning	Class:
Precautionary Statements:	P261-P280-P305+P351+P338	UN#:
Hazard Statements:	H302-H315-H319-H332-H335	Packing Group:
GHS Pictogram:

Application In Synthesis of [ 19346-43-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 19346-43-1 ]
Downstream synthetic route of [ 19346-43-1 ]

[ 19346-43-1 ] Synthesis Path-Upstream 1~1

1
[ 19346-43-1 ]
[ 173435-32-0 ]

Reference： [1] Patent: US5494887, 1996, A,
[2] Patent: US5571775, 1996, A,
[3] Patent: US5602075, 1997, A,
[4] Patent: US5614469, 1997, A,

[ 19346-43-1 ] Synthesis Path-Downstream 1~16

2
[ 19346-43-1 ]
[ 173435-32-0 ]

Yield	Reaction Conditions	Operation in experiment
	With acetic acid;palladium; In ethyl acetate;	26. Preparation of 3-Amino-2-fluoro-4-methylpyridine To a solution of 10.1 g (65 mmol) of <strong>[19346-43-1]2-fluoro-4-methyl-3-nitropyridine</strong> in 200 mL of ethyl acetate was added 25 g (0.40 mol) of acetic acid and 0.8 g of 5 percent palladium on carbon catalyst. This mixture was shaken under 50 psig (pounds per square inch gauge) (2400 kiloPascals) pressure of hydrogen for 18 hours, was filtered, and was concentrated by evaporation under reduced pressure to obtain an oil. This oil was partitioned between dilute aqueous sodium bicarbonate and ether. The organic phase was recovered, dried over magnesium sulfate, and filtered. The filtrate was concentrated by evaporation under reduced pressure and the residue was purified by column chromatography to obtain 7.2 g (88 percent of theory) of the title compound as a colorless solid melting at 63-64 C. Nuclear Magnetic Resonance Spectrum (200 MHz (megaHertz), CDCl3): 1 H: 7.4 (d, 1H, J=5.0); 6.8 (d, 1H, J=5.0); 3.7 (br, 2H); 2.1 (s, 3H); 13 C: 152.6 (d, J=229); 134.1 (d, J=8.6); 133.8 (d, J=14.5); 128.1 (d, J=27.1); 123.3, 16.4 (d, J=4.1).
	With acetic acid;palladium; In ethyl acetate;	41. Preparation of 3-Amino-2-fluoro-4-methylpyridine To a solution of 10.1 g (65 mmol) of <strong>[19346-43-1]2-fluoro-4-methyl-3-nitropyridine</strong> in 200 mL of ethyl acetate was added 25 g (0.40 mol) of acetic acid and 0.8 g of 5 percent palladium on carbon catalyst. This mixture was shaken under 50 psig (pounds per square inch gauge, 2400 kiloPascals) pressure of hydrogen for 18 hours, was filtered, and was concentrated by evaporation under reduced pressure to obtain an oil. This oil was partitioned between dilute aqueous sodium bicarbonate and ether. The organic phase was separated, dried over magnesium sulfate, and filtered. The filtrate was concentrated by evaporation under reduced pressure and the residue was purified by column chromatography to obtain 7.2 g (88 percent of theory) of the title compound as a colorless solid melting at 63-64 C. Elemental Analysis C6 H7 FN2 Calc.: %C, 57.1; %H, 5.59; %N, 22.2 Found: %C, 57.2; %H, 5.73; %N, 22.1 1 H NMR CDCl3: 7.4 (d, 1H, J=5.0); 6.8 (d, 1H, J=5.0); 3.7 (br, 2H); 2.1 (s, 3H); 13 C NMR CDCl3: 152.6 (d, J=229); 134.1 (d, J=8.6); 133.8 (d, J=14.5); 128.1 (d, J=27.1); 123.3, 16.4 (d, J=4.1).
	With acetic acid;palladium; In ethyl acetate;	18. Preparation of 3-Amino-2-fluoro-4-methylpyridine To a solution of 10.1 g (65 mmol) of <strong>[19346-43-1]2-fluoro-4-methyl-3-nitropyridine</strong> in 200 mL of ethyl acetate was added 25 g (0.40 mol) of acetic acid and 0.8 g of 5 percent palladium on carbon catalyst. This mixture was shaken under 50 psig (pounds per square inch gauge) (2400 kiloPascals) pressure of hydrogen for 18 hours, was filtered, and was concentrated by evaporation under reduced pressure to obtain an oil. This oil was partitioned between dilute aqueous sodium bicarbonate and ether. The organic phase was separated, dried over magnesium sulfate, and filtered. The filtrate was concentrated by evaporation under reduced pressure and the residue was purified by column chromatography to obtain 7.2 g (88 percent of theory) of the title compound as a colorless solid, melting at 63-64 C. Nuclear Magnetic Resonance Spectrum (200 MHz (megaHertz), CDC13): 1 H: 7.4 (d, 1H, J=5.0); 6.8 (d, 1H, J=5.0); 3.7 (br, 2H); 2.1 (s, 3H); 13 C: 152.6 (d, J=229); 134.1 (d, J=8.6); 133.8 (d, J=14.5); 128.1 (d, J=27.1); 123.3, 16.4 (d, J=4.1).

With acetic acid;palladium; In ethyl acetate;

1. Preparation of 3-Amino-2-fluoro-4-methylpyridine To a solution of 10.1 g (grams) (65 mmol (millimole)) of [19346-43-1]2-fluoro-4-methyl-3-nitropyridine in 200 mL (milliliter) of ethyl acetate was added 25 g (0.40 mol) of acetic acid and 0.8 g of 5 percent palladium on carbon catalyst. This mixture was shaken under 50 psig (pounds per square inch gauge, 2400 kiloPascals) pressure of hydrogen for 18 hours, was filtered, and was concentrated by evaporation under reduced pressure to obtain an oil. This oil was partitioned between dilute aqueous sodium bicarbonate and ether. The organic phase was separated, dried over magnesium sulfate, and filtered. The filtrate was concentrated by evaporation under reduced pressure and the residue was purified by column chromatography to obtain 7.2 g (88 percent of theory) of the title compound as a colorless solid melting at 63-64 C. Elemental Analysis C6 H7 FN2 Calc.: %C, 57.1; %H, 5.59; %N, 22.2 Found: %C, 57.2; %H, 5.73; %N, 22.1 1 H NMR (nuclear magnetic resonance spectrum (200 megahertz)) CDCl3:7.4 (d, 1H, J=5.0); 6.8 (d, 1H, J=5.0); 3.7 (br, 2H); 2.1 (s, 3H); 13C NMR CDCl3:152.6 (d, J=229); 134.1 (d, J=8.6); 133.8 (d, J=14.5); 128.1 (d, J=27.1); 123.3, 16.4 (d, J=4.1).

Reference： [1]Patent: US5494887,1996,A
[2]Patent: US5571775,1996,A
[3]Patent: US5602075,1997,A
[4]Patent: US5614469,1997,A

3
[ 19346-43-1 ]
[ 21901-19-9 ]
[ 640278-72-4 ]

Yield	Reaction Conditions	Operation in experiment
53.1%	In propan-1-ol; for 0.5h;Heating;	General procedure: The dimethyl derivatives (4,4?, 5,5? or 6,6?) of 3,3?-dinitro-2,2?-azobipyridine were synthesized from the respective hydrazo-derivatives obtained previously from 3-nitro-4(or 5 or 6)-methyl-2-hydrazine-pyridine, respectively. Syntheses of these hydrazo derivatives were very similar to the synthesis of 3,3?-dinitro-2,2?-hydrazobipyridine. Instead of ethanol n-propanol was used and its mixtures were heated at boiling temperature for 30 min in the water bath. 2.52 g (0.015 mol) of 3-nitro-4(or 5 or 6)-methyl-2-hydrazine-pyridine were used to synthesis. The synthesized red-brown needle-like crystals of 4,4?-dimethyl-3,3?-dinitro-2,2?-hydrazobipyridine melt with decomposition at 255C. The yield was 53.1%. The synthesized brown needle-like crystals of 5,5?-dimethyl-3,3?-dinitro-2,2?-hydrazobipyridine melt with decomposition at 285C. The yield was 54.0%. The synthesized dark-brown needle-like crystals of 6,6?-dimethyl-3,3?-dinitro-2,2?-hydrazobipyridine melt with decomposition at 275C. The yield was 51.0%. 1 g of the obtained in this way 4,4?(or 5,5? or 6,6?)-3,3?-dinitro-2,2?-hydrazobipyridine was used to obtain respective azo derivatives in the same way as 3NAP. The synthesized orange needle-like crystals of 4,4?-dimethyl-3,3?-dinitro-2,2?-azobipyridine (4M3NAP) melt with decomposition at 260C. The yield was 74.2%. The synthesized orange needle-like crystals of 5,5?-dimethyl-3,3?-dinitro-2,2?-azobipyridine (5M3NAP) melt with decomposition at 256C. The yield was 77.1%. The synthesized orange powder of 6,6?-dimethyl-3,3?-dinitro-2,2?-azobipyridine (6M3NAP) melt with decomposition at 206C. The yield was 80.3% [51,52,54].
	With sodium hydrogencarbonate; In propan-1-ol; water; for 0.5h;Reflux;	2.52 g (0.015 mol) of 2-hydrazine-4-methyl-3-nitropyridine was added to 40 cm3 of n-propanol, 5 cm3 of water, 1 g of sodium bicarbonate and 2.34 g (0.015 mol of <strong>[19346-43-1]2-fluoro-4-methyl-3-nitro-pyridine</strong>. The mixture was heated for 30 min under reflux on a water bath. The mixture changed its color to purple. Then it was evaporated to dryness under reduced pressure and the dry residue was added to 150 cm3 of water, acidified with dilute hydrochloric acid and allowed to stand at room temperature for 12 h. Then the reaction product was filtered and recrystallized with activated carbon. An insoluble product in a form of red-brown needle-shaped crystals was filtered off, dried and re-crystallized twice from ethanol. It was sparingly soluble in water and organic solvents, soluble in glacial acetic acid. The melting point of MNHP was determined giving the value 255 C. More details (e.g. the yield and the chemical analysis) of the synthesis can be found in our publications [16,19].

Reference： [1]Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2014,vol. 127,p. 370 - 380
[2]Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2014,vol. 127,p. 303 - 309

4
[ 19346-43-1 ]
[ 21901-19-9 ]
[ 795306-06-8 ]

Reference： [1]Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2014,vol. 127,p. 370 - 380

5
7-chloro-1H-indazol-5-amine [ No CAS ]
[ 19346-43-1 ]
7-chloro-N-(4-methyl-3-nitropyridin-2-yl)-1H-indazol-5-amine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
21%	In N,N-dimethyl-formamide; at 150.0℃; for 2.0h;Microwave irradiation;	A solution of 7-chloro-IH-indazol-5-arnine (100 mg, 0.597 mmol) and <strong>[19346-43-1]2-fluoro-4-methyl-3-nitropyridine</strong> (93 rng, 0597mmol) in DMF (1.5 rnL) was reacted in the microwave at 150 0Q for 2 h. The reaction was diluted with water and EtOAc and extracted with EtOAc. The combined organic layers were dried (Na2SO4), filtered, and concentrated in vaeuo. Purification (FCC, Si02, 0-70-100% EtOAc in hexanes) afforded the title compound (38 rng, 21%). ?H NMR (400 MHz, CDC13) b S. 20 (s, 1Ff), 8.19 (d, J:::: 4.8 Hz, 1H), 8.09 (s, 1H), 783 (d, J 1.7 Hz, 1Ff), 7.56 (d, J == 1.7 Hz, IH), 6.72-6.67(m, iH, 2.60 (s, 3H.

Reference： [1]Patent: WO2016/176460,2016,A1 .Location in patent: Page/Page column 223

6
[ 19346-43-1 ]
3-(1H-indazol-5-yl)-7-methyl-2-(trifluoromethyl)imidazo[4,5-b]pyridine [ No CAS ]
3-(7-chloro-1H-indazol-5-yl)-7-methyl-2-(trifluoromethyl)imidazo[4,5-b]pyridine [ No CAS ]

Reference： [1]Patent: WO2016/176460,2016,A1

7
[ 19346-43-1 ]
N2-(7-chloro-1H-indazol-5-yl)-4-methylpyridine-2,3-diamine [ No CAS ]
N2-(1H-indazol-5-yl)-4-methylpyridine-2,3-diamine [ No CAS ]

Reference： [1]Patent: WO2016/176460,2016,A1

8
[ 19346-43-1 ]
C₁₃H₁₅N₃ [ No CAS ]

Reference： [1]Patent: WO2019/28308,2019,A1

9
[ 19346-43-1 ]
C₁₈H₂₃N₃O [ No CAS ]

Reference： [1]Patent: WO2019/28308,2019,A1

10
[ 19346-43-1 ]
C₁₈H₂₁N₃ [ No CAS ]

Reference： [1]Patent: WO2019/28308,2019,A1

11
[ 19346-43-1 ]
[ 100-46-9 ]
C₁₃H₁₃N₃O₂ [ No CAS ]

Reference： [1]Patent: WO2019/28308,2019,A1 .Location in patent: Page/Page column 50

12
[ 19346-43-1 ]
[ 110-76-9 ]
N-(2-ethoxyethyl)-4-methyl-3-nitropyridin-2-amine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
1.52 g	With potassium carbonate; In N,N-dimethyl-formamide; at 20.0℃;	To 2-ethoxyethan-1 -amine (0.659 g, 7.40 mmol) in DMF (10 mL) were added 2-fluoro-4- methyl-3-nitropyridine (1 .05g, 6.73 mmol) and K2C03 (1 .022 g, 7.40 mmol), and the reaction mixture was stirred at room temperature overnight. The reaction was diluted with water (30 mL) and extracted with EtOAc (4 x 20 mL). The organic extracts were combined and washed with brine, dried over MgS04, filtered, and concentrated. Purification by chromatography on silica gel (0 to 30% EtOAc/hexanes) afforded N-(2-ethoxyethyl)-4- methyl-3-nitropyridin-2-amine (1 .52 g) as an orange color oil. LC-MS (ES) m/z = 226 [M+H]+. NMR (400 MHz, DMSO-c/6): 5 1 .1 1 (t, J =7.0 Hz, 3H), 2.39 (s, 3H), 3.46 (q, J = 6.8 Hz, 2H), 3.50 - 3.55 (m, 2H), 3.56 - 3.63 (m, 2H), 6.64 (d, J = 4.8 Hz, 1 H), 7.54 (t, J = 5.1 Hz, 1 H), 8.16 (d, J = 4.8 Hz, 1 H).

Reference： [1]Patent: WO2019/49061,2019,A1 .Location in patent: Page/Page column 299; 300

13
[ 19346-43-1 ]
5-bromo-N-(2-ethoxyethyl)-4-methyl-3-nitropyridin-2-amine [ No CAS ]

Reference： [1]Patent: WO2019/49061,2019,A1

14
[ 19346-43-1 ]
6-bromo-2-(6-((2S,5S)-2,5-dimethylpyrrolidin-1-yl)pyridin-3-yl)-3-(2-ethoxyethyl)-7-methyl-3H-imidazo[4,5-b]pyridine [ No CAS ]

Reference： [1]Patent: WO2019/49061,2019,A1

15
[ 19346-43-1 ]
2-(6-((2S,5S)-2,5-dimethylpyrrolidin-1-yl)pyridin-3-yl)-3-(2-ethoxyethyl)-7-methyl-3H-imidazo[4,5-b]pyridine [ No CAS ]

Reference： [1]Patent: WO2019/49061,2019,A1

16
[ 19346-43-1 ]
(2-(6-((2S,5S)-2,5-dimethylpyrrolidin-1-yl)pyridin-3-yl)-3-(2-ethoxyethyl)-7-methyl-3H-imidazo[4,5-b]pyridin-6-yl)boronic acid [ No CAS ]

Reference： [1]Patent: WO2019/49061,2019,A1

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P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

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[ CAS No. 19346-43-1 ] {[proInfo.proName]}

Quality Control of [ 19346-43-1 ]

Related Doc. of [ 19346-43-1 ]

Product Details of [ 19346-43-1 ]

Calculated chemistry of [ 19346-43-1 ] Expand+

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 19346-43-1 ]

Application In Synthesis of [ 19346-43-1 ]

[ 19346-43-1 ] Synthesis Path-Upstream 1~1

[ 19346-43-1 ] Synthesis Path-Downstream 1~16

Technical Information

Related Functional Groups of [ 19346-43-1 ]

Fluorinated Building Blocks

Nitroes

Related Parent Nucleus of [ 19346-43-1 ]

Pyridines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

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[ 19346-43-1 ]

Related Parent Nucleus of
[ 19346-43-1 ]