成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 178686-24-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 178686-24-3
Chemical Structure| 178686-24-3
Structure of 178686-24-3 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 178686-24-3 ]

Related Doc. of [ 178686-24-3 ]

Alternatived Products of [ 178686-24-3 ]
Product Citations

Product Details of [ 178686-24-3 ]

CAS No. :178686-24-3 MDL No. :MFCD00058678
Formula : C9H9NO5 Boiling Point : -
Linear Structure Formula :- InChI Key :MDWLNBVKBMKTKN-UHFFFAOYSA-N
M.W : 211.17 Pubchem ID :584878
Synonyms :

Calculated chemistry of [ 178686-24-3 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 15
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.22
Num. rotatable bonds : 4
Num. H-bond acceptors : 5.0
Num. H-bond donors : 1.0
Molar Refractivity : 53.97
TPSA : 92.35 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -6.35 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.89
Log Po/w (XLOGP3) : 1.75
Log Po/w (WLOGP) : 1.51
Log Po/w (MLOGP) : -0.2
Log Po/w (SILICOS-IT) : -0.27
Consensus Log Po/w : 0.74

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -2.28
Solubility : 1.1 mg/ml ; 0.0052 mol/l
Class : Soluble
Log S (Ali) : -3.31
Solubility : 0.104 mg/ml ; 0.000494 mol/l
Class : Soluble
Log S (SILICOS-IT) : -1.69
Solubility : 4.3 mg/ml ; 0.0204 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 3.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 2.27

Safety of [ 178686-24-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P280-P305+P351+P338 UN#:N/A
Hazard Statements:H302 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 178686-24-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 178686-24-3 ]

[ 178686-24-3 ] Synthesis Path-Downstream   1~18

  • 1
  • [ 178686-24-3 ]
  • [ 26391-06-0 ]
  • (Z)-N,N-diethyl-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)acrylamide [ No CAS ]
  • [ 857629-79-9 ]
YieldReaction ConditionsOperation in experiment
With piperidine; acetic acid; In toluene; at 100 - 115℃; for 15.0h;Heating / reflux; Charge <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> 20g (0. 0947mole) of the formula 2 where R= ethyl and N, N-diethylamino cyanoacetamide of the formula (3) 14. 6g, (0.1042), acetic acid 3.13g and piperidine 4.45g along with toluene 200ml and heated to reflux temperature of about 100-115 C with continuous removal of water azeotrophically 15 hours. After the reaction is over the reaction mixture is concentrated to a volume of 20-30ml quenched in to dilute hydrochloric acid and chilled water 200ml and stirred for 60 minutes. The precipitated solid was filtered and dried to get 30g (95%), the HPLC purity is 94% (including isomer) of N, N-DIETHYL - 2-CYANO-3- (-3-ETHOXY-4-HYDROXY-5 NITROPHENYL) ACRYLAMIDE. The product is used as such directly to the. next stage. MR = 110.1- 117. 2 C.
  • 2
  • [ 121-32-4 ]
  • [ 178686-24-3 ]
YieldReaction ConditionsOperation in experiment
With nitric acid; In water; acetic acid; for 17.0h; a). 3-Ethoxy-4-hydroxy-5-nitro-benzaldehyde To a solution of 3-ethoxy-4-hydroxybenzaldehyde (5 g) in acetic acid (50 ml) was added nitric acid (1.4 ml) in 2 portions. The resulting suspension was stirred for 17 h. The solid was collected by filtration, washed with water and dried in vacuo.Yield: 5.07 g.
With nitric acid; acetic acid; for 17.0h; Example 14; Propane- 1 -sulfonic acid r5-(3-cvano-2-methyl-5-oxo-7-propyl-l,4,5,6,7,8-hexahvdro- quinolin-4- vD-3 -ethoxy-2-(3 -methoxy-benzyloxy) -phenyll -amide(a). 3-Ethoxy-4-hvdroxy-5-nitro-benzaldehvdeTo a solution of 3-ethoxy-4-hydroxybenzaldehyde (5 g) in acetic acid (50 ml) was added nitric acid (1.4 ml) in 2 portions. The resulting suspension was stirred for 17 h. The solid was collected by filtration, washed with water and dried in vacuo.Yield: 5.07 g.
  • 3
  • [ 178686-24-3 ]
  • [ 874-98-6 ]
  • 3-ethoxy-4-(3-methoxy-benzyloxy)-5-nitro-benzaldehyde [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetra-(n-butyl)ammonium iodide; potassium carbonate; In N,N-dimethyl-formamide; at 60℃; for 1.5h; Example 4; 4-r3-Ethoxy-4-(3-methoxy-benzyloxy)-5-nitro-phenyll-2-methyl-5-oxo-7-propyl- 1,4,5, 6,7,8-hexahvdro-quinoline-3-carbonitrile(a). 3-Ethoxy-4-(3-methoxy-benzyloxy)-5-nitro-benzaldehvdeA mixture of <strong>[178686-24-3]5-nitro-3-ethoxy-4-hydroxybenzaldehyde</strong> (100 mg), 3-methoxybenzyl bromide (73 mul), potassium carbonate (144 mg) and tetrabutylammonium iodide (10 mg) in DMF (5 ml) was stirred at 60 0C for 90 min. The mixture was poured into water and extracted with ethyl acetate. The organic layer was dried (MgSO4), filtered and concentrated in vacuo. The residue was purified by chromatography on silicagel in heptane/ethyl acetate 2/1 (v/v) as eluent.Yield: 43 mg.
  • 4
  • [ 178686-24-3 ]
  • [ 1118-61-2 ]
  • [ 57641-89-1 ]
  • 4-(3-ethoxy-4-hydroxy-5-nitro-phenyl)-2-methyl-5-oxo-7-propyl-1,4,5,6,7,8-hexahydro-quinoline-3-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
In ethanol; for 17.0h;Heating / reflux; (b). 4-(3-Ethoxy-4-hvdroxy-5-nitro-phenviy2-methyl-5-oxo-7-propyl-l,4,5, 6,7,8- hexahydro-quinoline-3 -carbonitrileA mixture of <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitro-benzaldehyde</strong> (1.5 g), 3-aminocrotonitrile (584 mg) and 5-propylcyclohexane-l,3-dione (1.09 g) in ethanol (60 ml) was heated at reflux for 17 h. The mixture was concentrated in vacuo. The residue was purified by chromatography on silicagel in heptane/ethyl acetate 1/0 - > 0/1 (v/v) as eluent. EPO <DP n="43"/>Yield: 1.3 g. MS-ESI: [M+H]+ = 412.3
  • 5
  • [ 178686-24-3 ]
  • [ 870-64-4 ]
  • [ 57641-89-1 ]
  • 4-(3-ethoxy-4-hydroxy-5-nitro-phenyl)-2-methyl-5-oxo-7-propyl-1,4,5,6,7,8-hexahydro-quinoline-3-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
In ethanol; for 17.0h;Heating / reflux; (b). 4-(3-Ethoxy-4-hydroxy-5-nitro-phenyl)-2-methyl-5-oxo-7-propyl-1,4,5,6,7,8-hexahydro-quinoline-3-carbonitrile A mixture of <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitro-benzaldehyde</strong> (1.5 g), 3-aminocrotonitrile (584 mg) and 5-propylcyclohexane-1,3-dione (1.09 g) in ethanol (60 ml) was heated at reflux for 17 h. The mixture was concentrated in vacuo. The residue was purified by chromatography on silicagel in heptane/ethyl acetate 1/0?0/1 (v/v) as eluent.Yield: 1.3 g. MS-ESI: [M+H]+=412.3
  • 6
  • [ 178686-24-3 ]
  • [ 1356060-06-4 ]
  • 7
  • [ 178686-24-3 ]
  • [ 1356060-13-3 ]
  • 8
  • [ 178686-24-3 ]
  • [ 1356060-14-4 ]
  • 9
  • [ 451-40-1 ]
  • [ 178686-24-3 ]
  • [ 631-61-8 ]
  • [ 1356059-92-1 ]
YieldReaction ConditionsOperation in experiment
13% With cycl-isopropylidene malonate; acetic acid;Reflux; [00159] A mixture of 1,2-diphenylethanone (150 mg, 0.76 mmol), 3-ethoxy-4- hydroxy- 5 -nitrobenzaldehyde (194 mg, 0.92 mmol), meldrum's acid (132 mg, 0.92 mmol) and ammonium acetate (71 mg, 0.92 mmol) in acetic acid (5 mL) was refluxed overnight. The solvent was removed under reduced pressure and the residue was purified by silica gel column chromatography (EtOAc : PE=2: 1) and prep-HPLC (0.1% TFA as additive) to afford Compound 1 as yellow solid (40 mg, yield: 13%). 1H NMR (DMSO- 6 300 MHz): delta 10.20 (s, 1H), 9.60 (s, 1H), 7.47 (d, J = 3.0 Hz, 1H), 7.24-7.18 (m, 6H), 7.01-6.96 (m, 3H), 6.79 (d, J = 8.1 Hz, 2H), 4.06 (q, J = 6.0 Hz, 2H), 3.96 (d, J = 5.1 Hz, 1H), 3.14-3.07 (m, 2H),1.31 (t, J = 1.2 Hz, 3H); MS (ESI): m/z 430.9 [M+H+].
  • 10
  • [ 178686-24-3 ]
  • [ 1179511-06-8 ]
  • [ 631-61-8 ]
  • [ 1356059-93-2 ]
YieldReaction ConditionsOperation in experiment
12% With cycl-isopropylidene malonate; acetic acid;Reflux; Inert atmosphere; [00160] A mixture of l-(pyridin-3-yl)-2-(thiophen-3-yl)ethanone (Intermediate 1, seeExample 18 for synthesic description of all intermediates) (230 mg, 1.1 mmol), 3-ethoxy-4- hydroxy- 5 -nitrobenzaldehyde (296 mg, 1.4 mmol), meldrum's acid (202 mg, 1.4 mmol) and AcONH4 (108 mg, 1.4 mmol) in AcOH (3 mL) was refluxed under N2 overnight. The mixture was concentrated under reduced pressure and the residue was purified by prep-HPLC (0.1% TFA as additive) to give Compound 2 (60 mg, 12%). 1H NMR (MeOD 400 MHz): delta 8.70 (d, J = 5.2 Hz, 1H), 8.67 (s, 1H), 8.30 (d, J = 8.0 Hz, 1H), 7.90-7.62 (m, 1H), 7.72-7.60 (m, 1H), 7.27-7.24 (m, 2H), 6.94-6.92 (m, 1H), 6.58 (d, J = 4.8 Hz, 1H), 4.20-4.11 (m, 3H), 3.30-3.25 (m, 1H), 2.79-2.74 (dd, J = 16.2, 3.2 Hz, 1H), 1.45 (t, J = 6.8 Hz, 3H). MS (ESI): m/z 438.3 [M+l]+
  • 11
  • [ 178686-24-3 ]
  • [ 1283118-47-7 ]
  • [ 631-61-8 ]
  • [ 1356059-95-4 ]
YieldReaction ConditionsOperation in experiment
6% With cycl-isopropylidene malonate; acetic acid;Reflux; Inert atmosphere; [00162] A mixture of l-(l-methyl-lH-pyrazol-4-yl)-2-(thiophen-3-yl)ethanone(Intermediate 3) (150 mg, 0.73 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (185 mg, 0.87 mmol), meldrum's acid (125 mg, 0.87 mmol) and AcONH4 (84 mg, 1.1 mmol) in AcOH (3 mL) was refluxed under N2 overnight. The mixture was concentrated under reduced pressure and the residue was purified by prep-HPLC (0.1% TFA as additive) to giveCompound 4 as yellow solid (20 mg, 6%). 1H NMR (DMSO- 6, 400 MHz): delta 10.20 (s, 1H), 9.43 (s, 1H), 7.62 (s, 1H), 7.42-7.36 (m, 2H), 7.19-7.11 (m, 1H), 7.06 (s, 2H), 6.70-6.68 (m, 1H), 4.11-4.03 (m, 2H), 3.95-3.92 (m, 1H), 3.77 (s, 3H), 3.08 (dd, J = 16.4, 7.6 Hz, 1H), 2.60-2.52 (m, 1H), 1.34 (t, J = 6.8 Hz, 3H). MS (ESI): m/z 440.9 [M+l]+.
  • 12
  • [ 178686-24-3 ]
  • [ 57-13-6 ]
  • [ 2001-28-7 ]
  • [ 1283117-17-8 ]
YieldReaction ConditionsOperation in experiment
40% With hydrogenchloride; In ethanol; water;Reflux; 00161] A mixture of 2-phenyl-l-p-tolylethanone (65 mg, 0.31 mmol), 3-ethoxy-4- hydroxy-5-nitrobenzaldehyde (54 mg, 0.26 mmol), urea (56 mg, 0.93 mmol), andconcentrated HC1 solution (0.03 mL, 0.31 mmol) in EtOH (5 mL) was refluxed overnight. The mixture was evaporated in vacuo and the residue was purified by preparative HPLC to give compound 16 (455.19 mg, yield 40%). 1H NMR (DMSO- d6 400 MHz): delta 10.28 (s, 1H), 8.64 (s, 1H), 7.51 (s, 1H), 7.42 (s, 1H), 7.17 (s, 1H), 7.08-6.96 (m, 7H), 6.80 (d, J = 6.8 Hz, 2H), 5.14 (d, J = 2.4 Hz, 1H), 4.05-3.98 (m, 2H), 2.23 (s, 3H), 1.31 (t, J = 6.8 Hz, 3H); MS (ESI): m/z 446.2 [M+l]+.
  • 13
  • [ 178686-24-3 ]
  • [ 40281-50-3 ]
  • [ 57-13-6 ]
  • [ 1283117-41-8 ]
YieldReaction ConditionsOperation in experiment
13% With hydrogenchloride; In ethanol; water;Reflux; 00177] A mixture of l-(3-fluorophenyl)-2-phenylethanone (100 mg, 0.47 mmol), 3- ethoxy-4-hydroxy-5-nitrobenzaldehyde (82 mg, 0.39 mmol), urea (70 mg, 1.17 mmol), and concentrated HC1 solution (0.03 mL, 0.39 mmol) in EtOH (5 mL) was refluxed overnight. The mixture was evaporated in vacuo and purified by preparative HPLC to give Compound 32 (22.35 mg, yield 13%) as a yellow solid. 1H NMR (DMSO-d6 400 MHz): delta 10.28 (s, IH), 8.79 (s, IH), 7.56 (s, IH), 7.42 (s, IH), 7.30-7.25 (m, IH), 7.16 (s, IH), 7.12-6.99 (m, 6H), 6.86 (d, J = 1.6 Hz, 2H), 5.23 (d, J = 2.4 Hz, IH), 4.04 (q, J = 7.2 Hz, 2H), 1.33 (t, J = 1.2 Hz, 3H); MS (ESI): m/z 450.0 [M+l]+.
  • 14
  • [ 178686-24-3 ]
  • [ 325-62-2 ]
  • [ 57-13-6 ]
  • [ 1283117-48-5 ]
YieldReaction ConditionsOperation in experiment
48% With hydrogenchloride; In ethanol; water;Reflux; [00184] A mixture of l-(3-fluoro-4-methoxyphenyl)-2-phenylethanone (100 mg, 0.41 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (72 mg, 0.34 mmol), urea (61 mg, 1.02 mmol), and concentrated HCl solution (0.03 mL, 0.34 mmol) in EtOH (5 mL) was refluxed overnight. The mixture was evaporated in vacuo, and the residue was purified by preparative HPLC to give Compound 39 (78 mg, yield 48%). 1H NMR (DMSO- 6 400 MHz): delta 10.28 (s, 1H), 8.71 (s, 1H), 7.53 (s, 1H), 7.42 (s, 1H), 7.17 (s, 1H), 7.10-7.01 (m, 5H), 6.95 (d, J = 92 Hz, 1H), 6.85 (d, J = 6.8 Hz, 2H), 5.18 (s, 1H), 4.08-4.01 (m, 2H), 3.79 (s, 3H), 1.33 (t, J = 7.2 Hz, 3H); MS (ESI): m/z 480.0 [M+l]+.
  • 15
  • [ 178686-24-3 ]
  • [ 57-13-6 ]
  • [ 93534-22-6 ]
  • [ 1283117-56-5 ]
YieldReaction ConditionsOperation in experiment
17% With hydrogenchloride; In ethanol; water; for 48.0h;Reflux; 00192] To a solution of l-(3,4-dichlorophenyl)-2-phenylethanone (Intermediate 19)(100 mg, 0.38 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (74.4 mg, 0.38 mmol), and urea (68.5 mg, 1.14 mmol) in 5 mL of ethanol was added 0.2 mL of concentrated HC1 solution, and the mixture was refluxed for 2 days. After the solvent was removed under reduced pressure, the residue was purified by reverse-phase preparatory HPLC (26-53% acetonitrile + 0.1% trifluoroacetic acid in water + 0.1% trifluoroacetic acid, over 15 min.) to give Compound 47 (32 mg, yield 17.0%). 1H NMR (DMSO- 6 300 MHz) delta 10.28 (s, 1H), 8.85 (s, 1H), 7.58 (s, 1H), 7.48 (t, J = 1.5 Hz, 2H), 7.41 (d, J = 1.8 Hz, 1H), 7.13-7.05 (m, 5H), 6.88 (t, J = 1.8 Hz, 2H), 5.25 (d, J = 2.1 Hz, 1H), 4.02 (m, 2H), 1.32 (t, J = 6.9 Hz, 3H); MS(ESI): m/z 499.9 [M+l]+.
  • 16
  • [ 1620-55-9 ]
  • [ 178686-24-3 ]
  • [ 57-13-6 ]
  • [ 1283117-89-4 ]
YieldReaction ConditionsOperation in experiment
38.3% With hydrogenchloride; In ethanol; water; at 79℃; for 80h; 00222] A mixture of l-phenyl-2-(pyridin-4-yl)ethanone (Intermediate 36) (100 mg,0.507 mmol), 3-ethoxy-4-hydroxy-5-nitrobenzaldehyde (107 mg, 0.507 mmol), urea (91.3 mg, 4.587 mmol), and concentrated hydrochloric acid (0.3 mL) in ethanol (1 mL) was refluxed at 79C for 80 h. After being cooled down to room temperature, the mixture was evaporated, and purified by preparative HPLC to give Compound 74 (80.1 mg, yield 38.3%). 1H NMR (DMSO- 6 400MHz): delta 10.41 (s, IH), 9.57 (s, IH), 8.34 (d, J = 6.4 Hz, 2H), 8.02 (s, IH), 7.50-7.42 (m, 4H), 7.39 (d, J = 1.2 Hz, 2H), 7.34 (d, J = 1.6 Hz, IH), 7.06 (d, J = 6.4 Hz, 2H), 5.39 (d, J = 3.2 Hz, IH), 4.15-4.10 (m, 2H), 1.38-1.35 (m, 3H); MS (ESI): m/z 433.0 [M+H]+.
  • 17
  • [ 1081-48-7 ]
  • [ 178686-24-3 ]
  • [ 57-13-6 ]
  • [ 1283118-01-3 ]
YieldReaction ConditionsOperation in experiment
43.7% With hydrogenchloride; In ethanol; water; at 78℃; for 70.0h; [00233] A mixture of l-phenyl-2-(pyridin-3-yl)ethanone (Intermediate 42) (200 mg,1.01 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (213.3 mg, 1.01 mmol), urea (181.8 mg, 3.03 mmol), and concentrated hydrochloric acid solution (0.5 mL) in ethanol (2 mL) was refluxed at 78C for 70 h. After being cooled down to room temperature, the reaction mixture was evaporated, and the residue was purified by preparative HPLC to giveCompound 84 (191.1 mg, yield 43.7%). 1H NMR (DMSO- 6 400MHz): delta 10.34 (s, 1H), 9.06 (s, 1H), 8.35-8.33 (m, 1H), 8.10 (d, J = 2.0 Hz, 1H), 7.72 (s, 1H), 7.59 (d, J = 8.0 Hz, 1H), 7.45-7.39 (m, 2H), 7.33-7.23 (m, 6H), 5.39 (d, J = 2.8 Hz, 1H), 4.11-4.06 (m, 2H), 1.36-1.33 (m, 3H); MS (ESI): m/z 433.0 [M+H]+.
  • 18
  • [ 178686-24-3 ]
  • [ 29955-26-8 ]
  • [ 57-13-6 ]
  • [ 1283117-29-2 ]
YieldReaction ConditionsOperation in experiment
2.5% With hydrogenchloride; In ethanol; water; for 96.0h;Reflux; 00168] To a solution of 2-(3-methoxyphenyl)-l-phenylethanone (400 mg, 1.77 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (374 mg, 1.77 mmol) and urea (244 mg, 5.31 mmol) in 20 mL of ethanol was added 0.2 mL of concentrated HCl, then the mixture was stirred at reflux for 4 days. After the solvent was removed under reduced pressure, the residue was purified by HPLC (35-65% acetonitrile + 0.1% trifluoroacetic acid in water, over 15 min.) and then purified by thin layer chromatography (PE:EtOAc=l :2) further to give Compound 23 (20 mg, yield 2.5%). 1H NMR (CD3OD 400 MHz): delta 7.43 (s, IH), 7.17 (s, 5H), 6.86-6.82 (m, 2H), 6.48 (d, J=6.4 Hz, IH), 6.40 (d, J=8.0 Hz, IH), 6.30 (s, IH), 5.03 (s, IH), 3.91-3.89 (m, 2H), 3.37 (s, 3H), 1.30 (t, J=7.2 Hz, 3H); MS (ESI): mJz 462.3 [M+l]+.
Recommend Products
Same Skeleton Products

Technical Information

? Acidity of Phenols ? Barbier Coupling Reaction ? Baylis-Hillman Reaction ? Benzylic Oxidation ? Birch Reduction ? Blanc Chloromethylation ? Bucherer-Bergs Reaction ? Chan-Lam Coupling Reaction ? Clemmensen Reduction ? Complex Metal Hydride Reductions ? Corey-Chaykovsky Reaction ? Corey-Fuchs Reaction ? Electrophilic Substitution of the Phenol Aromatic Ring ? Etherification Reaction of Phenolic Hydroxyl Group ? Fischer Indole Synthesis ? Friedel-Crafts Reaction ? Grignard Reaction ? Halogenation of Phenols ? Hantzsch Dihydropyridine Synthesis ? Heat of Combustion ? Henry Nitroaldol Reaction ? Horner-Wadsworth-Emmons Reaction ? Hydride Reductions ? Hydrogenolysis of Benzyl Ether ? Julia-Kocienski Olefination ? Knoevenagel Condensation ? Leuckart-Wallach Reaction ? McMurry Coupling ? Meerwein-Ponndorf-Verley Reduction ? Mukaiyama Aldol Reaction ? Nomenclature of Ethers ? Nozaki-Hiyama-Kishi Reaction ? Oxidation of Phenols ? Passerini Reaction ? Paternò-Büchi Reaction ? Pechmann Coumarin Synthesis ? Petasis Reaction ? Pictet-Spengler Tetrahydroisoquinoline Synthesis ? Preparation of Aldehydes and Ketones ? Preparation of Alkylbenzene ? Preparation of Amines ? Preparation of Ethers ? Prins Reaction ? Reactions of Aldehydes and Ketones ? Reactions of Amines ? Reactions of Benzene and Substituted Benzenes ? Reactions of Ethers ? Reformatsky Reaction ? Reimer-Tiemann Reaction ? Schlosser Modification of the Wittig Reaction ? Schmidt Reaction ? Stetter Reaction ? Stobbe Condensation ? Tebbe Olefination ? Ugi Reaction ? Vilsmeier-Haack Reaction ? Wittig Reaction ? Wolff-Kishner Reduction
Historical Records

Related Functional Groups of
[ 178686-24-3 ]

Aryls

Chemical Structure| 6635-20-7

[ 6635-20-7 ]

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde

Similarity: 0.97

Chemical Structure| 15785-54-3

[ 15785-54-3 ]

4-Hydroxy-3-methoxy-5-nitrobenzoic acid

Similarity: 0.92

Chemical Structure| 31680-08-7

[ 31680-08-7 ]

4-Methoxy-3-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 80410-57-7

[ 80410-57-7 ]

3-Methoxy-4-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 2450-27-3

[ 2450-27-3 ]

4-(Benzyloxy)-3-methoxy-2-nitrobenzaldehyde

Similarity: 0.89

Aldehydes

Chemical Structure| 6635-20-7

[ 6635-20-7 ]

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde

Similarity: 0.97

Chemical Structure| 31680-08-7

[ 31680-08-7 ]

4-Methoxy-3-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 80410-57-7

[ 80410-57-7 ]

3-Methoxy-4-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 2450-27-3

[ 2450-27-3 ]

4-(Benzyloxy)-3-methoxy-2-nitrobenzaldehyde

Similarity: 0.89

Chemical Structure| 2450-26-2

[ 2450-26-2 ]

4-Hydroxy-3-methoxy-2-nitrobenzaldehyde

Similarity: 0.89

Ethers

Chemical Structure| 6635-20-7

[ 6635-20-7 ]

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde

Similarity: 0.97

Chemical Structure| 15785-54-3

[ 15785-54-3 ]

4-Hydroxy-3-methoxy-5-nitrobenzoic acid

Similarity: 0.92

Chemical Structure| 31680-08-7

[ 31680-08-7 ]

4-Methoxy-3-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 80410-57-7

[ 80410-57-7 ]

3-Methoxy-4-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 2450-27-3

[ 2450-27-3 ]

4-(Benzyloxy)-3-methoxy-2-nitrobenzaldehyde

Similarity: 0.89

Nitroes

Chemical Structure| 6635-20-7

[ 6635-20-7 ]

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde

Similarity: 0.97

Chemical Structure| 15785-54-3

[ 15785-54-3 ]

4-Hydroxy-3-methoxy-5-nitrobenzoic acid

Similarity: 0.92

Chemical Structure| 31680-08-7

[ 31680-08-7 ]

4-Methoxy-3-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 80410-57-7

[ 80410-57-7 ]

3-Methoxy-4-nitrobenzaldehyde

Similarity: 0.91

Chemical Structure| 2450-27-3

[ 2450-27-3 ]

4-(Benzyloxy)-3-methoxy-2-nitrobenzaldehyde

Similarity: 0.89

; ;