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Ezetimibe is a cholesterol-absorption inhibitor, reduces levels of low-density lipoprotein (LDL) cholesterol when added to statin treatment. It's also a Niemann-Pick C1-like1 (NPC1L1) inhibitor and Nrf2 activator.
Synonyms: SCH 58235; Ezetrol; Ezetimibe, Zetia, Ezetrol,
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 163222-33-1 |
Formula : | C24H21F2NO3 |
M.W : | 409.43 |
SMILES Code : | O=C1N(C2=CC=C(F)C=C2)[C@H](C3=CC=C(O)C=C3)[C@H]1CC[C@@H](C4=CC=C(F)C=C4)O |
Synonyms : |
SCH 58235; Ezetrol; Ezetimibe, Zetia, Ezetrol,
|
MDL No. : | MFCD00937872 |
InChI Key : | OLNTVTPDXPETLC-XPWALMASSA-N |
Pubchem ID : | 150311 |
GHS Pictogram: |
![]() ![]() ![]() |
Signal Word: | Danger |
Hazard Statements: | H302-H319-H372-H410 |
Precautionary Statements: | P273-P301+P312+P330-P305+P351+P338-P314 |
Class: | 9 |
UN#: | 3077 |
Packing Group: | Ⅲ |
In Vitro:
Concentration | Treated Time | Description | Reference |
AS patient PBMCs | 20 μM | 1 day | To investigate the effect of Ezetimibe on Th17 cell differentiation in AS patient PBMCs, results showed that Ezetimibe significantly reduced the number of Th17 cells. | PMC9428320 |
Human primary lung fibroblasts (hLFs) | 20 μM | 24 hours | Ezetimibe inhibited TGFβ1-induced myofibroblast differentiation, restored intracellular cholesterol distribution, and suppressed fibrotic gene expression through the mTORC1-autophagy axis. | PMC11096666 |
Mouse primary lung fibroblasts (mLFs) | 20 μM | 24 hours | Ezetimibe inhibited TGFβ1-induced myofibroblast differentiation, restored intracellular cholesterol distribution, and suppressed fibrotic gene expression through the mTORC1-autophagy axis. | PMC11096666 |
Mouse spleen cells | 10 and 20 μM | 3 days | To investigate the effect of Ezetimibe on immune cell differentiation, results showed that Ezetimibe increased the number of Treg cells and reduced the number of Th17 and Th1 cells. | PMC9428320 |
Rat mesenteric artery smooth muscle cells | 5–50 μM | To explore the direct vascular effect of Ezetimibe on rat mesenteric arteries, it was found that Ezetimibe induced concentration-dependent vasodilation. | PMC10531054 |
In Vivo:
Administration | Dosage | Frequency | Description | Reference |
C57BL/6J mice | Bleomycin-induced pulmonary fibrosis model | Oral gavage | 2 mg/kg | Three times a week for 21 days | Ezetimibe ameliorated bleomycin-induced pulmonary fibrosis by inhibiting mTORC1 activity and increasing autophagic flux, reducing collagen accumulation and improving respiratory function. | PMC11096666 |
BALB/c background SKG mice | Ankylosing spondylitis model mice | Oral | 10 mg/kg | Once daily for 6 weeks | To investigate the efficacy of Ezetimibe in ankylosing spondylitis model mice, results showed that Ezetimibe significantly inhibited joint inflammation and spinal bending, and reduced the expression of proinflammatory cytokines. | PMC9428320 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00101439 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00101439 | - | Completed | - | - | |
NCT00863265 | - | Completed | - | - | |
NCT00863265 | Hypercholesterolemia ... More >> Coronary Heart Disease Less << | Early Phase 1 | Completed | - | United States, Utah ... More >> Center for Advance Nutrition at Utah State University Logan, Utah, United States, 84322-4715 Less << |
NCT00677248 | Hypercholesterolemia | Phase 2 | Completed | - | Sweden ... More >> Karo Bio AB HUddinge, Sweden Less << |
NCT00651391 | Hypercholesterolemia ... More >> Atherosclerosis Less << | Phase 3 | Terminated(Slow enrollment) | - | - |
NCT00905905 | Myocardial Infarction | Phase 4 | Completed | - | Brazil ... More >> Hospital de Base do Distrito Federal Brasilia, DF, Brazil, 70673103 Less << |
NCT00699023 | Postprandial Lipemia ... More >> Type 2 Diabetes Less << | Phase 4 | Completed | - | Italy ... More >> Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy, 80131 Less << |
NCT00299884 | - | Completed | - | Canada, Ontario ... More >> Vascular Disease Prevention and Research Centre, Hotel Dieu Hospital Kingston, Ontario, Canada, K7L 5G2 Less << | |
NCT00753883 | Hyperlipidemia | Phase 4 | Completed | - | - |
NCT00423579 | Hypercholesterolemia ... More >> Coronary Disease Less << | Phase 4 | Completed | - | - |
NCT00423579 | - | Completed | - | - | |
NCT03051100 | Hypercholesterolemia | Phase 2 | Completed | - | United States, Illinois ... More >> PMG Research of Christie Clinic Champaign, Illinois, United States, 61820 United States, North Carolina PMG Research of Cary Cary, North Carolina, United States, 27518 PMG Research of Charlotte Charlotte, North Carolina, United States, 28209 Sensenbrenner Primary Care Charlotte, North Carolina, United States, 28277 PMG Research of Hickory Hickory, North Carolina, United States, 28601 PMG Research of Raleigh Raleigh, North Carolina, United States, 27609 PMG Research of Rocky Mount Rocky Mount, North Carolina, United States, 27804 PMG Research Salisbury Salisbury, North Carolina, United States, 28144 PMG Research of Wilmington Wilmington, North Carolina, United States, 28401 United States, South Carolina PMG Research of Charleston Mount Pleasant, South Carolina, United States, 29464 United States, Virginia Hampton Roads Center for Clinical Research Virginia Beach, Virginia, United States, 23451 Less << |
NCT00909389 | - | Completed | - | - | |
NCT00909389 | - | Completed | - | - | |
NCT00481351 | Coronary Heart Disease | Phase 4 | Completed | - | - |
NCT01603758 | Coronary Heart Disease|Cardiov... More >>ascular Disease|Dyslipidemia|Disorder of Cholesterol Metabolism Less << | PHASE1 | COMPLETED | 2025-06-15 | Washington University School o... More >>f Medicine, St. Louis, Missouri, 63110, United States Less << |
NCT00481351 | - | Completed | - | - | |
NCT00268697 | Hypercholesterolemia | Phase 3 | Completed | - | Estonia ... More >> Tallinn, Estonia Tartu, Estonia Latvia Riga, Latvia Russian Federation Moscow, Russian Federation Saratov, Russian Federation Smolensk, Russian Federation St. Petersburg, Russian Federation Tyumen, Russian Federation Serbia Kragujevac, Serbia Less << |
NCT01370590 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT01370590 | - | Completed | - | - | |
NCT01370603 | - | Completed | - | - | |
NCT00705081 | - | Completed | - | - | |
NCT00705081 | - | Completed | - | - | |
NCT00819403 | Metabolic Syndrome | Phase 4 | Completed | - | United States, Maryland ... More >> VA Maryland Health Care System Baltimore, Maryland, United States, 21201 University of Maryland Medical Center Baltimore, Maryland, United States, 21202 Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 Less << |
NCT01375764 | - | Completed | - | - | |
NCT00819403 | - | Completed | - | - | |
NCT01035320 | Diabetes Mellitus|Impaired Ren... More >>al Function Less << | PHASE4 | COMPLETED | 2025-06-12 | Department of Medicine, Clinic... More >>al Pharmacology Unit, Karolinska University Hospital (Solna), Stockholm, 171 76, Sweden Less << |
NCT02127320 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of, Korea, Republic of Less << |
NCT00650689 | Hypercholesterolemia ... More >> Atherosclerosis Coronary Artery Disease Less << | Phase 3 | Completed | - | - |
NCT01375764 | Hyperlipidemia | Phase 2 | Completed | - | - |
NCT00701727 | Hypercholesterolemia | Phase 4 | Completed | - | United States, Illinois ... More >> Radiant Research Chicago, Illinois, United States, 60610 Less << |
NCT00701727 | - | Completed | - | - | |
NCT03771053 | Coronary Heart Disease | Not Applicable | Recruiting | December 31, 2019 | China, Beijing ... More >> Chinese People's Liberation Army General Hospital Recruiting Peking, Beijing, China, 100853 Contact: Geng Qian, MD ?? 086-01055499312 ?? qiangeng9396@263.net ?? Contact: Yun-dai Chen, MD ?? 086-01055499309 ?? cyundai@126.com Less << |
NCT00474123 | Stable Angina | Not Applicable | Completed | - | Brazil ... More >> Heart Institute (InCor) HOSPITAL DAS CLINICAS DA FACULDADE DE MEDICINA DA UNIVERSIDADE DE SAO PAULO (HCFMUSP) Sao Paulo, Brazil, 05403-000 Less << |
NCT00474123 | - | Completed | - | - | |
NCT03337308 | Hyperlipidemias | Phase 3 | Completed | - | United States, Iowa ... More >> PMG Research of McFarland Ames, Iowa, United States, 50010 United States, New Hampshire Foundation Cardiology Nashua, New Hampshire, United States, 03060 United States, North Carolina PMG Research of Piedmont Healthcare Statesville, North Carolina, United States, 28625 PMG Research of Wilmington Wilmington, North Carolina, United States, 28401 United States, Tennessee PMG Research of Knoxville Knoxville, Tennessee, United States, 37912 Less << |
NCT00652847 | Hypercholesterolemia | Phase 4 | Completed | - | - |
NCT01941836 | Hypercholesterolemia | Phase 2 | Completed | - | - |
NCT00651144 | Hypercholesterolemia ... More >> Atherosclerosis Less << | Phase 1 | Completed | - | - |
NCT00705211 | - | Completed | - | - | |
NCT00783263 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00783263 | - | Completed | - | - | |
NCT00932620 | - | Completed | - | - | |
NCT00932620 | Hypercholesterolemia | Phase 4 | Completed | - | Greece ... More >> University Hospital of Ioannina Ioannina, Greece, 45 110 Less << |
NCT00653835 | Hypercholesterolaemia ... More >> Atherosclerosis Less << | Phase 4 | Completed | - | - |
NCT01370603 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00651963 | Lipid Metabolism Disorder | Phase 4 | Completed | - | - |
NCT00650819 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT01597700 | Hypercholesterolaemia | Phase 1 | Completed | - | India ... More >> GSK Investigational Site Electronics City, Bengalore, India, 560100 Less << |
NCT00704444 | - | Completed | - | - | |
NCT00653796 | Hypercholesterolemia ... More >> Atherosclerosis Less << | Phase 4 | Completed | - | - |
NCT00965055 | High Cholesterol ... More >> Coronary Artery Disease Less << | Phase 3 | Terminated(The study was termi... More >>nated due to inability to recruit subjects. A total of 2/100 anticipated were radomized.) Less << | - | United States, California ... More >> UCSD Medical Center in Hillcrest Clinical Trials Facility San Diego, California, United States, 92103 Less << |
NCT01241097 | Endothelial Function | Not Applicable | Unknown | December 2011 | Brazil ... More >> Escola Bahiana de Medicina e Saúde Púiblica Recruiting Salvador, Bahia, Brazil, 40000 Contact: Marilia G Rodrigues, MD ?? 55-71-3359485 ?? mgaleffi@cardiol.br ?? Contact: Paulo Roberto P Lima, student ?? 55-71-99184765 ?? prpassoslima@hotmail.com ?? Sub-Investigator: Carolina Garcez, student Less << |
NCT00817843 | Metabolic Syndrome | Phase 4 | Completed | - | Netherlands ... More >> Academic Medical Center Amsterdam, Netherlands, 1005 AZ Vascular Research Center Hoorn Hoorn, Netherlands, 1624 NP Department of Vascular Medicine UMC Utrecht Utrecht, Netherlands, 3584 CX Tweesteden Ziekenhuis Waalwijk, Netherlands, 5141 BM Spain Hospital Arnau de Vilanova Lleida, Spain, E-25198 Less << |
NCT00814723 | Hypercholesterolemia | Phase 4 | Completed | - | Austria ... More >> Depart. of Internal Medicine, Medical University of Graz Graz, Austria, 8036 Less << |
NCT00651404 | Hypercholesterolemia ... More >> Atherosclerosis Less << | Phase 3 | Completed | - | - |
NCT00650663 | Hypercholesterolemia ... More >> Atherosclerosis Less << | Phase 4 | Completed | - | - |
NCT00129402 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00129402 | - | Completed | - | - | |
NCT00652301 | Cholesterol | Phase 3 | Completed | - | - |
NCT03044665 | Cardiovascular Diseases ... More >> Cerebrovascular Disease Peripheral Atherosclerotic Disease Less << | Not Applicable | Recruiting | February 15, 2022 | Korea, Republic of ... More >> Division of Cardiology, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 03722 Contact: Yang-Soo Jang, MD, PhD Less << |
NCT03434613 | Nonalcoholic Fatty Liver Disea... More >>se Dyslipidemias Less << | Phase 4 | Not yet recruiting | September 1, 2019 | Korea, Republic of ... More >> Yonsei University College of Medicine, Department of Internal Medicine, Division of Endocrinology, Severance Hospital, Diabetes center Not yet recruiting Seoul, Korea, Republic of, 03722 Contact: Yong-ho Lee, M.D., Ph.D. ?? 82-2-2228-1943 ?? yholee@yuhs.ac Less << |
NCT02089867 | Coronary Artery Disease | Phase 2 Phase 3 | Completed | - | Brazil ... More >> Jose Rocha Faria Neto Curitiba, Paraná, Brazil, 80215-901 Less << |
NCT01611883 | Hypercholesterolemia | Phase 4 | Completed | - | - |
NCT01611883 | - | Completed | - | - | |
NCT00651014 | Hypercholesterolemia ... More >> Atherosclerosis Less << | Phase 4 | Terminated(slow subject recrui... More >>tment and lack of medical and scientific merit due to change in new standard of therapy during that same period.) Less << | - | - |
NCT03001076 | Hypercholesterolemia ... More >> Atherosclerosis Statin Adverse Reaction Less << | Phase 3 | Completed | - | United States, Texas ... More >> Georgetown, Texas, United States, 78626 Less << |
NCT02288338 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... More >> ChongKunDang Seoul, Korea, Republic of Less << |
NCT01103648 | Prediabetes H... More >>ypercholesterolemia Inflammation Cardiovascular Risk Less << | Not Applicable | Completed | - | Brazil ... More >> Hospital do Rim e Hipertensao da UNIFESP Sao Paulo, Brazil, 04038-002 Less << |
NCT01086020 | Coronary Artery Disease | Phase 4 | Unknown | December 2012 | China, Shanghai ... More >> Ruijin Hospital, Recruiting Shanghai, Shanghai, China, 200025 Contact: Ruiyan Zhang, MD ?? 862164370045 ext 665215 ?? zhangruiyan@263.net ?? Contact: Xin Chen, MD ?? 862164370045 ext 665380 ?? rjchenxin@yahoo.com.cn ?? Principal Investigator: Ruiyan Zhang, MD Less << |
NCT00319449 | Hypercholesterolemia ... More >> Coronary Arteriosclerosis Less << | Phase 4 | Completed | - | - |
NCT00817843 | - | Completed | - | - | |
NCT01584206 | Sitosterolemia | COMPLETED | 2025-12-16 | Richardson Centre for Function... More >>al Foods and Nutraceuticals, Winnipeg, Manitoba, R3T 2N2, Canada Less << | |
NCT01490229 | Coronary Artery Disease | Phase 4 | Unknown | December 2016 | Italy ... More >> San Raffaele Pisana Recruiting Rome, Italy, 00100 Contact: Giuseppe Marazzi, MD ?? +39 335 8381320 ?? giuseppe.marazzi@yahoo.com Less << |
NCT00319449 | - | Completed | - | - | |
NCT00653913 | Hypercholesterolemia | Phase 1 | Completed | - | - |
NCT00772551 | HIV | Phase 1 | Completed | - | United Kingdom ... More >> Chelsea and Westminster Hospital NHS Foundation Trust London, United Kingdom, SW10 9NH Less << |
NCT00653276 | Cholesterol | Phase 1 | Completed | - | - |
NCT01950884 | ?Non-alcoholic Steatohepatitis... More >> (NASH) Less << | Phase 4 | Unknown | December 2014 | Italy ... More >> Dipartimento Biomedico di Medicina Interna e Specialistica Di.Bi.M.I.S. Palermo, Italy, 90127 Less << |
NCT00202904 | Hypercholesterolemia ... More >> Coronary Heart Disease Less << | Phase 4 | Completed | - | - |
NCT00738985 | Cardiovascular Diseases ... More >> Hyperlipidemia Less << | Phase 4 | Withdrawn(The study was cancel... More >>led due to budget limitations) Less << | - | - |
NCT01766713 | Non Alcoholic Steatohepatitis | PHASE2 | COMPLETED | 2025-09-14 | University of California, San ... More >>Diego, San Diego, California, 92103, United States Less << |
NCT03217409 | Diabetes Mellitus and Hypercho... More >>lesterolemia Less << | Phase 4 | Recruiting | July 2018 | Korea, Republic of ... More >> Soon Chun Hyang University Hospital Cheonan Recruiting Cheonan, Korea, Republic of Soon Chun Hyang University Hospital Gumi Recruiting Gumi, Korea, Republic of Soon Chun Hyang University Hospital Bucheon Recruiting Gyeonggi-do, Korea, Republic of Soon Chun Hyang University Hospital Seoul Recruiting Seoul, Korea, Republic of Less << |
NCT01766713 | Non Alcoholic Steatohepatitis | PHASE2 | COMPLETED | 2025-09-14 | University of California, San ... More >>Diego, San Diego, California, 92103, United States Less << |
NCT01008345 | Coronary Artery Disease ... More >> Diabetes Less << | Phase 4 | Completed | - | Lebanon ... More >> Hotel Dieu de France Hospital Achrafieh, Beirut, Lebanon, 0000 Less << |
NCT00653445 | Hypercholesterolemia ... More >> Coronary Heart Disease Atherosclerosis Less << | Phase 3 | Completed | - | - |
NCT00867165 | Primary Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT02103049 | Dyslipidemia|Transplants | PHASE4 | COMPLETED | 2025-12-15 | University Medical Center Ljub... More >>ljana, Ljubljana, 1000, Slovenia Less << |
NCT00621101 | Pharmacokinetics ... More >> Drug Interactions Hypercholesterolemia Immunosuppression Less << | Phase 1 | Completed | - | Germany ... More >> Department of Clinical Pharmacology Greifswald, Germany, 17487 Less << |
NCT00654095 | - | Completed | - | - | |
NCT03277079 | Coronary Artery Disease | Phase 4 | Not yet recruiting | March 31, 2018 | Italy ... More >> Sapienza University Rome, Italy, 00161 Less << |
NCT00653523 | - | Completed | - | - | |
NCT01385631 | ST-Segment Elevation Myocardia... More >>l Infarction Less << | Phase 4 | Completed | - | Denmark ... More >> Department of Cardiology, Odense University Hospital Odense C, Denmark, 5000 Less << |
NCT00908011 | Hypercholesterolemia ... More >> HIV Infections Less << | Not Applicable | Completed | - | Canada, British Columbia ... More >> St. Paul's Hospital HIV Immunodeficiency/Metabolic Clinic Vancouver, British Columbia, Canada, V6Z 1Y6 Less << |
NCT00867165 | - | Completed | - | - | |
NCT00654095 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00908011 | - | Completed | - | - | |
NCT00704535 | Primary Hypercholesterolemia|H... More >>omozygous Familial Hypercholesterolemia Less << | COMPLETED | 2025-04-08 | - | |
NCT00653523 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00621699 | Pharmacokinetics ... More >> Drug Interactions Hypercholesterolemia Immunosuppression Less << | Phase 1 | Completed | - | Germany ... More >> Department of Clinical Pharmacology Greifswald, Germany, 17487 Less << |
NCT02304926 | Dyslipidemia | Not Applicable | Completed | - | - |
NCT02289430 | Healthy | Phase 1 | Completed | - | - |
NCT03169985 | Coronary Artery Disease | Phase 4 | Recruiting | December 31, 2023 | Korea, Republic of ... More >> Samsung Medical Center Recruiting Seoul, Korea, Republic of, 06351 Contact: Joo-Yong Hahn, MD, PhD ?? 82-2-3410-6653 ?? ichjy1@gmail.com ?? Contact: Joo Myung Lee, MD, MPH ?? 82-2-3410-1246 ?? drone80@hanmail.net Less << |
NCT02304926 | - | Completed | - | - | |
NCT02244944 | Nonalcoholic Fatty Liver Disea... More >>se (NAFLD) Less << | Phase 2 | Terminated(Failure to recruit) | - | United States, Kentucky ... More >> University of Kentucky Medical Center Lexington, Kentucky, United States, 40536 Less << |
NCT00634140 | Chronic Acalculous Cholecystit... More >>is Less << | Not Applicable | Withdrawn(Study was never init... More >>iated due to lack of funding support.) Less << | August 2009 | United States, Indiana ... More >> Indiana University Hospital Indianapolis, Indiana, United States, 46202 Less << |
NCT00651274 | Atherosclerosis ... More >> Hypercholesterolemia Coronary Heart Disease Less << | Phase 4 | Completed | - | - |
NCT01807078 | Coronary Artery Disease | Phase 4 | Unknown | December 2017 | Italy ... More >> Sapienza University Not yet recruiting Rome, Lazio, Italy, 00161 Contact: Francesco Pelliccia, MD ?? +39064997 ext 123 ?? f.pelliccia@mclink.it ?? Contact: Giuseppe Marazzi, MD ?? +39064997 ext 123 ?? md4151@mclink.it ?? Principal Investigator: Francesco Pelliccia, MD Less << |
NCT02588235 | Coronary Artery Disease | Phase 4 | Unknown | November 2017 | China, Shaanxi ... More >> Xijing Hospital, Fourth Military Medical University Recruiting Xi'an, Shaanxi, China, 710032 Contact: Dongdong Sun, M.D., Ph.D. Less << |
NCT00704535 | Primary Hypercholesterolemia|H... More >>omozygous Familial Hypercholesterolemia Less << | COMPLETED | 2025-04-08 | - | |
NCT02244944 | - | Terminated(Failure to recruit) | - | - | |
NCT02126137 | Chronic Hepatitis C | PHASE1 | UNKNOWN | 2025-03-16 | Department of Gastroenterology... More >>, Pontificia Universidad Católica de Chile, Santiago, Metropolitan, 8330024, Chile Less << |
NCT00762229 | Hypercholesterolemia | Not Applicable | Completed | - | United States, New York ... More >> Bronx VA Medical Center Bronx, New York, United States, 10468 Less << |
NCT02768545 | Hepatitis C | PHASE4 | UNKNOWN | 2025-06-16 | Departamento de Gastroenterolo... More >>gía, Pontificia Universidad Católica de Chile, Santiago, RM, 833-0024, Chile Less << |
NCT00794677 | Hypercholesterolemia | Phase 4 | Completed | - | United States, California ... More >> Cholesterol Research Center Berkeley, California, United States, 94705 Less << |
NCT00794677 | - | Completed | - | - | |
NCT02029625 | Dyslipidemia | Phase 1 | Completed | - | Korea, Republic of ... More >> Kyungpook National Hospital Jung-gu, Daegu, Korea, Republic of, 700-721 Less << |
NCT02548936 | Atherosclerosis | Early Phase 1 | Unknown | December 2016 | China, Beijing ... More >> Peking Union Medical College Hospital Beijing, Beijing, China, 100730 Less << |
NCT00762229 | - | Completed | - | - | |
NCT01849068 | Metabolic Syndrome X | Phase 3 | Completed | - | Canada ... More >> Laval University Quebec, Canada, G1V 0A6 Less << |
NCT01849068 | - | Completed | - | - | |
NCT03099278 | Chronic Hepatitis D | PHASE2 | UNKNOWN | 2025-10-17 | Ziauddin University Hospital, ... More >>Karachi, Sindh, 75600, Pakistan Less << |
NCT02772640 | Hypercholesterolemia | Phase 4 | Unknown | December 2016 | Poland ... More >> Cardiology Department, Dr. A. Jurasz University Hospital Recruiting Bydgoszcz, Kujawsko-Pomorskie, Poland, 85-094 Contact: Karolina Obońska, MD, PhD ?? +48 52 5854023 ?? kalaobonska@op.pl Less << |
NCT03105310 | Hepatitis D, Chronic | Phase 2 | Active, not recruiting | June 2017 | - |
NCT02971033 | Chronic Hepatitis C | Phase 2 | Recruiting | June 30, 2020 | United States, Illinois ... More >> Edward Hines Jr. VA Hospital, Hines, IL Recruiting Hines, Illinois, United States, 60141-5000 Contact: Susan L Uprichard, PhD ?? 708-202-8387 ext 25848 ?? Susan.Uprichard@va.gov ?? Principal Investigator: Susan L. Uprichard, PhD Less << |
NCT03531905 | Diabetes Diab... More >>etes Mellitus, Type 2 Cholesterolemia Less << | Phase 2 | Recruiting | May 2019 | United States, California ... More >> Clinical Trials Research Recruiting Lincoln, California, United States, 95648 United States, Florida FInlay Medical Research Recruiting Miami, Florida, United States, 33126 United States, Kentucky L-MARC Research Center Recruiting Louisville, Kentucky, United States, 40213 United States, Virginia Hampton Roads Center for Clinical Research Recruiting Suffolk, Virginia, United States, 23435 Less << |
NCT02682680 | Type 2 Diabetes Mellitus | Phase 4 | Unknown | December 2017 | Canada, Alberta ... More >> LMC Calgary Not yet recruiting Calgary, Alberta, Canada Contact: Akshay Jain, MD ?? 403-288-3224 ?? calgaryresearch@lmc.ca ?? Canada, Ontario LMC Barrie Recruiting Barrie, Ontario, Canada Contact: Hani Alasaad, MBBS ?? 705-737-0830 ?? barrieresearch@lmc.ca ?? LMC Brampton Recruiting Brampton, Ontario, Canada, L6S 0C9 Contact: Harpreet Bajaj, MBBS, MPH ?? 905-595-0560 ?? bramptonresearch@lmc.ca ?? LMC Etobicoke Recruiting Etobicoke, Ontario, Canada Contact: Hasnain Khandwala, MBBS ?? 416-645-1035 ?? etobicokeresearch@lmc.ca ?? LMC Markham Recruiting Markham, Ontario, Canada Contact: Nikhil Gupta, MBBS, MPH ?? 905-294-0800 ?? markhamresearch@lmc.ca ?? LMC Oakville Recruiting Oakville, Ontario, Canada Contact: David Twum-Barima, MB ChB, MSc ?? 905-337-0040 ?? oakvilleresearch@lmc.ca ?? LMC Thornhill Recruiting Thornhill, Ontario, Canada Contact: Ronald Goldenberg, MD ?? 905-763-8660 ?? thornhillresearch@lmc.ca ?? LMC Bayview Recruiting Toronto, Ontario, Canada Contact: Ronnie Aronson, MD ?? 416-645-2929 ?? torontoresearch@lmc.ca Less << |
NCT01384058 | Diabetes Mellitus Type 2 ... More >> Hypercholesterolemia Less << | Phase 4 | Completed | - | Germany ... More >> Institut für Stoffwechselforschung Frankfurt, Germany, 60322 Stephan Jacob, MD Villingen-.Schwenningen, Germany, 78048 Less << |
NCT02890992 | Hypercholesterolaemia | Phase 2 | Active, not recruiting | February 22, 2019 | United States, Missouri ... More >> Investigational Site Number 8400002 Saint Louis, Missouri, United States, 63110 United States, North Carolina Investigational Site Number 8400005 Charlotte, North Carolina, United States, 28204 United States, Ohio Investigational Site Number 8400001 Cincinnati, Ohio, United States, 45229 Canada Investigational Site Number 1240001 Quebec, Canada, G1V 4W2 Czechia Investigational Site Number 2030001 Brno, Czechia, 62500 Investigational Site Number 2030003 Praha 5 - Motol, Czechia, 15006 Investigational Site Number 2030002 Zlin, Czechia, 76275 France Investigational Site Number 2500001 Bron Cedex, France, 69677 Netherlands Investigational Site Number 5280001 Amsterdam, Netherlands, 1105 AZ Norway Investigational Site Number 5780001 Oslo, Norway, 0373 Russian Federation Investigational Site Number 6430001 Kemerovo, Russian Federation, 650002 Investigational Site Number 6430004 Saint-Petersburg, Russian Federation, 194100 South Africa Investigational Site Number 7100001 Parow, South Africa, 7500 Spain Investigational Site Number 7240004 A Coruna, Spain, 15001 Investigational Site Number 7240001 Madrid, Spain, 28009 Sweden Investigational Site Number 7520001 Stockholm, Sweden, 171 76 Less << |
NCT00079638 | Dyslipidemia ... More >>Coronary Heart Disease Atherosclerosis Stroke Diabetes Less << | Phase 4 | Completed | - | - |
NCT02755194 | - | Recruiting | September 2019 | Canada, Ontario ... More >> The Hospital for Sick Children Recruiting Toronto, Ontario, Canada, M5G1X8 Contact: Shinya Ito, MD, FRCPC ?? 416-813-7562 ?? shinya.ito@sickkids.ca Less << | |
NCT00120289 | Cardiovascular Diseases ... More >> Heart Diseases Cerebrovascular Accident Coronary Disease Atherosclerosis Myocardial Infarction Less << | Phase 3 | Terminated(AIM-HIGH was stoppe... More >>d on the recommendation of the DSMB because of lack of efficacy of niacin in preventing primary outcome events.) Less << | - | - |
NCT01660945 | Hypercholesterolemia | Phase 4 | Completed | - | Korea, Republic of ... More >> Gil Medical Center Incheon, Korea, Republic of, 405-760 Less << |
NCT03214211 | - | Not yet recruiting | June 30, 2022 | Korea, Republic of ... More >> Chonnam national university hospital Not yet recruiting Gwangju, Korea, Republic of Contact: Myung-Ho Jeong, Ph.D ?? ?? myungho@chollian.net Less << | |
NCT00701883 | Hyperlipidemia | Phase 2 | Completed | - | - |
NCT00120289 | - | Terminated(AIM-HIGH was stoppe... More >>d on the recommendation of the DSMB because of lack of efficacy of niacin in preventing primary outcome events.) Less << | - | - | |
NCT03449784 | - | Recruiting | May 1, 2041 | France ... More >> Uhmontpellier Recruiting Montpellier, France, 34295 Contact: cyril BREUKER ?? ?? c-breuker@chu-montpellier.fr Less << | |
NCT01252875 | Ischemic Stroke ... More >> Transient Ischemic Attack Atherosclerotic Stenosis Less << | Not Applicable | Recruiting | December 2019 | France ... More >> BICHAT HOSPITAL Departement of Neurology Recruiting Paris, France, 75018 Contact: Pierre AMARENCO, Pr, MD, PhD ?? +33(0)1 40 25 87 26 ?? Pierre.amarenco@bch.aphp.fr ?? Principal Investigator: Pierre AMARENCO, Pr, MD, PhD ?? ?? ?? BICHAT HOSPITAL Department of neurology and stroke center Recruiting Paris, France, 75018 Contact: Pierre Amarenco, MD ?? +33 (0) 1 40 25 87 26 ext 87 24 ?? pierre.amarenco@bch.aphp.fr Less << |
NCT01308203 | Coronary Artery Disease ... More >> Dyslipidemias Less << | Phase 4 | Terminated(Merck has decided t... More >>o discontinue all studies with extended-release niacin/laropiprant.because the HPS2-THRIVE did not meet its primary endpoint) Less << | - | Argentina ... More >> Hospital Italiano de Buenos Aires Buenos Aires, Argentina, C1181ACH Less << |
NCT01274559 | Primary Hypercholesterolemia ... More >> Mixed Dyslipidemia Less << | Phase 3 | Terminated(In HPS2-THRIVE, MK-... More >>0524A did not meet the primary efficacy objective and there was a significant increase in incidence of some types of non-fatal SAEs) Less << | - | - |
NCT01274559 | - | Terminated(In HPS2-THRIVE, MK-... More >>0524A did not meet the primary efficacy objective and there was a significant increase in incidence of some types of non-fatal SAEs) Less << | - | - | |
NCT03310671 | - | Recruiting | July 18, 2018 | Spain ... More >> Fernando Civeira Murillo Recruiting Zaragoza, Spain, 50009 Contact: Victoria MARCO BENEDí, RD ?? 976765500 ext 2895 ?? vmarcobenedi@gmail.com Less << | |
NCT02941848 | Primary Hypercholesterolemia | Phase 1 | Completed | - | - |
NCT00679237 | Coronary Heart Disease | Not Applicable | Active, not recruiting | December 2024 | Norway ... More >> Sorlandet Hospital Arendal, Norway Less << |
NCT02642159 | Dyslipidemia | Phase 4 | Completed | - | - |
NCT02055976 | Hypercholesterolemia | Phase 2 | Completed | - | Japan ... More >> Maebashi Hirosegawa Clinic Maebashi, Gunma, Japan, 371-0022 Yokohama Minoru Clinic Yokohama, Kanagawa, Japan, 232-0064 Heishinkai Medical Group Incorporated OCROM Clinic Suita, Osaka, Japan, 565-0853 Meiwa Hospital Chiyoda-ku, Tokyo, Japan, 101-0041 Tokyo-Eki Center-building Clinic Chuo-ku, Tokyo, Japan, 103-0027 Heishinkai Medical Group Incorporated ToCROM Clinic Shinjuku-ku, Tokyo, Japan, 160-0022 Clinical Research Hospital Tokyo Shinjuku-ku, Tokyo, Japan, 162-0053 Oda Clinic Shinjuku-ku, Tokyo, Japan, 169-0072 Sekino Hospital Toshima-ku, Tokyo, Japan, 171-0014 Less << |
NCT00655265 | Familial Hypercholesterolemia | Phase 4 | Completed | - | France ... More >> Service d'Endocrinologie, Metabolisme Prevention des Maladies Cardio-Vasculaires Paris Cedex, France Germany Kardiologie Marburg, Germany Netherlands Academic Medical Centre Amsterdam, Netherlands University Medical Centre Nijmegen, Netherlands University Medical Centre Utrecht, Netherlands TweeSteden Ziekenhius Waalwijk, Netherlands Sweden Centre for Metabolism and Endocrinology Huddinge, Sweden United Kingdom Department of Medicine, University of Manchester Manchester, United Kingdom Less << |
NCT02642159 | - | Completed | - | - | |
NCT01477944 | - | Completed | - | - | |
NCT02942602 | Hyperlipidemia | Not Applicable | Completed | - | Korea, Republic of ... More >> Division of Cardiology, Department of Internal Medicine, Seoul, Korea, Republic of, 03722 Less << |
NCT00359281 | Healthy | Phase 2 | Completed | - | United States, Pennsylvania ... More >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less << |
NCT03433755 | Primary Hypercholesterolemia ... More >> Mixed Dyslipidemia Less << | Phase 3 | Not yet recruiting | August 25, 2020 | - |
NCT01516879 | - | Completed | - | - | |
NCT01948648 | Sitosterolemia | Not Applicable | Recruiting | December 31, 2019 | Canada, Manitoba ... More >> Richardson Center for Functional Foods and Nutraceuticals Recruiting Winnipeg, Manitoba, Canada Contact: Semone B Myrie, PhD ?? 204-272-1555 ?? myrie@cc.umanitoba.ca ?? Contact: Peter J Jones, PhD ?? 204-474-8883 ?? Peter.Jones@umanitoba.ca ?? Sub-Investigator: Semone B Myrie, PhD ?? ?? ?? Principal Investigator: Peter J Jones, PhD ?? ?? ?? Sub-Investigator: David Mymim, PhD ?? ?? ?? Sub-Investigator: Taback Shayne, PHD Less << |
NCT00090168 | Hypercholesterolemia ... More >> Atherosclerotic Disease Coronary Disease Less << | Phase 3 | Completed | - | - |
NCT01516879 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT01420328 | Inflammation | Phase 3 | Unknown | December 2013 | United States, New York ... More >> Diabetes Endocrinology Center of WNY Buffalo, New York, United States, 14209 Less << |
NCT03549260 | LDL Cholesterol | Phase 2 | Active, not recruiting | November 30, 2018 | United States, Indiana ... More >> Midwest Institute For Clinical Research Indianapolis, Indiana, United States, 46260 United States, Kentucky Louisville Metabolic and Atherosclerosis Research Center Louisville, Kentucky, United States, 40213 United States, Ohio Sterling Research Group Cincinnati, Ohio, United States, 45219 The Lindner Research Center Cincinnati, Ohio, United States, 45219 Metabolic & Atherosclerosis Research Center (MARC) Cincinnati, Ohio, United States, 45227 Less << |
NCT00952770 | Coronary Artery Disease | Phase 4 | Unknown | - | Korea, Republic of ... More >> Chungnam National University Hospital Recruiting Daejeon, Korea, Republic of Contact: Jae-Hyeong Park, MD, PhD ?? 82-42-280-7167 ?? jaehpark@cnuh.co.kr Less << |
NCT01070966 | - | Completed | - | - | |
NCT00724477 | - | Completed | - | - | |
NCT00359281 | - | Completed | - | - | |
NCT02205775 | Stable Coronary Artery Disease... More >> Undergoing PCI Less << | Phase 3 | Terminated(difficult recruitme... More >>nt) Less << | - | Italy ... More >> SS. Annunziata Hospital Chieti, CH, Italy, 66100 Fondazione IRCCS Policlinico S. Matteo Pavia, PV, Italy, 27100 A.O. S. Anna e S. Sebastiano - II Università di Napoli Caserta, Italy, 81100 Azienda ASL 6 - P. Ospedaliero Livorno Livorno, Italy, 57100 Ospedale Civile G. Fornaroli Magenta, Italy, 20013 Azienda Ospedaliera - Ospedale San Paolo Milano, Italy, 20142 Less << |
NCT01070966 | - | Completed | - | - | |
NCT01112423 | Dyslipidemia | Phase 2 | Completed | - | United States, Arkansas ... More >> Osborne Research Center Little Rock, Arkansas, United States, 72201 United States, Kansas Pra International Lenexa, Kansas, United States, 66219 United States, Ohio Sterling Research Grp, Ltd. Cincinnati, Ohio, United States, 45219 United States, Texas Cetero Research - San Antonio San Antonio, Texas, United States, 78229 United States, Virginia National Clinical Research - Norfolk, Inc. Norfolk, Virginia, United States, 23502 National Clinical Research - Richmond, Inc. Richmond, Virginia, United States, 23294 Australia, Queensland Local Institution Brisbane, Queensland, Australia, 4021 Canada, Manitoba Local Institution Winnipeg, Manitoba, Canada, R2V 4W3 Canada, Newfoundland and Labrador Local Institution Mount Pearl, Newfoundland and Labrador, Canada, A1N 1W7 Canada, Ontario Local Institution London, Ontario, Canada, N6A 5R8 Canada, Quebec Local Institution Drummondville, Quebec, Canada, J2B 7T1 Local Institution Montreal, Quebec, Canada, H3J 2V5 Less << |
NCT00724477 | - | Completed | - | - | |
NCT00548145 | - | Terminated | - | - | |
NCT00548145 | Alzheimer Disease ... More >> Hypercholesterolemia Less << | Not Applicable | Terminated | - | Japan ... More >> Osaka University Hospital Suita, Osaka, Japan, 565-0871 Less << |
NCT00738972 | Hypertension | Phase 3 | Terminated(Study terminated ea... More >>rly due to sample size, not possible to perform further statistical analysis.) Less << | - | - |
NCT00738972 | - | Terminated(Study terminated ea... More >>rly due to sample size, not possible to perform further statistical analysis.) Less << | - | - | |
NCT00092807 | Lipid Metabolism, Inborn Error... More >>s Heart Disease Less << | Phase 3 | Completed | - | - |
NCT00559962 | Hyperlipidemia | Phase 2 | Completed | - | United States, California ... More >> Scripps Clinic San Diego, California, United States, 92128 Radiant Research Santa Rosa, California, United States, 95405 United States, District of Columbia MedStar Research Institute Washington, District of Columbia, United States, 20003 United States, Illinois Radiant Research Chicago, Illinois, United States, 60610 United States, Iowa University of Iowa Iowa City, Iowa, United States, 52242 United States, Kentucky LMARC Louisville, Kentucky, United States, 40213 United States, Maine Maine Research Associates Auburn, Maine, United States, 04210 United States, Maryland Health Trends Research Baltimore, Maryland, United States, 21209 Johns Hopkins Baltimore, Maryland, United States, 21287 United States, Missouri Washington Univ. School of Medicine Saint Louis, Missouri, United States, 63110 United States, Ohio Sterling Research Group Cincinnati, Ohio, United States, 45219 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 Clinical Trial Network Houston, Texas, United States, 77074 dgd Research San Antonio, Texas, United States, 78229 Less << |
NCT00092820 | Lipid Metabolism, Inborn Error... More >>s Heart Disease Less << | Phase 3 | Completed | - | - |
NCT00132717 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT02767362 | Endometrial Cancer | Early Phase 1 | Recruiting | November 2020 | United States, North Carolina ... More >> University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center Recruiting Chapel Hill, North Carolina, United States, 27599 Contact: Leslie Clark, MD ?? 919-843-7572 ?? leslie_clark@med.unc.edu ?? Principal Investigator: Leslie Clark, MD Less << |
NCT01890889 | Cholesterol H... More >>yperlipidemia Hypercholesteremia Less << | Not Applicable | Unknown | December 2013 | United States, Texas ... More >> Integrative Health Technologies Recruiting San Antonio, Texas, United States, 78209 Contact: Patricia l Keith, BBA ?? 210-824-4200 ?? hmrcenterstudy@gmail.com ?? Contact: Mike E Gale, BS ?? 210-824-4200 ?? hmrcenterstudy@gmail.com ?? Sub-Investigator: Patricia L Keith, BBA ?? ?? ?? Sub-Investigator: Samuel C Keith, BBA ?? ?? ?? Sub-Investigator: Joel A Michalek, PhD ?? ?? ?? Sub-Investigator: Harry A Croft, MD Less << |
NCT01218204 | Dyslipidaemias | Phase 2 | Completed | - | - |
NCT01218204 | - | Completed | - | - | |
NCT00687076 | Peripheral Arterial Disease | Phase 4 | Completed | - | United States, Texas ... More >> Baylor College of Medicine Houston, Texas, United States, 77030 Less << |
NCT00559962 | - | Completed | - | - | |
NCT00449410 | Atrial Fibrillation ... More >> Neuropsychology Magnetic Resonance Imaging Inflammation Hemostasis Less << | Phase 4 | Completed | - | Netherlands ... More >> Gheorghe AM Pop Nijmegen, Netherlands, 6500 HB Less << |
NCT03110432 | - | Recruiting | February 16, 2021 | Germany ... More >> Medizinische Klinik und Poliklinik III Recruiting Dresden, Germany Contact: Andreas Birkenfeld, MD Less << | |
NCT01890967 | Hypercholesterolemia | Phase 2 | Completed | - | - |
NCT00687076 | - | Completed | - | - | |
NCT00442897 | Hypercholesterolemia | Phase 4 | Completed | - | - |
NCT01890967 | - | Completed | - | - | |
NCT02260648 | Hypercholesterolemia | Phase 3 | Terminated(Study termination d... More >>ue to insufficient efficacy.) Less << | - | Japan ... More >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Hyogo, Japan, 650-0021 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Ibaragi, Japan, 311-3516 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Ibaraki, Japan, 311-4153 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Kyoto, Japan, 6150035 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Osaka, Japan, 530-0001 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Saitama, Japan, 350-1305 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Shizuoka, Japan, 424-0855 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Tokyo, Japan, 103-0028 Less << |
NCT01587235 | Dyslipidemia | Phase 4 | Withdrawn | May 2014 | - |
NCT01043380 | Hypercholesterolemia ... More >> Coronary Artery Disease Less << | Phase 4 | Completed | - | Japan ... More >> Kumamoto University Kumamoto, Japan, 8608556 Less << |
NCT03204799 | - | Recruiting | December 16, 2018 | Korea, Republic of ... More >> Yonsei University College of Medicine, Department of Internal Medicine, Division of Endocrinology, Severance Hospital, Diabetes center Recruiting Seoul, Korea, Republic of, 03722 Contact: Yong-ho Lee, M.D., Ph.D. ?? 82-2-2228-1943 ?? yholee@yuhs.ac Less << | |
NCT00461630 | Cardiovascular Disease ... More >> Peripheral Arterial Disease Diabetes Mellitus Coronary Heart Disease Less << | Phase 3 | Completed | - | United Kingdom ... More >> Clinical Trial Service Unit, University of Oxford Oxford, United Kingdom, OX3 7LF Less << |
NCT02260648 | - | Terminated(Study termination d... More >>ue to insufficient efficacy.) Less << | - | - | |
NCT00461630 | - | Completed | - | - | |
NCT00433823 | Coronary Heart Disease ... More >> Diabetes Mellitus Non-Coronary Atherosclerotic Disease Hypercholesterolemia Less << | Phase 4 | Unknown | - | Turkey ... More >> Bolu Izzet Baysal School of Medicine Recruiting Bolu, Turkey, 14280 Contact: Mustafa Kanat, MD ?? +905385448782 ?? mustafa.kanat@gmail.com Less << |
NCT00462748 | - | Completed | - | - | |
NCT02460159 | Hypercholesterolemia ... More >> Heterozygous Familial Hypercholesterolemia Less << | Phase 3 | Completed | - | - |
NCT00408057 | - | Completed | - | Canada, Ontario ... More >> St. MIchael's Hospital Toronto, Ontario, Canada, m5g 2p9 Less << | |
NCT00442897 | - | Completed | - | - | |
NCT03532854 | Healthy Male Volunteers | Phase 1 | Not yet recruiting | September 18, 2018 | Korea, Republic of ... More >> LG chem Not yet recruiting Seoul, Gangseo-Gu, Korea, Republic of, 07795 Contact: Subin Lee ?? 02-6987-4153 ?? leesubin@lgchem.com Less << |
NCT00462748 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00738296 | Cardiovascular Diseases | Phase 4 | Completed | - | - |
NCT02460159 | - | Completed | - | - | |
NCT00110435 | Type 2 Diabetes Mellitus ... More >> Hypercholesterolemia Less << | Phase 3 | Completed | - | - |
NCT03355027 | Atherosclerosis ... More >> Cardiovascular Diseases Less << | Not Applicable | Recruiting | May 8, 2019 | United Kingdom ... More >> Addenbrooke's Hospital Recruiting Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ Contact: Paul Cacciottolo ?? 01223256653 ?? pjc99@medschl.cam.ac.uk ?? Principal Investigator: Joseph Cheriyan, MBChB, MA, FRCP Less << |
NCT00496730 | - | Completed | - | - | |
NCT02550288 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT01763866 | Hyperlipidemia | Phase 3 | Completed | - | - |
NCT02550288 | - | Completed | - | - | |
NCT00651560 | Hyperlipidemia | Phase 3 | Completed | - | - |
NCT00090298 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT03750760 | Myocardial Infarction ... More >> Dyslipidemias Less << | Phase 4 | Not yet recruiting | July 2019 | United Kingdom ... More >> Royal Devon & Exeter Hospital Not yet recruiting Exeter, Devon, United Kingdom, EX2 5DW Contact: Andrew Sharp, MBChB, MRCP, MD ?? ?? ?? The Royal Bournemouth General Hospital Not yet recruiting Bournemouth, Dorset, United Kingdom, BH7 7DW Contact: Terry Levy, BSc, MB ChB, FRCP ?? ?? ?? East Sussex Healthcare NHS Trust Not yet recruiting Saint Leonards-on-Sea, East Sussex, United Kingdom, TN37 7PT Contact: Robert Gerber, MBBS ?? ?? ?? Basildon Hospital Not yet recruiting Basildon, Essex, United Kingdom, SS16 5NL Contact: Rajesh Aggarwal, MB ChB, FRCP (London), MD ?? ?? ?? St Mary's Hospital Not yet recruiting London, Greater London, United Kingdom, W2 1NY Contact: Jamil Mayet, MBChB, MD, FESC, FACC, FRC ?? ?? ?? Queen Alexandra Hospital Not yet recruiting Portsmouth, Hampshire, United Kingdom, PO6 3LY Contact: Huw Griffiths, MB BS (Hons), MD, FRCP ?? ?? ?? Southampton General Hospital Not yet recruiting Southampton, Hampshire, United Kingdom, SO16 6YD Contact: Nick Curzen, BM(Hons), PhD, FRCP ?? ?? ?? Northwick Park Hospital Not yet recruiting Harrow, Middlesex, United Kingdom, HA1 3UJ Contact: Ahmed Elghamaz, MB BCh MRCP ?? ?? ?? Hull Royal Infirmary Not yet recruiting Hull, North Humberside, United Kingdom, HU3 2JZ Contact: Richard Oliver, MB BS, RFCP DM, FESC ?? ?? ?? Queens Medical Centre Not yet recruiting Nottingham, Nottinghamshire, United Kingdom, NG7 2UH Contact: Shahnaz Jamil-Copley, MBChB, MRCP, PhD ?? ?? ?? St Peters Hospital Not yet recruiting Chertsey, Surrey, United Kingdom, KT16 0PZ Contact: Sumeet Sharma, MD, MRCP, CCT ?? ?? ?? East Surrey Hospital Not yet recruiting Redhill, Surrey, United Kingdom, RH1 5RH Contact: Rashid Iqbal, MSc, MRCP, MRCPI ?? ?? ?? Freeman Hospital Not yet recruiting Newcastle Upon Tyne, Tyne And Wear, United Kingdom, NE7 7DN Contact: Vijay Kunadian, MBBS, MD, FRCP, FACC, FESC ?? ?? ?? Queen Elizabeth Medical Centre Not yet recruiting Birmingham, West Midlands, United Kingdom, B15 2TH Contact: John Townend, MBChB, MD, FRCP, FESC ?? ?? ?? City Hospital Not yet recruiting Birmingham, West Midlands, United Kingdom, B18 7QH Contact: Derek Connolly, MBChB, PhD, FRCP ?? ?? ?? Worchestershire Royal Hospital Not yet recruiting Worcester, Worcestershire, United Kingdom, WR5 1DD Contact: Jasper Trevelyan, MB ChB ?? ?? ?? Northern General Hospital Not yet recruiting Sheffield, Yorkshire, United Kingdom, S5 7AU Contact: Robert Storey, BM, DM, FRCP, FESC Less << |
NCT00541697 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT00440154 | Hypercholesterolemia | Phase 2 | Completed | - | Chile ... More >> Sanofi-Aventis Administrative Office Santiago, Chile Hungary Sanofi-Aventis Administrative Office Budapest, Hungary Korea, Republic of Sanofi-Aventis Administrative Office Seoul, Korea, Republic of Mexico Sanofi-Aventis Administrative Office Mexico, Mexico Russian Federation Sanofi-Aventis Administrative Office Moscow, Russian Federation Turkey Sanofi-Aventis Administrative Office Istanbul, Turkey Less << |
NCT00496730 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00587678 | Peripheral Artery Disease | Not Applicable | Completed | - | United States, Virginia ... More >> University of Virgina Health System Charlottesville, Virginia, United States, 22908 Less << |
NCT00587678 | - | Completed | - | - | |
NCT02741245 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT01520077 | Alopecia Areata | Phase 1 | Completed | - | United States, Florida ... More >> University of Miami Miami, Florida, United States, 33136 Less << |
NCT02741245 | - | Completed | - | - | |
NCT02445352 | Primary Hypercholesterolemia | Phase 3 | Completed | - | Korea, Republic of ... More >> Severance Hospital Seodaemun-gu, Seoul, Korea, Republic of, 120-752 Less << |
NCT00092716 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00092586 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT03543774 | Hypercholesterolemia ... More >> Chronic Kidney Diseases Less << | Phase 4 | Recruiting | September 15, 2019 | Vietnam ... More >> Hue University of Medicine and Pharmacy Recruiting Hue, Thua Thien Hue, Vietnam, 0234 Contact: Nguyen Thanh Thao ?? 84.234.3822873 ?? hcmp@huemed-univ.edu.vn ?? Contact: Nguyen Thanh Thao ?? 84.234.3822873 ?? thaonrad@gmail.com ?? Principal Investigator: Duong Thi Ngoc Lan, Master ?? ?? ?? Sub-Investigator: Le Van An, A/Professor Less << |
NCT01763866 | - | Completed | - | - | |
NCT00413972 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00413972 | - | Completed | - | - | |
NCT02227784 | Hyperlipidemia | Phase 3 | Terminated(Study termination d... More >>ue to program termination.) Less << | - | - |
NCT00157911 | Hypercholerolemia | Phase 3 | Completed | - | - |
NCT00092898 | Lipid Metabolism, Inborn Error... More >>s Heart Disease Less << | Phase 3 | Completed | - | - |
NCT02451098 | Hyperlipidemia | Phase 3 | Completed | - | Korea, Republic of ... More >> The catholic university of korea seoul st. Mary's hospital Seoul, Korea, Republic of Less << |
NCT00092664 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00092599 | Hypercholesterolemia ... More >> Coronary Disease Less << | Phase 3 | Completed | - | - |
NCT01077830 | - | Completed | - | - | |
NCT00092612 | Hypercholesterolemia ... More >> Coronary Disease Less << | Phase 3 | Completed | - | - |
NCT00092625 | Hypercholesterolemia ... More >> Coronary Disease Less << | Phase 3 | Completed | - | - |
NCT00092638 | Hypercholesterolemia ... More >> Coronary Disease Less << | Phase 3 | Completed | - | - |
NCT02227784 | - | Terminated(Study termination d... More >>ue to program termination.) Less << | - | - | |
NCT00093899 | Hyperlipidemia ... More >> Hypercholesterolemia Hypertriglyceridemia Less << | Phase 3 | Completed | - | - |
NCT00566267 | Hyperlipidemia | Phase 2 Phase 3 | Completed | - | - |
NCT00762164 | Hypercholesterolemia | Phase 4 | Completed | - | United States, New York ... More >> Bronx VA Medical Center Bronx, New York, United States, 10468 Less << |
NCT00762164 | - | Completed | - | - | |
NCT01414192 | - | Completed | - | - | |
NCT01414192 | - | Completed | - | - | |
NCT01857843 | Acute Coronary Syndrome | Phase 4 | Completed | - | Korea, Republic of ... More >> Severance Hospital Seoul, Korea, Republic of, 120-752 Less << |
NCT01730040 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT00092677 | Aortic Stenosis | Phase 3 | Completed | - | - |
NCT01730040 | - | Completed | - | - | |
NCT02547402 | Acute Kidney Injury | Phase 1 | Completed | - | United States, Michigan ... More >> Jasper Clinical Research & Development, Inc. Kalamazoo, Michigan, United States, 49007 Less << |
NCT01154036 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT03768427 | Hypercholesterolemia | Phase 3 | Not yet recruiting | January 29, 2021 | - |
NCT00092677 | - | Completed | - | - | |
NCT01154036 | - | Completed | - | - | |
NCT02730689 | Healthy Volunteers | Phase 1 | Completed | - | - |
NCT00092560 | Hypercholesterolemia ... More >> Hypertriglyceridemia Less << | Phase 3 | Completed | - | - |
NCT02534376 | Prostate Cancer | Early Phase 1 | Recruiting | February 2020 | United States, California ... More >> Cedars Sinai Medical Center Recruiting Los Angeles, California, United States, 90048 Contact: Jenny Park, MPH ?? 310-423-8762 ?? jenny.park@cshs.org ?? Principal Investigator: Hyung L Kim, MD Less << |
NCT02501200 | Healthy | Phase 1 | Completed | - | - |
NCT00395603 | Cardiovascular Diseases ... More >> Diabetes Mellitus Less << | Phase 3 | Terminated(This study was term... More >>inated early due to poor recruitment.) Less << | - | - |
NCT01077830 | - | Completed | - | - | |
NCT02461004 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... More >> The Korea University Anam Hospital Seoul, Korea, Republic of Less << |
NCT02584504 | Hypercholesterolemia | Phase 3 | Completed | - | Japan ... More >> Investigational Site Number 392028 Ageo-Shi, Japan Investigational Site Number 392007 Chuo-Ku, Japan Investigational Site Number 392029 Chuo-Ku, Japan Investigational Site Number 392014 Fukui-Shi, Japan Investigational Site Number 392023 Hachioji-Shi, Japan Investigational Site Number 392013 Itoshima-Shi, Japan Investigational Site Number 392010 Kanazawa-Shi, Japan Investigational Site Number 392024 Kasuga-Shi, Japan Investigational Site Number 392004 Kawanishi-Shi, Japan Investigational Site Number 392015 Kitakyushu-Shi, Japan Investigational Site Number 392005 Komatsu-Shi, Japan Investigational Site Number 392032 Matsudo-Shi, Japan Investigational Site Number 392017 Matsumoto-Shi, Japan Investigational Site Number 392003 Mito-Shi, Japan Investigational Site Number 392018 Morioka-Shi, Japan Investigational Site Number 392009 Moriya-Shi, Japan Investigational Site Number 392006 Nagoya-Shi, Japan Investigational Site Number 392011 Nagoya-Shi, Japan Investigational Site Number 392019 Nagoya-Shi, Japan Investigational Site Number 392025 Nagoya-Shi, Japan Investigational Site Number 392027 Osaka-Shi, Japan Investigational Site Number 392030 Sakura-Shi, Japan Investigational Site Number 392016 Shinagawa-Ku, Japan Investigational Site Number 392001 Shinjuku-Ku, Japan Investigational Site Number 392008 Shinjuku-Ku, Japan Investigational Site Number 392012 Shizuoka-Shi, Japan Investigational Site Number 392002 Suita-Shi, Japan Investigational Site Number 392031 Suita-Shi, Japan Investigational Site Number 392020 Toyonaka-Shi, Japan Investigational Site Number 392022 Yao-Shi, Japan Less << |
NCT01047683 | Hypertriglyceridemia | Phase 3 | Completed | - | - |
NCT01047501 | Hypertriglyceridemia | Phase 3 | Completed | - | - |
NCT02584504 | - | Completed | - | - | |
NCT01492361 | Cardiovascular Diseases | Phase 3 | Completed | - | - |
NCT02378064 | Inflammation Plaque, Atheroscl... More >>erotic Coronary Disease Renin-Angiotensin System Less << | Phase 4 | Completed | - | Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less << |
NCT02023879 | Hypercholesterolemia | Phase 3 | Completed | - | - |
NCT03430284 | Diabetes Mellitus, Type 2 | Phase 4 | Recruiting | December 31, 2020 | China, Shandong ... More >> Shandong Provincial Hospital Not yet recruiting Jinan, Shandong, China, 250021 Contact: Shanshan Shao ?? +8653168776094 ?? shaoshanshan11@126.com ?? Shandong Provincial Hospital Recruiting Jinan, Shandong, China Less << |
NCT03510884 | Hypercholesterolaemia | Phase 3 | Recruiting | March 2022 | - |
NCT01666067 | Hypercholesterolemia | Phase 4 | Completed | - | Korea, Republic of ... More >> Gil Medical Center Incheon, Korea, Republic of, 405-760 Less << |
NCT02023879 | - | Completed | - | - | |
NCT01266876 | - | Completed | - | - | |
NCT02984982 | Hypercholesterolemia ... More >> Acute Coronary Syndrome Less << | Phase 4 | Completed | - | Japan ... More >> Investigational Site Number 392026 Bunkyoku-ku, Japan Investigational Site Number 392022 Chiyoda-ku, Japan Investigational Site Number 392032 Fujisawa-shi, Japan Investigational Site Number 392004 Fukui-shi, Japan Investigational Site Number 392007 Fukuoka-shi, Japan Investigational Site Number 392048 Fukuoka-shi, Japan Investigational Site Number 392008 Gifu-shi, Japan Investigational Site Number 392039 Hiroshima-shi, Japan Investigational Site Number 392028 Isehara-shi, Japan Investigational Site Number 392036 Itabashi-ku, Japan Investigational Site Number 392037 Itabashi-ku, Japan Investigational Site Number 392024 Izumisano-shi, Japan Investigational Site Number 392013 Izunokuni-shi, Japan Investigational Site Number 392020 Kawaguchi-shi, Japan Investigational Site Number 392041 Kisarazu-shi, Japan Investigational Site Number 392009 Kitakyushu-shi, Japan Investigational Site Number 392034 Kitakyushu-shi, Japan Investigational Site Number 392044 Kochi-shi, Japan Investigational Site Number 392002 Kumamoto-shi, Japan Investigational Site Number 392011 Kumamoto-shi, Japan Investigational Site Number 392003 Kurashiki-shi, Japan Investigational Site Number 392018 Matsuyama-shi, Japan Investigational Site Number 392021 Morioka-shi, Japan Investigational Site Number 392017 Nagakute-shi, Aichi, Japan Investigational Site Number 392047 Nagaoka-shi, Japan Investigational Site Number 392038 Nagoya-shi, Japan Investigational Site Number 392042 Nagoya-shi, Japan Investigational Site Number 392033 Okayama-shi, Japan Investigational Site Number 392006 Osaka-shi, Japan Investigational Site Number 392010 Osaka-shi, Japan Investigational Site Number 392045 Osaka-shi, Japan Investigational Site Number 392046 Osaka-shi, Japan Investigational Site Number 392015 Sagamihara-shi, Japan Investigational Site Number 392019 Sakai-shi, Japan Investigational Site Number 392035 Sapporo-shi, Japan Investigational Site Number 392001 Tenri-shi, Japan Investigational Site Number 392016 Toyoake-shi, Japan Investigational Site Number 392025 Tsukuba-shi, Japan Investigational Site Number 392040 Tsukuba-shi, Japan Investigational Site Number 392005 Wakayama-shi, Japan Investigational Site Number 392027 Yokohama-shi, Japan Investigational Site Number 392043 Yokohama-shi, Japan Less << |
NCT03510715 | Hypercholesterolemia | Phase 3 | Recruiting | June 2020 | United States, California ... More >> Investigational Site Number 8400004 Recruiting Los Angeles, California, United States, 90027 Austria Investigational Site Number 0400001 Recruiting Wien, Austria, 1090 Brazil Investigational Site Number 0760001 Recruiting Sao Paulo, Brazil, 05403-000 Canada Investigational Site Number 1240002 Recruiting Montreal, Canada, H3T 1C5 Investigational Site Number 1240001 Recruiting Quebec, Canada, G1V 4W2 Denmark Investigational Site Number 2080001 Recruiting Viborg, Denmark, 8800 France Investigational Site Number 2500001 Recruiting Bron Cedex, France, 69677 Italy Investigational Site Number 3800001 Recruiting Palermo, Italy, 90127 Mexico Investigational Site Number 4840006 Recruiting Oaxaca, Mexico, 68000 Netherlands Investigational Site Number 5280001 Recruiting Amsterdam, Netherlands, 1105 AZ Norway Investigational Site Number 5780001 Recruiting Oslo, Norway, 0373 Russian Federation Investigational Site Number 6430002 Recruiting Kemerovo, Russian Federation, 650002 Slovenia Investigational Site Number 7050001 Recruiting Ljubljana, Slovenia, 1000 Spain Investigational Site Number 7240001 Recruiting A Coruna, Spain, 15001 Taiwan Investigational Site Number 1580001 Recruiting Taipei, Taiwan, 112 Turkey Investigational Site Number 7920002 Recruiting Ankara, Turkey, 06500 Investigational Site Number 7920001 Recruiting Izmir, Turkey, 35040 Less << |
NCT01266876 | Hypercholesterolemia | Phase 2 | Completed | - | - |
NCT00099684 | HIV Infections | COMPLETED | 2025-05-07 | University of Alabama at Birmi... More >>ngham, Birmingham, Alabama, 35924-2050, United States|UCLA School of Medicine, Los Angeles, California, 77555-0435, United States|University of Southern California, Los Angeles, California, 90033-1079, United States|University of California, San Diego Antiviral Research Center, San Diego, California, 92103, United States|San Francisco General Hospital, San Francisco, California, 94110, United States|San Mateo County AIDS Program, Stanford, California, 94305-5107, United States|Santa Clara Valley Medical Center, Stanford, California, 94305-5107, United States|Stanford University, Stanford, California, 94305-5107, United States|Willow Clinic, Stanford, California, 94305-5107, United States|Georgetown University Medical Center, Washington, District of Columbia, 20007, United States|University of Miami, Miami, Florida, 33136-1013, United States|University of Hawaii, Honolulu, Hawaii, 96816-2396, United States|Feinberg School of Medicine, HIV/ACTU, Chicago, 60611-3015, Illinois, 60611-3015, United States|Rush-Presbyterian/St. Lukes (Chicago), Chicago, Illinois, 60611-3015, United States|Cook County Hospital Core Center, Chicago, Illinois, 60612, United States|Indiana University Hospital, Indianapolis, Indiana, 46202-5250, United States|Wishard Hospital, Indianapolis, Indiana, 46202, United States|University of Minnesota, Minneapolis, Minnesota, 55455-0392, United States|Nebraska Health System, Omaha, Nebraska, 68198-5130, United States|SUNY - Buffalo (Rochester), Buffalo, New York, 14215, United States|Beth Israel Medical Center, New York, New York, 10003, United States|Chelsea Clinic, New York, New York, 10011, United States|NYU/Bellevue, New York, New York, 10016-6481, United States|The Cornell Clinical Trials Unit, New York, New York, 10021, United States|Columbia University, New York, New York, 10032-3784, United States|Community Health Network, Inc., Rochester, New York, 14642-0001, United States|University of Rochester Medical Center, Rochester, New York, 14642-0001, United States|Duke University Medical Center, Durham, North Carolina, United States|University of Cincinnati, Cincinnati, Ohio, 45267-0405, United States|MetroHealth Medical Center, Cleveland, Ohio, 44109-1998, United States|Ohio State University, Columbus, Ohio, 43210, United States|Presbyterian Medical Center - Univ. of PA, Philadelphia, Pennsylvania, 19104, United States|University of Pennsylvania, Philadelphia, Philadelphia, Pennsylvania, 19104, United States|University of Pittsburgh, Pittsburgh, Pennsylvania, 15213-2582, United States|Rhode Island Hospital, Providence, Rhode Island, 02906, United States|Stanley Street Treatment and Resource, Providence, Rhode Island, 02906, United States|The Miriam Hospital, Providence, Rhode Island, 02906, United States|Comprehensive Care Clinic, Nashville, Tennessee, 37203, United States|Dallas VA Medical Center, Dallas, Texas, 75235-9173, United States|University of Texas, Galveston, Galveston, Texas, 77555-0435, United States|University of Washington (Seattle), Seattle, Washington, 98104, United States|University of Puerto Rico, San Juan, 00936-5067, Puerto Rico Less << | |
NCT01381679 | Hypercholesterolemia | COMPLETED | 2025-12-10 | - | |
NCT00485121 | Metabolic Syndrome|Obesity|Cor... More >>onary Artery Disease Less << | COMPLETED | 2025-04-09 | Partners Research, Brampton, O... More >>ntario, L6V 1B4, Canada Less << | |
NCT00376246 | Endothelial Dysfunction | PHASE4 | COMPLETED | 2025-04-08 | - |
NCT01068093 | Coronary Artery Disease | PHASE4 | UNKNOWN | 2025-10-15 | Yokohama City University Medic... More >>al Center, Yokohama, Kanagawa, 231-0045, Japan Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.44mL 0.49mL 0.24mL |
12.21mL 2.44mL 1.22mL |
24.42mL 4.88mL 2.44mL |
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Dissolving Methods |
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
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