99.5%(GC)| A1455226|Formula:C9H7NO|Molecular Weight:145.1650000+ products instock " />

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Chemical Structure| 148-24-3 Chemical Structure| 148-24-3
Chemical Structure| 148-24-3

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CAS No.: 148-24-3

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8-Hydroxyquinoline inhibits RNA synthesis and acts as a fungicide against Trichophyton mentagrophytes, Myrothecium verrucaria and Trichoderma viride, it's also a monoprotic bidentate chelating agent and dye.

Synonyms: 8-Quinolinol; 8-Oxychinolin; NSC 2039

4.5 *For Research Use Only !

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Product Details of 8-Hydroxyquinoline

CAS No. :148-24-3
Formula : C9H7NO
M.W : 145.16
SMILES Code : OC1=C2N=CC=CC2=CC=C1
Synonyms :
8-Quinolinol; 8-Oxychinolin; NSC 2039
MDL No. :MFCD00006807
InChI Key :MCJGNVYPOGVAJF-UHFFFAOYSA-N
Pubchem ID :1923

Safety of 8-Hydroxyquinoline

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H317-H318-H360-H410
Precautionary Statements:P201-P202-P261-P264-P270-P272-P273-P280-P301+P310+P330-P302+P352-P305+P351+P338+P310-P308+P313-P333+P313-P391-P405-P501
Class:6.1
UN#:2811
Packing Group:Ⅲ

Application In Synthesis of 8-Hydroxyquinoline

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 148-24-3 ]
  • Downstream synthetic route of [ 148-24-3 ]

[ 148-24-3 ] Synthesis Path-Upstream   1~16

  • 1
  • [ 148-24-3 ]
  • [ 103987-81-1 ]
References: [1] Dalton Transactions, 2006, # 19, p. 2288 - 2290.
  • 2
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
YieldReaction ConditionsOperation in experiment
71.21% With potassium hydroxide In ethanolReflux General procedure: Cu (II) and Co (II) ions was synthesized by modifyingliterature methods8.1mmole of 8-hydroxyquinolinewas dissolved in alcoholic KOH. This solution wasadded drop wise to the solution of 1mmole metalsalt in alcohol. The reaction mixture was reuxedfor appropriate time. The solid product was obtainedafter completion of the reaction.The ligand 8-Hydroxyquinoline with Ni (II),Cu (II) and Co (II) ions was synthesized by modifyingliterature methods8.1mmole of 8-hydroxyquinolinewas dissolved in alcoholic KOH. This solution wasadded drop wise to the solution of 1mmole metalsalt in alcohol. The reaction mixture was reuxedfor appropriate time. The solid product was obtainedafter completion of the reaction.
References: [1] Journal of Medicinal Chemistry, 2012, vol. 55, # 23, p. 10448 - 10459.
[2] Oriental Journal of Chemistry, 2016, vol. 32, # 6, p. 2999 - 3013.
[3] Chemische Berichte, 1985, vol. 118, # 4, p. 1556 - 1563.
  • 3
  • [ 148-24-3 ]
  • [ 6046-93-1 ]
  • [ 10380-28-6 ]
References: [1] Journal of Solid State Chemistry, 1993, vol. 106, p. 451 - 460.
[2] Canadian Journal of Chemistry, 1983, vol. 61, p. 2154 - 2158.
[3] Research on Chemical Intermediates, 2015, vol. 41, # 8, p. 5703 - 5712.
  • 4
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
References: [1] Journal of the American Chemical Society, 1957, vol. 79, p. 4041.
[2] Gmelin Handbuch, Gmelin Handbook: Cu: MVol.B4, 116, page 1696 - 1699, .
  • 5
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
References: [1] Theoretical and Experimental Chemistry, 1989, vol. 25, p. 97 - 101[2] Teoreticheskaya i Eksperimental'naya Khimiya, 1989, vol. 25, p. 108 - 112.
[3] Industrial and Engineering Chemistry, Analytical Edition, 1943, vol. 15, p. 346 - 349.
[4] Analyst (Cambridge, United Kingdom), 1933, vol. 58, p. 388 - 395.
[5] , 1937, vol. 26, p. 391 - 413.
[6] Gmelin Handbuch, Gmelin Handbook: Cu: MVol.B4, 116, page 1696 - 1699, .
[7] Gmelin Handbuch, Gmelin Handbook: Cu: MVol.B4, 116, page 1696 - 1699, .
  • 6
  • [ 148-24-3 ]
  • [ 142-71-2 ]
  • [ 10380-28-6 ]
References: [1] Kinetics and Catalysis, 1985, vol. 26, p. 50 - 57[2] Kinetika i Kataliz, 1985, vol. 26, p. 61 - 68.
[3] Gazzetta Chimica Italiana, 1923, vol. 53, p. 605 - 616.
[4] Monatshefte fuer Chemie, [5] Monatshefte fuer Chemie, 1882, vol. 3, p. 531 - 569.
[6] Gmelin Handbuch, Gmelin Handbook: Cu: MVol.B4, 116, page 1696 - 1699, .
[7] Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry, 1990, vol. 29, # 5, p. 454 - 457.
  • 7
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
References: [1] Bulletin of the Chemical Society of Japan, 1988, vol. 61, # 5, p. 1761 - 1766.
[2] Zeitschrift fuer Naturforschung, Teil B: Chemical Sciences, [3] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995, vol. 50, p. 524 - 528.
[4] Zeitschrift fuer Naturforschung, Teil B: Chemical Sciences, [5] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995, vol. 50, p. 524 - 528.
  • 8
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
References: [1] Zeitschrift fuer Naturforschung, Teil B: Chemical Sciences, [2] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995, vol. 50, p. 524 - 528.
[3] Spectrochimica Acta, 1956, vol. 8, p. 1 - 8.
[4] Zeitschrift fuer Naturforschung, Teil B: Chemical Sciences, [5] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995, vol. 50, p. 524 - 528.
[6] Gmelin Handbuch, Gmelin Handbook: Cu: MVol.B4, 116, page 1696 - 1699, .
  • 9
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
References: [1] Zeitschrift fuer Naturforschung, Teil B: Chemical Sciences, [2] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995, vol. 50, p. 524 - 528.
[3] Spectrochimica Acta, 1956, vol. 8, p. 1 - 8.
[4] Zeitschrift fuer Naturforschung, Teil B: Chemical Sciences, [5] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995, vol. 50, p. 524 - 528.
[6] Gmelin Handbuch, Gmelin Handbook: Cu: MVol.B4, 116, page 1696 - 1699, .
  • 10
  • [ 148-24-3 ]
  • [ 34946-82-2 ]
  • [ 10380-28-6 ]
References: [1] Dalton Transactions, 2017, vol. 46, # 44, p. 15330 - 15339.
  • 11
  • [ 148-24-3 ]
  • [ 12775-96-1 ]
  • [ 10380-28-6 ]
  • [ 1333-74-0 ]
References: [1] Russian Journal of Physical Chemistry, 1980, vol. 54, # 12, p. 1784 - 1786[2] Zhurnal Fizicheskoi Khimii, 1980, vol. 54, p. 3118 - 3122.
  • 12
  • [ 148-24-3 ]
  • [ 12775-96-1 ]
  • [ 10380-28-6 ]
References: [1] Helvetica Chimica Acta, 1925, vol. 8, p. 596 - 602.
[2] Gmelin Handbuch, Gmelin Handbook: Cu: MVol.B4, 116, page 1696 - 1699, .
  • 13
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
References: [1] Bulletin of the Chemical Society of Japan, 1984, vol. 57, # 6, p. 1675 - 1676.
  • 14
  • [ 148-24-3 ]
  • [ 10380-28-6 ]
References: [1] Thermochimica Acta, 1984, vol. 81, p. 223 - 230.
  • 15
  • [ 148-24-3 ]
  • [ 7758-99-8 ]
  • [ 10380-28-6 ]
References: [1] Investigational New Drugs, 2017, vol. 35, # 6, p. 682 - 690.
  • 16
  • [ 1148-79-4 ]
  • [ 148-24-3 ]
  • [ 6046-93-1 ]
  • [ 10380-28-6 ]
  • [ 443913-66-4 ]
References: [1] Dalton Transactions, 2017, vol. 46, # 44, p. 15330 - 15339.
 

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