成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 136470-78-5 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 136470-78-5
Chemical Structure| 136470-78-5
Structure of 136470-78-5 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 136470-78-5 ]

Related Doc. of [ 136470-78-5 ]

Alternatived Products of [ 136470-78-5 ]
Product Citations

Product Details of [ 136470-78-5 ]

CAS No. :136470-78-5 MDL No. :MFCD00903850
Formula : C14H18N6O Boiling Point : -
Linear Structure Formula :C11H12N5ONC3H6 InChI Key :MCGSCOLBFJQGHM-SCZZXKLOSA-N
M.W : 286.33 Pubchem ID :441300
Synonyms :
Chemical Name :((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol

Safety of [ 136470-78-5 ]

Signal Word:Danger Class:N/A
Precautionary Statements:P501-P261-P202-P285-P201-P280-P272-P308+P313-P304+P341-P302+P352-P333+P313-P363-P405 UN#:N/A
Hazard Statements:H361-H317-H334-H341 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 136470-78-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 136470-78-5 ]

[ 136470-78-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 13211-32-0 ]
  • [ 136470-78-5 ]
  • ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methyl 2-(tert-butoxy)acetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
74% With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 25 - 30℃; To a suspension of Abacavir free base (75 g, 261.9 mmol), 2-(tert-butoxy) acetic acid (41.54 g, 314.3 mmol) and DMAP (48 g, 392.9 mmol) in DCM (825 mL) was added EDC-HC1 (3 *25.11 g, 393 mmol) lot wise and the mixture was stirred for 2-3 hours at 25-30°C. Afterreaction completion, added 10percent ammonium chloride solution, separated the organic layer and concentrated under vacuum. Crude dissolved in toluene and washed with 15percent aqueous acetic acid, followed by water, 5percent aqueous sodium bicarbonate solution and finally 10percent aqueous sodium chloride solution. The organic layer was concentrated under vacuum, dissolved in DCM (150 mL) and slowly added n-heptane (450 mL). The suspension was stirred for 10-12 hours at25-30°C, followed by 5-6 hours at 0-5°C. The product was filtered, washed with n-heptane (150 mL) and dried under vacuum to yield ((iS, 4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9- yl) cyclopent-2-en-1-yl) methyl 2-(tert-butoxy) acetate as a white powder (yield 74percent).The purity by HPLC analysis was 99.3percent. ?H NMR (400 MHz, DMSO-d6): 7.60 (s, 1H), 7.27 (s, 1H), 6.08 (d, J= 5.2 Hz, 1H), 5.96 (d, J= 6.0 Hz, 1H), 5.81 (s, 2H), 5.42?5.41 (m,1H), 4.16-4.13 (m, 2H), 3.99 (d, J= 3.2 Hz, 2H), 3.11-3.08 (m, 1H), 3.11-3.08 (m, 1H), 2.69?2.65 (m, 1H,), 1.62? 1.58 (m, 1H), 1.12 (s, 9H), 0.65 ?0.57 (m, 4H). JR (KBr): v 3327, 3191,2973, 1764, 1648, 1610, 1487, 1265, and 1186 cm1.
Recommend Products
Same Skeleton Products
Historical Records
; ;