Structure of Nevirapine
CAS No.: 129618-40-2
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Nevirapine is an inhibitor of reverse transcriptase which is used in combination with nucleoside analogues to treat HIV-1 infection.
Synonyms: BI-RG 587; HSDB 7164; BIRG 0587
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
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CAS No. : | 129618-40-2 |
Formula : | C15H14N4O |
M.W : | 266.30 |
SMILES Code : | O=C1C2=CC=CN=C2N(C3CC3)C4=NC=CC(C)=C4N1 |
Synonyms : |
BI-RG 587; HSDB 7164; BIRG 0587
|
MDL No. : | MFCD00866928 |
InChI Key : | NQDJXKOVJZTUJA-UHFFFAOYSA-N |
Pubchem ID : | 4463 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
In Vivo:
Species
|
Animal Model
|
Administration | Dosage | Frequency | Description | References |
Oreochromis mossambicus | Oreochromis mossambicus | Water exposure | 1.48 mg/L and 3.74 mg/L | 30 days | The study investigated the effects of nevirapine and its mixture with antibiotics on the gonads of Oreochromis mossambicus. Female fish exposed to 3.74 mg/L nevirapine and its mixture showed significantly higher ovary indices, with increased vitellogenic oocyte atresia and vacuolation of the interstitial tissue observed in the ovaries. | PMC8049986 |
Mice | LDLr ?/? and hA-I transgenic mice | Oral | 20 mg/kg | Once daily for 12 weeks | To study the effects of nevirapine on HDL cholesterol levels and reverse cholesterol transport, results showed that nevirapine significantly increased HDL cholesterol levels at week 4, but no significant difference was observed at weeks 8 and 12 compared to control | PMC2755296 |
Mice | LINE-1a mice | Oral | 100 μg | Once daily for 4 weeks | Nevirapine treatment did not significantly affect the progression of ataxia in LINE-1a mice. | PMC9588660 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00002166 | HIV Infections | PHASE3 | COMPLETED | - | Boehringer Ingelheim Pharmaceu... More >>ticals Inc, Ridgefield, Connecticut, 06877, United States Less << |
NCT00000808 | HIV Infections|Pregnancy | PHASE1 | COMPLETED | 1998-09-01 | UCSD Med Ctr / Pediatrics / Cl... More >>inical Sciences, La Jolla, California, 920930672, United States|Los Angeles County - USC Med Ctr, Los Angeles, California, 90033, United States|UCLA Med Ctr / Pediatric, Los Angeles, California, 900951752, United States|Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles, California, 905022004, United States|San Francisco Gen Hosp, San Francisco, California, 94110, United States|UCSF / Moffitt Hosp - Pediatric, San Francisco, California, 941430105, United States|Univ of Connecticut / Farmington, Farmington, Connecticut, 06032, United States|Connecticut Children's Med Ctr - Pediatric, Hartford, Connecticut, 06106, United States|Chicago Children's Memorial Hosp, Chicago, Illinois, 606143394, United States|Univ of Chicago Children's Hosp, Chicago, Illinois, 606371470, United States|Children's Hosp of Boston, Boston, Massachusetts, 021155724, United States|Boston City Hosp / Pediatrics, Boston, Massachusetts, 02118, United States|Univ of Massachusetts Med School, Worcester, Massachusetts, 016550001, United States|Univ of Medicine & Dentistry of New Jersey / Univ Hosp, Newark, New Jersey, 071032714, United States|Mount Sinai Med Ctr / Pediatrics, New York, New York, 10029, United States|San Juan City Hosp, San Juan, 009367344, Puerto Rico Less << |
NCT01335360 | HIV Infection | COMPLETED | 2025-06-03 | Jeffrey Goodman Clinic, Los An... More >>geles, California, 90028, United States Less << | |
NCT02184091 | Renal Insufficiency|Hepatic In... More >>sufficiency Less << | PHASE1 | COMPLETED | - | - |
NCT00405171 | HIV Infections|Hypercholestero... More >>lemia|Antiretroviral Therapy Less << | PHASE4 | COMPLETED | 2025-02-06 | C?te de Nacre University hospi... More >>tal, Caen, 14033, France Less << |
NCT00199979 | Hiv Infection With Antiretrovi... More >>ral Therapy Indication|CD4 Below 350/μL or Below 15% Less << | PHASE3 | UNKNOWN | 2025-06-08 | Cisih, Clinique Medical A, Hop... More >>itaux Universitaires, Strasbourg, Alsace, 67091, France Less << |
NCT00000747 | HIV Infections | PHASE2 | COMPLETED | - | UCSD, San Diego, California, 9... More >>2103, United States Less << |
NCT00310843 | HIV Infections | COMPLETED | - | 1100.1452.01006 Boehringer Ing... More >>elheim Investigational Site, Birmingham, Alabama, United States|1100.1452.01013 Boehringer Ingelheim Investigational Site, Denver, Colorado, United States|1100.1452.99999 Boehringer Ingelheim Investigational Site, Baltimore, Connecticut, United States|1100.1452.01011 Boehringer Ingelheim Investigational Site, New Haven, Connecticut, United States|1100.1452.01003 Boehringer Ingelheim Investigational Site, Baltimore, Maryland, United States|1100.1452.01002 Boehringer Ingelheim Investigational Site, Boston, Massachusetts, United States|1100.1452.01014 Boehringer Ingelheim Investigational Site, Springfield, Massachusetts, United States|1100.1452.01015 Boehringer Ingelheim Investigational Site, St. Louis, Missouri, United States|1100.1452.01016 Boehringer Ingelheim Investigational Site, New York, New York, United States|1100.1452.01012 Boehringer Ingelheim Investigational Site, Chapel hill, North Carolina, United States|1100.1452.01001 Boehringer Ingelheim Investigational Site, Nashville, Tennessee, United States|1100.1452.01004 Boehringer Ingelheim Investigational Site, Fort Worth, Texas, United States|1100.1452.54001 Fundación Huésped, Capital Federal, Argentina|1100.1452.54002 Funcei, Capital Federal, Argentina|1100.1452.54003 Boehringer Ingelheim Investigational Site, Capital Federal, Argentina|1100.1452.54004 Boehringer Ingelheim Investigational Site, Rosario, Argentina|1100.1452.61004 Boehringer Ingelheim Investigational Site, Darlinghurst, New South Wales, Australia|1100.1452.61005 Boehringer Ingelheim Investigational Site, DarlingHurst, New South Wales, Australia|1100.1452.61006 Boehringer Ingelheim Investigational Site, Darlinghurst, New South Wales, Australia|1100.1452.61003 Boehringer Ingelheim Investigational Site, Miami, Queensland, Australia|1100.1452.61002 Boehringer Ingelheim Investigational Site, Carlton, Victoria, Australia|1100.1452.61008 Boehringer Ingelheim Investigational Site, Melbourne, Victoria, Australia|1100.1452.61001 Boehringer Ingelheim Investigational Site, South Yarra, Victoria, Australia|1100.1452.01501 St. Paul's Hospital, Vancouver, British Columbia, Canada|1100.1452.01504 Boehringer Ingelheim Investigational Site, Vancouver, British Columbia, Canada|1100.1452.01502 Toronto General Hospital, Toronto, Ontario, Canada|1100.1452.3304A H?pital Saint André, Bordeaux, France|1100.1452.3306A H?pital H?tel Dieu, Lyon cedex 2, France|1100.1452.3311A H?pital Edouard Herriot, Lyon Cedex 3, France|1100.1452.3311C H?pital Edouard Herriot, Lyon cedex 3, France|1100.1452.3311D H?pital Edouard Herriot, Lyon cedex 3, France|1100.1452.3306B Hop H?tel Dieu, Lyon, France|1100.1452.3311B Pavillon P, Lyon, France|1100.1452.3305A H?pital h?tel Dieu, Nantes cedex 1, France|1100.1452.3305B H?pital h?tel Dieu, Nantes cedex 1, France|1100.1452.3305C H?pital h?tel Dieu, Nantes cedex 1, France|1100.1452.3305E H?pital h?tel Dieu, Nantes cedex 1, France|1100.1452.3305H H?pital h?tel Dieu, Nantes cedex 1, France|1100.1452.3305D H?pital H?tel Dieu, Nantes, France|1100.1452.3305F H?pital H?tel Dieu, Nantes, France|1100.1452.3305G H?pital H?tel Dieu, Nantes, France|1100.1452.3305I H?pital H?tel Dieu, Nantes, France|1100.1452.3313A H?pital Saint Antoine, Paris cedex 12, France|1100.1452.3302A H?pital Tenon, Paris cedex 20, France|1100.1452.3301A H?pital Saint Louis, Paris, France|1100.1452.3303A H?pital de la Pité Salpêtrière, Paris, France|1100.1452.3310A H?pital Bichat Claude Bernard, Paris, France|1100.1452.3310B H?pital Bichat Claude Bernard, Paris, France|1100.1452.3313B H?pital Saint Antoine, Paris, France|1100.1452.3313C H?pital Saint Antoine, Paris, France|1100.1452.3314A H?pital Européen Georges Pompidou, Paris, France|1100.1452.3308A H?pital Purpan, Toulouse cedex 9, France|1100.1452.3308B H?pital Purpan, Toulouse, France|1100.1452.3307A H?pital Guy Chateliez, Tourcoing cedex, France|1100.1452.3307B H?pital Guy Chateliez, Tourcoing cedex, France|1100.1452.3307C H?pital Guy Chateliez, Tourcoing cedex, France|1100.1452.3307D H?pital Guy Chateliez, Tourcoing cedex, France|1100.1452.3307E H?pital Guy Chateliez, Tourcoing cedex, France|1100.1452.3312A H?pital Brabois, Vandoeuvre les Nancy, France|1100.1452.4901 Boehringer Ingelheim Investigational Site, Berlin, Germany|1100.1452.4902 Boehringer Ingelheim Investigational Site, Berlin, Germany|1100.1452.9907 Boehringer Ingelheim Investigational Site, Berlin, Germany|1100.1452.4903 Boehringer Ingelheim Investigational Site, Bochum, Germany|1100.1452.4918 Boehringer Ingelheim Investigational Site, Bonn, Germany|1100.1452.4912 Boehringer Ingelheim Investigational Site, Düsseldorf, Germany|1100.1452.4904 Boehringer Ingelheim Investigational Site, Essen, Germany|1100.1452.4933 Boehringer Ingelheim Investigational Site, Frankfurt am Main, Germany|1100.1452.4916 Boehringer Ingelheim Investigational Site, Hamburg, Germany|1100.1452.4931 Boehringer Ingelheim Investigational Site, Hamburg, Germany|1100.1452.4910 Boehringer Ingelheim Investigational Site, München, Germany|1100.1452.4900 Universit?tsklinikum Ulm, Ulm, Germany|1100.1452.4932 Boehringer Ingelheim Investigational Site, Würzburg, Germany|1100.1452.31001 Academisch Medisch Centrum, Amsterdam, Netherlands|1100.1452.31002 Onze Lieve Vrouwen Gasthuis, Amsterdam, Netherlands|1100.1452.34005 Boehringer Ingelheim Investigational Site, Badalona, Spain|1100.1452.34001 Boehringer Ingelheim Investigational Site, Barcelona, Spain|1100.1452.34002 Boehringer Ingelheim Investigational Site, Barcelona, Spain|1100.1452.34004 Boehringer Ingelheim Investigational Site, Barcelona, Spain|1100.1452.34003 Boehringer Ingelheim Investigational Site, L'Hospitalet de Llobregat, Spain|1100.1452.34006 Boehringer Ingelheim Investigational Site, Madrid, Spain|1100.1452.34007 Boehringer Ingelheim Investigational Site, Madrid, Spain|1100.1452.34010 Boehringer Ingelheim Investigational Site, Madrid, Spain|1100.1452.34011 Boehringer Ingelheim Investigational Site, Madrid, Spain|1100.1452.34009 Boehringer Ingelheim Investigational Site, Sevilla, Spain|1100.1452.88602 Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan|1100.1452.88603 E-Da Hospital, Kaohsiung, Taiwan|1100.1452.88605 Chung-Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan|1100.1452.88606 China Medical University Hospital, Taichung, Taiwan|1100.1452.88601 National Taiwan University Hospital, Taipei, Taiwan|1100.1452.88604 Taipei City Hospital, Taipei, Taiwan|1100.1452.66001 Boehringer Ingelheim Investigational Site, Bangkok, Thailand|1100.1452.66002 Boehringer Ingelheim Investigational Site, Bangkok, Thailand|1100.1452.66003 Boehringer Ingelheim Investigational Site, Khon Kaen, Thailand|1100.1452.44006 Boehringer Ingelheim Investigational Site, Birmingham, United Kingdom|1100.1452.44004 Boehringer Ingelheim Investigational Site, Brighton, United Kingdom|1100.1452.44001 Boehringer Ingelheim Investigational Site, Coventry, United Kingdom|1100.1452.44002 Boehringer Ingelheim Investigational Site, London, United Kingdom|1100.1452.44005 Boehringer Ingelheim Investigational Site, London, United Kingdom|1100.1452.44008 Boehringer Ingelheim Investigational Site, London, United Kingdom|1100.1452.44009 Boehringer Ingelheim Investigational Site, London, United Kingdom|1100.1452.44003 Boehringer Ingelheim Investigational Site, Manchester, United Kingdom|1100.1452.44007 Boehringer Ingelheim Investigational Site, Plaistow, London, United Kingdom Less << | |
NCT00001135 | HIV Infections|Pregnancy | PHASE3 | COMPLETED | 2025-05-01 | Univ of Alabama at Birmingham ... More >>- Pediatric, Birmingham, Alabama, 35233, United States|UCSD Med Ctr / Pediatrics / Clinical Sciences, La Jolla, California, 920930672, United States|UCLA Med Ctr / Pediatric, Los Angeles, California, 900951752, United States|UCSF / Moffitt Hosp - Pediatric, San Francisco, California, 941430105, United States|Children's Hosp of Washington DC, Washington, District of Columbia, 200102916, United States|Univ of Miami (Pediatric), Miami, Florida, 33161, United States|Chicago Children's Memorial Hosp, Chicago, Illinois, 606143394, United States|Tulane Univ / Charity Hosp of New Orleans, New Orleans, Louisiana, 701122699, United States|Johns Hopkins Hosp - Pediatric, Baltimore, Maryland, 212874933, United States|Children's Hosp of Boston, Boston, Massachusetts, 021155724, United States|Univ of Massachusetts Med School, Worcester, Massachusetts, 016550001, United States|Univ of Medicine & Dentistry of New Jersey / Univ Hosp, Newark, New Jersey, 071032714, United States|Bellevue Hosp / New York Univ Med Ctr, New York, New York, 10016, United States|Columbia Presbyterian Med Ctr, New York, New York, 10032, United States|Duke Univ Med Ctr, Durham, North Carolina, 277103499, United States|Children's Hosp of Philadelphia, Philadelphia, Pennsylvania, 191044318, United States|Saint Jude Children's Research Hosp of Memphis, Memphis, Tennessee, 381052794, United States|Texas Children's Hosp / Baylor Univ, Houston, Texas, 77030, United States|Children's Hospital & Medical Center / Seattle ACTU, Seattle, Washington, 981050371, United States|Univ of Puerto Rico / Univ Children's Hosp AIDS, San Juan, 009365067, Puerto Rico Less << |
NCT00006279 | HIV Infections | PHASE1 | COMPLETED | 2025-05-05 | Kathy George, Durham, North Ca... More >>rolina, 27713, United States Less << |
NCT00000942 | HIV Infections|Pregnancy | PHASE3 | COMPLETED | 2025-05-01 | Princess Margaret Hosp, Nassau... More >>, Bahamas|Hopital Hotel Dieu de Lyon, Lyon, France|CHRU de Nantes, Nantes, France|Universita Frederico II, Napoli, Italy|Hosp Doce De Octubre, Madrid, Spain Less << |
NCT00000869 | HIV Infections|Pregnancy | PHASE3 | COMPLETED | 2025-05-01 | Univ of Alabama at Birmingham ... More >>- Pediatric, Birmingham, Alabama, 35233, United States|Univ of South Alabama, Mobile, Alabama, 36604, United States|UCSD Med Ctr / Pediatrics / Clinical Sciences, La Jolla, California, 920930672, United States|Long Beach Memorial (Pediatric), Long Beach, California, 90801, United States|Los Angeles County - USC Med Ctr, Los Angeles, California, 90033, United States|UCLA Med Ctr / Pediatric, Los Angeles, California, 900951752, United States|Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles, California, 905022004, United States|San Francisco Gen Hosp, San Francisco, California, 94110, United States|UCSF / Moffitt Hosp - Pediatric, San Francisco, California, 941430105, United States|Children's Hosp of Denver, Denver, Colorado, 802181088, United States|Connecticut Children's Med Ctr, Farmington, Connecticut, 060303805, United States|Univ of Connecticut / Farmington, Farmington, Connecticut, 06032, United States|Washington Hosp Ctr, Washington, District of Columbia, 200102931, United States|Howard Univ Hosp, Washington, District of Columbia, 20060, United States|North Broward Hosp District, Fort Lauderdale, Florida, 33311, United States|Univ of Florida Gainesville, Gainesville, Florida, 32610, United States|Univ of Florida Health Science Ctr / Pediatrics, Jacksonville, Florida, 32209, United States|Univ of Miami / Jackson Memorial Hosp, Miami, Florida, 33136, United States|Univ of Miami (Pediatric), Miami, Florida, 33161, United States|Med College of Georgia, Augusta, Georgia, 30912, United States|The Med Ctr Inc, Columbus, Georgia, 31901, United States|Cook County Hosp, Chicago, Illinois, 60612, United States|Univ of Illinois College of Medicine / Pediatrics, Chicago, Illinois, 60612, United States|Chicago Children's Memorial Hosp, Chicago, Illinois, 606143394, United States|Univ of Chicago Children's Hosp, Chicago, Illinois, 606371470, United States|Tulane Univ / Charity Hosp of New Orleans, New Orleans, Louisiana, 701122699, United States|Tulane Univ Hosp of New Orleans, New Orleans, Louisiana, 701122699, United States|Univ Hosp, New Orleans, Louisiana, 70112, United States|Univ of Maryland at Baltimore / Univ Med Ctr, Baltimore, Maryland, 21201, United States|Johns Hopkins Hosp - Pediatric, Baltimore, Maryland, 212874933, United States|Children's Hosp of Boston, Boston, Massachusetts, 021155724, United States|Brigham and Women's Hosp, Boston, Massachusetts, 02115, United States|Boston City Hosp / Pediatrics, Boston, Massachusetts, 02118, United States|Baystate Med Ctr of Springfield, Springfield, Massachusetts, 01199, United States|Univ of Massachusetts Med School, Worcester, Massachusetts, 016550001, United States|Children's Hosp of Michigan, Detroit, Michigan, 48201, United States|Univ of Mississippi Med Ctr, Jackson, Mississippi, 39213, United States|Cooper Hosp - Univ Med Ctr / UMDNJ - New Jersey Med Schl, Camden, New Jersey, 08103, United States|UMDNJ - Robert Wood Johnson Med School / Pediatrics, New Brunswick, New Jersey, 089030019, United States|St Peter's Med Ctr, New Brunswick, New Jersey, 08903, United States|Univ of Medicine & Dentistry of New Jersey / Univ Hosp, Newark, New Jersey, 071032714, United States|Saint Joseph's Hosp and Med Ctr/UMDNJ - New Jersey Med Schl, Newark, New Jersey, 07103, United States|Children's Hosp at Albany Med Ctr, Albany, New York, 12208, United States|Bronx Lebanon Hosp Ctr, Bronx, New York, 10457, United States|Bronx Municipal Hosp Ctr/Jacobi Med Ctr, Bronx, New York, 10461, United States|North Shore Univ Hosp, Great Neck, New York, 11021, United States|Bellevue Hosp / New York Univ Med Ctr, New York, New York, 10016, United States|Metropolitan Hosp Ctr, New York, New York, 10029, United States|Columbia Presbyterian Med Ctr, New York, New York, 10032, United States|Univ of Rochester Med Ctr, Rochester, New York, 146420001, United States|SUNY Health Sciences Ctr at Syracuse / Pediatrics, Syracuse, New York, 13210, United States|Duke Univ Med Ctr, Durham, North Carolina, 277103499, United States|Univ of North Carolina at Chapel Hill / Duke Univ Med Ctr, Durham, North Carolina, 27710, United States|Children's Hosp of Philadelphia, Philadelphia, Pennsylvania, 191044318, United States|Hosp of the Univ of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States|Saint Christopher's Hosp for Children, Philadelphia, Pennsylvania, 191341095, United States|Temple Univ School of Medicine, Philadelphia, Pennsylvania, 191341095, United States|Med Univ of South Carolina, Charleston, South Carolina, 294253312, United States|Regional Med Ctr at Memphis, Memphis, Tennessee, 38103, United States|Methodist Hosp Central, Memphis, Tennessee, 381052794, United States|Saint Jude Children's Research Hosp of Memphis, Memphis, Tennessee, 381052794, United States|Vanderbilt Univ Med Ctr, Nashville, Tennessee, 372322581, United States|Children's Med Ctr of Dallas, Dallas, Texas, 75235, United States|Texas Children's Hosp / Baylor Univ, Houston, Texas, 77030, United States|Children's Hosp of the King's Daughters, Norfolk, Virginia, 23507, United States|Senetara Norfolk Gen Hosp, Norfolk, Virginia, 23507, United States|Med College of Virginia, Richmond, Virginia, 23219, United States|Children's Hospital & Medical Center / Seattle ACTU, Seattle, Washington, 981050371, United States|Tacoma Gen Hosp, Tacoma, Washington, 98405, United States|Ramon Ruiz Arnau Univ Hosp / Pediatrics, Bayamon, 00956, Puerto Rico|Univ of Puerto Rico / Univ Children's Hosp AIDS, San Juan, 009365067, Puerto Rico|San Juan City Hosp, San Juan, 009367344, Puerto Rico Less << |
NCT00000634 | HIV Infections | COMPLETED | - | Univ of Massachusetts Med Ctr ... More >>/ Biotech II, Worcester, Massachusetts, 01605, United States Less << | |
NCT00415090 | HIV Infections | PHASE4 | COMPLETED | 2025-07-06 | Hospital.Universitari Germans ... More >>Trias i Pujol, Badalona, Barcelona, 08916, Spain|Hospital General de Granollers, Granollers, Barcelona, 08400, Spain|Centre Penitenciari Quatre Camins, Granollers, Barcelona, 08430, Spain|Hospital de Bellvitge, Hospitalet de Llobregat, Barcelona, 08907, Spain|Mutua de Terrassa, Terrassa, Barcelona, 08221, Spain|Hospital La Candelaria, Tenerife, Canarias, 38010, Spain|Hospital Universitari Sant Joan de Reus, Reus, Tarragona, 43201, Spain|Centre Penitenciari Brians, Barcelona, 08009, Spain|Hopsital de Sant Pau, Barcelona, 08025, Spain|Hospital Vall d'Hebron, Barcelona, 08035, Spain|Hospital Clínic i Provincial de Barcelona, Barcelona, 08036, Spain|Hospital Sant Jaume de Calella, Barcelona, 08370, Spain|Centre Penitenciari Homes, Barcelona, Spain|Hospital Clínico San Carlos de Madrid, Madrid, 28040, Spain|Hospital de Tortosa, Tortosa, 43500, Spain|Hospital La Fe de Valencia, Valencia, 46009, Spain|Hospital Miguel Servet, Zaragoza, 50009, Spain Less << |
NCT00274001 | HIV Infections|Quality of Life | PHASE4 | COMPLETED | 2025-03-04 | Ospedale Regionale, Ancona, 60... More >>020, Italy|Ospedale Santa Maria Annunziata, Antella (fi), 50011, Italy|Clinica di Malattie Infettive, Bari, 70124, Italy|Ospedali Riuniti di Bergamo, Bergamo, 24128, Italy|Ospedale degli Infermi di Biella, Biella, 13900, Italy|Istituto di Malattie Infettive, Bologna, 40138, Italy|Ospedale Civile, Brescia, 25123, Italy|Spedali Civili di Brescia, Brescia, 25123, Italy|Ospedale di Circolo di Busto, Busto Arsizio (va), 21052, Italy|Ospedale SS. Trinità, Cagliari, 09100, Italy|Azienda Ospedaliera Arcispedale S. Anna, Ferrara, 44100, Italy|Ospedale San Martino, Genova, 16132, Italy|Presidio Ospedaliero "A. Manzoni", Lecco, 23900, Italy|Azienda Ospedaliera Carlo Poma, Mantova, 46100, Italy|Ospedale Luigi Sacco, Milano, 20100, Italy|Fondazione Centro S. Raffaele del Monte Tabor, Milano, 20127, Italy|Azienda Ospedaliera "Luigi Sacco", Milano, 20157, Italy|Ospedale Luigi Sacco, Milano, 20157, Italy|Policlinico Universitario, Modena, 41100, Italy|Ospedale A. Cotugno, Napoli, 80131, Italy|Azienda Ospedaliera di Padova, Padova, 35128, Italy|IRCCS Policlinico San Matteo, Pavia, 27100, Italy|Ospedale Civile, Piacenza, 29100, Italy|Ospedale Cisanello, Pisa, 35128, Italy Less << |
NCT00000962 | HIV Infections | PHASE1 | COMPLETED | - | Univ of California / San Diego... More >> Treatment Ctr, San Diego, California, 921036325, United States|Univ of Massachusetts Med Ctr, Worcester, Massachusetts, 01655, United States|Univ of Minnesota, Minneapolis, Minnesota, 55455, United States Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.76mL 0.75mL 0.38mL |
18.78mL 3.76mL 1.88mL |
37.55mL 7.51mL 3.76mL |
Tags: Nevirapine | BI-RG 587 | NSC 641530 | NVP | NSC641530 | NSC 641530 | NSC-641530 | HIV | Reverse Transcriptase | Parasite | Human immunodeficiency virus | 129618-40-2
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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