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Chemical Structure| 128517-07-7 Chemical Structure| 128517-07-7
Chemical Structure| 128517-07-7

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CAS No.: 128517-07-7

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Romidepsin (FK 228) is a histone deacetylase (HDAC) inhibitor with anti-tumor activities, inhibiting HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM, and 1.4 μM, respectively. It is produced by Chromobacterium violaceum, inducing cell G2/M phase arrest and apoptosis.

Synonyms: FR 901228; FK 228; NSC 630176

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Product Details of Romidepsin

CAS No. :128517-07-7
Formula : C24H36N4O6S2
M.W : 540.70
SMILES Code : C/C=C(NC([C@@H](CSSCC/C=C/[C@@H](O1)CC2=O)NC([C@@H](C(C)C)N2)=O)=O)/C(N[C@@H](C(C)C)C1=O)=O
Synonyms :
FR 901228; FK 228; NSC 630176
MDL No. :MFCD18433404

Safety of Romidepsin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Romidepsin

epigenetics

Isoform Comparison

Biological Activity

Target

  • HDAC2

    HDAC2, IC50:47 nM

  • HDAC1

    HDAC1, IC50:36 nM

In Vitro:

Cell Line
Concentration Treated Time Description Reference
BR MM cells 100 nM 24 h Evaluate the sensitivity of Romidepsin combined with BTZ in BR MM cells, results showed that the combination significantly increased the apoptosis rate PMC9998874
CD4 T cells 0.15nM-640nM 4 h To measure the ability of Romidepsin to induce histone H4 acetylation in different CD4 T cell subsets, results showed that Romidepsin exhibited higher potency in T EM cells. PMC6943937
HEK293T/17 cells 10 nM 72 h Romidepsin increased the base editing efficiency mediated by ABE7.10, particularly at the A5 position of the CCR5 target site, where the A:T to G:C substitution frequency increased from 10.7% to 37.9%. PMC7913676
HAP1-ABEdox:GFP reporter cells 10 nM 48 h Romidepsin significantly increased GFP expression levels, and at the A6 position of the EGFP target site, the A:T to G:C substitution frequency increased from 37.9% to 72.9%. PMC7913676
RT112 2.5 nM, 5 nM 24 h To evaluate the cytotoxicity and radiosensitizing effects of Romidepsin, results showed that Romidepsin was effective in the nanomolar range and significantly enhanced the sensitivity of bladder cancer cells to ionizing radiation. PMC7181176
MBT2 0.6 nM, 2 nM 24 h To evaluate the cytotoxicity and radiosensitizing effects of Romidepsin, results showed that Romidepsin was effective in the nanomolar range and significantly enhanced the sensitivity of bladder cancer cells to ionizing radiation. PMC7181176
HT1376 0.4 nM, 0.6 nM 24 h To evaluate the cytotoxicity and radiosensitizing effects of Romidepsin, results showed that Romidepsin was effective in the nanomolar range and significantly enhanced the sensitivity of bladder cancer cells to ionizing radiation. PMC7181176
HCT116 colon cancer cells 50 nM 24 h To evaluate the effect of Romidepsin on type I IFN signaling in HCT116 cells PMC7271653
PBMC from healthy donors 50 ng/ml 24 h Romidepsin significantly suppressed the cytotoxicity of NK cells from healthy donors (untreated median=22.65%, romidepsin median= 13.4%; P=.0069). However, cytokine stimulation with IL-12 and IFN- γ significantly increased the cytolytic activity of these healthy NK cells even in romidepsin treated cells (unstimulated median= 13.4%, IL-12 & IFN-α stimulated median= 20.7%; P=.0051). PMC3638752
PBMC from healthy donors 50 ng/ml 48 h Romidepsin treatment significantly decreased CD80 expression in these stimulated cells (non-romidepsin treated median= 72.2%, romidepsin treated median= 33.45%; P= .0277). PMC3638752
PBMC from healthy donors 50 ng/ml 48 h Romidepsin treatment significantly decreased the in vitro production of IL-12 (untreated median= 676, romidepsin treated median= 31; P= .0077). PMC3638752

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description Reference
NSG mice WiT49-PRC-1 tumor model Intraperitoneal injection 4 mg/kg Daily, for 16 days Romidepsin strongly inhibited the growth of WiT49-PRC-1 tumors and effectively blocked their metastasis to the liver and lung. PMC11513831
mice NSG xenograft model intraperitoneal injection 1 mg/kg every 2 days, continuous treatment Evaluate the anti-tumor effect of Romidepsin combined with BTZ in BR MM cell xenograft model, results showed that the combination significantly suppressed tumor growth and improved the survival rate of mice PMC9998874
mice SU-DHL-10 xenograft model intraperitoneal injection 2 mg/kg administered on days 1, 8, 15 To evaluate the in vivo efficacy of Romidepsin in combination with GSK126, results showed significant tumor growth delay and improved overall survival PMC6726529
mice CD1-nude mice intraperitoneal injection 4 mg/kg single injection To evaluate the radiosensitizing effects of Romidepsin in vivo, results showed that Romidepsin combined with ionizing radiation significantly delayed tumor growth without increasing acute or late intestinal and bladder toxicity. PMC7181176

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02661178 Healthy Volunteers Phase 1 Completed - United Kingdom ... More >> Hammersmith Medicines Research London, United Kingdom, NW10 7EW Less <<
NCT01663571 - Terminated(Study is permanentl... More >>y closed to enrollment .Collection of private identifiable information is complete Analysis of private identifiable information is complete) Less << - United States, New York ... More >> NYU Langone Medical Center New York, New York, United States, 10016 Less <<
NCT03432741 Breast Adenocarcinoma ... More >> Recurrent Breast Carcinoma Recurrent Hodgkin Lymphoma Recurrent Mycosis Fungoides Recurrent Non-Hodgkin Lymphoma Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Refractory Hodgkin Lymphoma Refractory Mycosis Fungoides Refractory Nodal Marginal Zone Lymphoma Refractory Non-Hodgkin Lymphoma Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Stage IV Breast Cancer AJCC v6 and v7 Less << Phase 1 Recruiting May 1, 2019 United States, Minnesota ... More >> Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Clinical Trials Referral Office ?? 855-776-0015 ?? ?? Principal Investigator: Grzegorz S. Nowakowski Less <<
NCT03593018 Relapsed Angioimmunoblastic T-... More >>Cell Lymphoma Refractory Angioimmunoblastic T-cell Lymphoma Less << Phase 3 Recruiting December 2021 Belgium ... More >> A. Z. Sint-Jan Brugge-Oostende AV Recruiting Bruges, Belgium Contact: Sylvia SNAUWAERT, MD ?? ?? ?? Cliniques Universitaires de Bruxelles - H?pital Erasme Recruiting Bruxelles, Belgium Contact: Alice WOLFROMM, MD ?? ?? ?? Université Catholique de Louvain Saint-Luc Recruiting Bruxelles, Belgium Contact: Nicole STRAETMANS, MD ?? ?? ?? CHU de Liège Recruiting Liège, Belgium Contact: Christophe BONNET, MD ?? ?? ?? CHU UCL Namur - Site Godinne Recruiting Yvoir, Belgium Contact: Marc ANDRE, MD ?? ?? ?? France Institut d'Hématologie de Basse Normandie Recruiting Caen, France Contact: Gandhi DAMAJ, MD ?? ?? ?? CHU de Clermont-Ferrand - H?pital Estaing Recruiting Clermont-Ferrand, France Contact: Olivier TOURNILHAC, MD ?? ?? ?? CHU Henri Mondor Recruiting Créteil, France Contact: Jehan DUPUIS, MD ?? ?? ?? CHU de Dijon Recruiting Dijon, France Contact: Olivier CASASNOVAS, MD ?? ?? ?? CHU de Grenoble Recruiting Grenoble, France Contact: Rémy GRESSIN, MD ?? ?? ?? CHRU de Lille Recruiting Lille, France Contact: Franck MORSCHHAUSER, MD ?? ?? ?? CHU de Limoges Recruiting Limoges, France Contact: Céline KENNEL, MD ?? ?? ?? CHU de Montpellier - H?pital Saint-Eloi Recruiting Montpellier, France Contact: Guillaume CARTRON, MD ?? ?? ?? CHU de Nantes - H?tel Dieu Recruiting Nantes, France Contact: Steven LE GOUILL, MD ?? ?? ?? H?pital Necker Recruiting Paris, France Contact: Richard DELARUE, MD ?? ?? ?? H?pital Saint-Louis Recruiting Paris, France Contact: Catherine THIEBLEMONT, MD ?? ?? ?? CHU Haut-Lévèque - Centre Fran?ois Magendie Recruiting Pessac, France Contact: Kamal BOUABDALLAH, MD ?? ?? ?? CHU Lyon-Sud Recruiting Pierre-Bénite, France Contact: Emmanuel BACHY, MD ?? ?? ?? CH Annecy Genevois Recruiting Pringy, France Contact: Nicolas DAGUINDAU, MD ?? ?? ?? CHU Pontchaillou Recruiting Rennes, France Contact: Roch HOUOT, MD ?? ?? ?? Centre Henri Becquerel Recruiting Rouen, France Contact: Hervé TILLY, MD ?? ?? ?? IUCT - Oncopole Recruiting Toulouse, France Contact: Lo?c YSEBAERT, MD ?? ?? ?? CHRU de Nancy - H?pital de Brabois Recruiting Vand?uvre-lès-Nancy, France Contact: Lauriane CLEMENT-FILLIATRE, MD Less <<
NCT03703375 Lymphoma, T-Cell Phase 3 Not yet recruiting December 31, 2021 Japan ... More >> National Hospital Organization Nagoya Medical Center Not yet recruiting Nagoya, Aichi, Japan National Cancer Center Hospital East Not yet recruiting Kashiwa, Chiba, Japan Kyushu University Hospital Not yet recruiting Higashi-ku, Fukuoka, Japan University of Tsukuba Hospital Not yet recruiting Tsukuba, Ibataki, Japan Tokai University Hospital Not yet recruiting Isehara, Kanagawa, Japan National University Corporation Tohoku University Hospital Not yet recruiting Sendai, Miyagi, Japan Kindai University Hospital Not yet recruiting Osaka-Sayama, Osaka, Japan Saitama Medical University International Medical Center Not yet recruiting Hidaka, Saitama, Japan National Cancer Center Hospital Not yet recruiting Chuo-ku, Tokyo, Japan The Cancer Institute Hospital of Japanese Foundation For Cancer Research Not yet recruiting Koto-ku, Tokyo, Japan Less <<
NCT02551718 Acute Leukemia of Ambiguous Li... More >>neage Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Recurrent Childhood Acute Lymphoblastic Leukemia Recurrent Childhood Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia Refractory Adult Acute Lymphoblastic Leukemia Refractory Childhood Acute Lymphoblastic Leukemia Less << Not Applicable Recruiting - United States, Washington ... More >> Fred Hutch/University of Washington Cancer Consortium Recruiting Seattle, Washington, United States, 98109 Contact: Pamela S. Becker ?? 206-616-1589 ?? pbecker@u.washington.edu ?? Principal Investigator: Pamela S. Becker Less <<
NCT02788201 Urothelial Carcinoma ... More >> Bladder Cancer Urinary Bladder Neoplasms Less << Phase 2 Recruiting July 1, 2020 United States, Maryland ... More >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office ?? 888-624-1937 Less <<
NCT00037817 Advanced Esophageal Cancers ... More >> Primary Small Cell Lung Cancers Non-Small-Cell Lung Carcinoma Pleural Mesotheliomas Cancers of Non-thoracic Origin With Metastases to the Lungs or Pleura Less << Phase 1 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT01482962 - Completed - -
NCT01482962 Relapsed Peripheral T-Cell Lym... More >>phoma Refractory Peripheral T-Cell Lymphoma Less << Phase 3 Completed - -
NCT00094978 Carcinoma, Small Cell ... More >> Carcinoma, Non-Small-Cell Lung Esophageal Neoplasms Mesothelioma Less << Phase 1 Terminated - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT00299351 Peripheral T Cell Lymphoma (PT... More >>CL) Less << Phase 2 Unknown - -
NCT02512172 Colorectal Cancer Phase 1 Recruiting January 2019 United States, Maryland ... More >> Johns Hopkins Recruiting Baltimore, Maryland, United States, 21205 Principal Investigator: Nilofer Azad, MD Less <<
NCT03619278 HIV Infections Phase 1 Phase 2 Not yet recruiting July 15, 2020 -
NCT00020202 Extensive Stage Small Cell Lun... More >>g Cancer Stage IIIA Non-small Cell Lung Cancer Stage IV Non-small Cell Lung Cancer Recurrent Small Cell Lung Cancer Stage IIIB Non-small Cell Lung Cancer Recurrent Non-small Cell Lung Cancer Less << Phase 2 Completed - United States, Maryland ... More >> Surgery Branch Bethesda, Maryland, United States, 20892 Less <<
NCT00079443 Recurrent Grade 1 Follicular L... More >>ymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Small Lymphocytic Lymphoma Less << Phase 2 Terminated - United States, Maryland ... More >> University of Maryland Greenebaum Cancer Center Baltimore, Maryland, United States, 21201-1595 Less <<
NCT02223208 Peripheral T-cell Lymphomas (P... More >>TCL) PTCL-NOS Angioimmunoblastic T-cell Lymphoma (AITL) ALK- Anaplastic Large Cell Lymphoma (ALCL) Less << Phase 1 Phase 2 Recruiting March 2025 Italy ... More >> Ospedale SS. Antonio e Biagio e Cesare Arrigo Recruiting Alessandria, AL, Italy, 15121 Contact: Manuela Zanni, MD ?? 0039 0131206133 ?? manuela.zanni@ospedale.al.it ?? Principal Investigator: Flavia Salvi, MD ?? ?? ?? Ospedali Riuniti Umberto I Not yet recruiting Ancona, AN, Italy, 60126 Contact: Attilio Olivieri, PROF ?? 0039 0715964226 ?? a.olivieri@unipm.it ?? Principal Investigator: Attilio Olivieri, PROF ?? ?? ?? AOU Policlinico di Bari Not yet recruiting Bari, BA, Italy, 70124 Contact: Giorgina Specchia, PROF ?? 0039 0805593471 ?? giorgina.specchia@uniba.it ?? Principal Investigator: Giorgina Specchia, PROF ?? ?? ?? Policlinico S. Orsola Malpighi Recruiting Bologna, BO, Italy, 40138 Contact: Vittorio Stefoni, MD ?? 0039 0516364042 ?? vittorio.stefoni2@unibo.it ?? Principal Investigator: Vittorio Stefoni, MD ?? ?? ?? Spedali Civili Recruiting Brescia, BS, Italy, 26123 Contact: Alessandro Re, MD ?? 0039 0303995438 ?? ematologia@spedalicivili.it ?? Principal Investigator: Alessandro Re, MD ?? ?? ?? Ospedale Businco Recruiting Cagliari, CA, Italy, 09121 Contact: Giuseppina Cabras, MD ?? 0039 0706095171 ?? cabras.giuseppina@tiscali.it ?? Principal Investigator: Giuseppina Cabras, MD ?? ?? ?? Fondazione di Ricerca e Cura "Giovanni Paolo II" Not yet recruiting Campobasso, CB, Italy, 86100 Contact: Sergio Storti, MD ?? 0039 0874312317 ?? sstorti@rm.unicatt.it ?? Principal Investigator: Sergio Storti, MD ?? ?? ?? Azienda Ospedaliera S.Croce e Carle Recruiting Cuneo, CN, Italy, 12100 Contact: Claudia Castellino, MD ?? 0039 0171641070 ?? castellino.c@ospedale.cuneo.it ?? Principal Investigator: Claudia Castellino, MD ?? ?? ?? Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) - Sede di Meldola Not yet recruiting Meldola, FC, Italy, 47014 Contact: Gerardo Musuraca, MD ?? 0039 0543739280 ?? g.musuraca@irst.em.it ?? Principal Investigator: Gerardo Musuraca, MD ?? ?? ?? IRCCS Casa Sollievo Della Sofferenza Not yet recruiting San Giovanni Rotondo, FG, Italy, 71013 Contact: Nicola Cascavilla, MD ?? 0039 0882410566 ?? ematologia@operapadrepio.it ?? Principal Investigator: Nicola Cascavilla, MD ?? ?? ?? IRCCS AOU San Martino - Clinica Ematologica Not yet recruiting Genova, GE, Italy, 16321 Contact: Filippo Ballerini, PROF ?? 0039 0105554336 ?? ballerini@unige.it ?? Principal Investigator: Filippo Ballerini, PROF ?? ?? ?? IRCCS AOU San Martino - UO Ematologia 1 Recruiting Genova, GE, Italy, 16321 Contact: Angela Giovanna Congiu, MD ?? 0039 0105513731 ?? angelagiovanna.congiu@hsanmartino.it ?? Principal Investigator: Angela Giovanna Congiu, MD ?? ?? ?? Istituto Clinico Humanitas Terminated Rozzano, Milano, Italy, 20089 Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Recruiting Milano, MI, Italy, 20122 Contact: Luca Baldini, MD ?? 0039 02 55033334 ?? luca.baldini@unimi.it ?? Principal Investigator: Luca Baldini, PROF ?? ?? ?? Fondazione IRCCS "Istituto Nazionale dei Tumori" Recruiting Milano, MI, Italy, 20133 Contact: Paolo Corradini, PROF ?? 0039 0223902950 ?? paolo.corradini@unimi.it ?? Principal Investigator: Paolo Corradini, PROF ?? ?? ?? Azienda Ospedaliera Ospedale Niguarda Ca' Granda Recruiting Milano, MI, Italy, 20162 Contact: Chiara Rusconi, MD ?? 0039 02 64447597 ?? chiara.rusconi@ospedaleniguarda.it ?? Principal Investigator: Chiara Rusconi, MD ?? ?? ?? AO Ospedali Riuniti Villa Sofia - Cervello (Presidio Cervello) Not yet recruiting Palermo, PA, Italy, 90146 Contact: Caterina Patti, MD ?? 0039 0917803162 ?? kpatti@ospedaliriunitipalermo.it ?? Principal Investigator: Caterina Patti, MD ?? ?? ?? P.O. di Pescara-Ospedale Civile Spirito Santo Not yet recruiting Pescara, PE, Italy, 65126 Contact: Francesco Angrilli, MD ?? 0039 0854252838 ?? f.angrilli@virgilio.it ?? Principal Investigator: Francesco Angrilli, MD ?? ?? ?? IRCCS Centro di Riferimento Oncologico (CRO) Not yet recruiting Aviano, PN, Italy, 33081 Contact: Michele Spina, MD ?? 0039 043459730 ?? mspina@cro.it ?? Principal Investigator: Michele Spina, MD ?? ?? ?? AOU di Parma Not yet recruiting Parma, PR, Italy, 43100 Contact: Francesca Re, MD ?? 0039 0521 703962 ?? fre@ao.pr.it ?? Principal Investigator: Francesca Re, MD ?? ?? ?? Fondazione IRCCS - Policlinico San Matteo Recruiting Pavia, PV, Italy, 27100 Contact: Luca Arcaini, MD ?? 0039 0382501381 ?? luca.arcaini@unipv.it ?? Principal Investigator: Luca Arcaini, MD ?? ?? ?? IRCCS Centro di Riferimento Oncologico della Basilicata (CROB) Not yet recruiting Rionero in Vulture, PZ, Italy, 85028 Contact: Roberto Guariglia, MD ?? 0039 0972726225 ?? robertoguariglia@libero.it ?? Principal Investigator: Roberto Guariglia, MD ?? ?? ?? A.O. Bianchi - Melacrino - Morelli Not yet recruiting Reggio Calabria, RC, Italy, 89125 Contact: Caterina Stelitano, MD ?? 0039 0965397653 ?? cstelit@libero.it ?? Principal Investigator: Caterina Stelitano, MD ?? ?? ?? IRCCS Arcispedale "Santa Maria Nuova" Not yet recruiting Reggio Emilia, RE, Italy, 42123 Contact: Francesco Merli, MD ?? 0039 0522296618 ?? merli.francesco@asmn.re.it ?? Principal Investigator: Francesco Merli, MD ?? ?? ?? Università di Roma "La Sapienza" Active, not recruiting Roma, RM, Italy, 00161 Università Cattolica del Sacro Cuore - Policlinico "A. Gemelli" Not yet recruiting Roma, RM, Italy, 00168 Contact: Stefan Hohaus, MD ?? 0039 0630154278 ?? stephan.hohaus@rm.unicatt.it ?? Principal Investigator: Stefan Hohaus, MD ?? ?? ?? Ospedale degli Infermi Not yet recruiting Rimini, RN, Italy, 47900 Contact: Annalia Molinari, MD ?? 0039 0541705423 ?? annalia.molinari@auslrn.net ?? Principal Investigator: Annalia Molinari, MD ?? ?? ?? AO Città della Salute e della Scienza - Ematologia 1U Not yet recruiting Torino, TO, Italy, 10126 Contact: Federica Cavallo, MD ?? 0039 0116334198 ?? f.cavallo@unito.it ?? Principal Investigator: Federica Cavallo, MD ?? ?? ?? AO Città della Salute e della Scienza - SC Ematologia Recruiting Torino, TO, Italy, 10126 Contact: Annalisa Chiappella, MD ?? 0039 0116336751 ?? achiappella@cittadellasalute.to.it ?? Principal Investigator: Annalisa Chiappella, MD ?? ?? ?? AOU "Santa Maria della Misericordia" Recruiting Udine, UD, Italy, 33100 Contact: Francesco Zaja, MD ?? 0039 0432559604 ?? zaja.francesco@aoud.sanita.fgv.it ?? Principal Investigator: Francesco Zaja, MD ?? ?? ?? Ospedale Borgo Roma Not yet recruiting Verona, VR, Italy, 37134 Contact: Fabio Benedetti, MD ?? 0039 045 8124647 ?? fabio.benedetti@univr.it ?? Principal Investigator: Fabio Benedetti, MD ?? ?? ?? Azienda Ospedaliero-Universitaria Careggi Not yet recruiting Firenze, Italy, 50134 Contact: Luigi Rigacci, MD ?? 0039 055 7946448 ?? luigi.rigacci@unifi.it ?? Principal Investigator: Luigi Rigacci, MD ?? ?? ?? Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale Recruiting Napoli, Italy, 80131 Contact: Antonio Pinto, MD ?? 0039 0815903381 ?? a.pinto@istitutotumori.na.it ?? Principal Investigator: Antonio Pinto, MD ?? ?? ?? Università del Piemonte Orientale - SCDU Ematologia Recruiting Novara, Italy, 28100 Contact: Gianluca Gaidano, PROF ?? 0039 03213732194 ?? gaidano@med.unipmn.it ?? Principal Investigator: Gianluca Gaidano, MD ?? ?? ?? A.O. di Perugia - Santa Maria della Misericordia Not yet recruiting Perugia, Italy, 06132 Contact: Leonardo Flenghi, MD ?? 0039 075 5784110 ?? flenghi@yahoo.it ?? Principal Investigator: Leonardo Flenghi, MD ?? ?? ?? Ospedale G. Da Saliceto - AUSL di Piacenza Not yet recruiting Piacenza, Italy, 29121 Contact: Annalisa Arcari, MD ?? 0039 0523 303719 ?? a.arcari@ausl.pc.it ?? Principal Investigator: Annalisa Arcari, MD ?? ?? ?? UO Ematologia Ospedale S.Maria delle Croci Recruiting Ravenna, Italy, 48121 Contact: Monica Tani, MD ?? 0039 0544286223 ?? monica.tani@auslromagna.it ?? Principal Investigator: Monica Tani, MD Less <<
NCT00042822 Leukemia Lymp... More >>homa Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Less << Phase 2 Completed - United States, New York ... More >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Less <<
NCT00024180 Leukemia Lymp... More >>homa Less << Phase 1 Completed - United States, Ohio ... More >> Arthur G. James Cancer Hospital - Ohio State University Columbus, Ohio, United States, 43210-1240 Less <<
NCT00114257 Chronic Myeloproliferative Dis... More >>orders Leukemia Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Less << Phase 1 Completed - United States, Texas ... More >> M.D. Anderson Cancer Center at University of Texas Houston, Texas, United States, 77030-4009 Less <<
NCT00077194 Lymphoma Phase 2 Completed - United States, District of Col... More >>umbia Howard University Cancer Center at Howard University Hospital Washington, District of Columbia, United States, 20060 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Michigan Barbara Ann Karmanos Cancer Institute Detroit, Michigan, United States, 48201-1379 United States, Wisconsin University of Wisconsin Comprehensive Cancer Center Madison, Wisconsin, United States, 53792-5256 Less <<
NCT00019318 Lymphoma Phase 1 Completed - United States, Maryland ... More >> Medicine Branch Bethesda, Maryland, United States, 20892 Less <<
NCT00106613 Carcinoma, Renal Cell ... More >> Neoplasm Metastasis Less << Phase 2 Completed - United States, California ... More >> City of Hope National Medical Center Duarte, California, United States, 91010 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Washington Seattle Cancer Care Alliance Seattle, Washington, United States, 98109-1023 Less <<
NCT00007345 Cutaneous T Cell Lymphoma|Peri... More >>pheral T Cell Lymphoma Less << PHASE2 COMPLETED 2015-07-27 Mayo Clinic Scottsdale, Scotts... More >>dale, Arizona, 85259, United States|University of Arkansas, Little Rock, Arkansas, 72205, United States|City of Hope National Cancer Center, Duarte, California, 91010, United States|Mercy General Hospital, Sacramento, California, 95819, United States|Georgetown University, Washington, District of Columbia, 20007-2197, United States|Northwestern University, Chicago, Illinois, 60611, United States|National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, 20892, United States|North Shore University Hospital, Manhasset, New York, 11030, United States|University of Pittsburgh, Pittsburgh, Pennsylvania, 15261, United States|West Virginia University, Morgantown, West Virginia, 26506, United States|Royal Adelaide Hospital, Adelaide, Australia|Peter MacCallum Cancer Centre, Melbourne, Australia|Sir Charles Gairdner Hospital, Perth, Australia Less <<
NCT00066638 DS Stage II Plasma Cell Myelom... More >>a DS Stage III Plasma Cell Myeloma Refractory Plasma Cell Myeloma Less << Phase 2 Completed - United States, New York ... More >> Montefiore Medical Center - Moses Campus Bronx, New York, United States, 10467-2490 Less <<
NCT00077337 Colorectal Cancer Phase 2 Completed - -
NCT00431990 Multiple Myeloma Phase 1 Phase 2 Unknown January 2012 Australia, Victoria ... More >> Peter MacCallum Cancer Centre Recruiting Melbourne, Victoria, Australia, 8006 Sub-Investigator: Alvin Milner Less <<
NCT00053963 Blastic Phase Chronic Myelogen... More >>ous Leukemia Childhood Central Nervous System Germ Cell Tumor Childhood Choroid Plexus Tumor Childhood Chronic Myelogenous Leukemia Childhood Craniopharyngioma Childhood Grade I Meningioma Childhood Grade II Meningioma Childhood Grade III Meningioma Childhood High-grade Cerebral Astrocytoma Childhood Infratentorial Ependymoma Childhood Low-grade Cerebral Astrocytoma Childhood Spinal Cord Neoplasm Childhood Supratentorial Ependymoma Recurrent Childhood Acute Lymphoblastic Leukemia Recurrent Childhood Acute Myeloid Leukemia Recurrent Childhood Brain Stem Glioma Recurrent Childhood Cerebellar Astrocytoma Recurrent Childhood Cerebral Astrocytoma Recurrent Childhood Ependymoma Recurrent Childhood Medulloblastoma Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor Recurrent Childhood Visual Pathway and Hypothalamic Glioma Refractory Chronic Lymphocytic Leukemia Relapsing Chronic Myelogenous Leukemia Unspecified Childhood Solid Tumor, Protocol Specific Less << Phase 1 Completed - United States, California ... More >> Children's Oncology Group Arcadia, California, United States, 91006-3776 Less <<
NCT01742793 Hodgkin's Lymphoma ... More >> Mature T-cell Lymphoma Multiple Myeloma Less << Phase 1 Phase 2 Terminated - United States, Connecticut ... More >> Yale Cancer Center New Haven, Connecticut, United States, 06519 Less <<
NCT00383565 Recurrent Adult Diffuse Large ... More >>Cell Lymphoma Recurrent Mantle Cell Lymphoma Less << Phase 2 Terminated - United States, Texas ... More >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT03041012 Hiv Phase 2 Recruiting August 20, 2019 Denmark ... More >> Department of Infectious Diseases Recruiting Aalborg, Denmark Contact: Henrik Nielsen ?? ?? ?? Dept. of Infectious Diseases, Aarhus University Hospital Recruiting Aarhus, Denmark, 8200 Contact: Jesper D Gunst, MD ?? +45 78452844 ?? jesdam@rm.dk ?? Department of Infectious Diseases Recruiting Hvidovre, Denmark Contact: Thomas Benfield ?? ?? ?? Department of Infectious Diseases Recruiting K?benhavn, Denmark Contact: Jan Gerstoft ?? ?? ?? Department of Infectious Diseases Recruiting Odense, Denmark Contact: Isik S. Johansen ?? ?? ?? United Kingdom Imperial College Healthcare NHS Trust Recruiting London, United Kingdom Contact: Amin Aamshah ?? ?? ?? Principal Investigator: Sarah Fidler Less <<
NCT00007345 Cutaneous T Cell Lymphoma|Peri... More >>pheral T Cell Lymphoma Less << PHASE2 COMPLETED 2015-07-27 Mayo Clinic Scottsdale, Scotts... More >>dale, Arizona, 85259, United States|University of Arkansas, Little Rock, Arkansas, 72205, United States|City of Hope National Cancer Center, Duarte, California, 91010, United States|Mercy General Hospital, Sacramento, California, 95819, United States|Georgetown University, Washington, District of Columbia, 20007-2197, United States|Northwestern University, Chicago, Illinois, 60611, United States|National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, 20892, United States|North Shore University Hospital, Manhasset, New York, 11030, United States|University of Pittsburgh, Pittsburgh, Pennsylvania, 15261, United States|West Virginia University, Morgantown, West Virginia, 26506, United States|Royal Adelaide Hospital, Adelaide, Australia|Peter MacCallum Cancer Centre, Melbourne, Australia|Sir Charles Gairdner Hospital, Perth, Australia Less <<
NCT02061449 Cutaneous T-cell Lymphoma Phase 1 Active, not recruiting March 2019 United States, New York ... More >> NYU Cancer Institute New York, New York, United States, 10016 Less <<
NCT00383565 - Terminated - -
NCT00087295 Bladder Cancer ... More >> Transitional Cell Cancer of the Renal Pelvis and Ureter Urethral Cancer Less << Phase 2 Terminated(Permanently Closed ... More >>Due to Poor Accrual) Less << - -
NCT00106301 Carcinoma, Renal Cell ... More >> Prostatic Neoplasms Less << Phase 2 Completed - United States, California ... More >> City of Hope National Medical Center Duarte, California, United States, 91010-3000 United States, Florida University of Florida Gainesville, Florida, United States, 32610 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637-1470 United States, Washington Seattle Cancer Care Alliance Seattle, Washington, United States, 98109 United Kingdom Royal Marsden Hospital Sutton, United Kingdom, SM2 5PT Less <<
NCT00048334 Neoplasms Phase 1 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT02181218 Lymphoma, T-Cell, Cutaneous ... More >> Lymphoma, T-Cell, Peripheral Hodgkin Disease Lymphoma, Large B-Cell, Diffuse Less << Phase 1 Recruiting June 30, 2020 United States, California ... More >> University of California - San Francisco Not yet recruiting San Francisco, California, United States, 94143 Contact: Weiyun Ai, M.D., Ph.D. ?? 415-353-4061 ?? weiai@medicine.ucsf.edu ?? Principal Investigator: Weiyun Ai, M.D., Ph.D. ?? ?? ?? United States, Illinois University of Chicago Recruiting Chicago, Illinois, United States, 60637 Contact: Peter Riedell, M.D. ?? 773-753-3288 ?? ?? Principal Investigator: Peter Riedell, M.D. ?? ?? ?? Sub-Investigator: Justin Kline, M.D. ?? ?? ?? Sub-Investigator: Sonali Smith, M.D. ?? ?? ?? Sub-Investigator: Kenneth Cohen, M.D. ?? ?? ?? Sub-Investigator: Michael Bishop, M.D. ?? ?? ?? United States, Missouri Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Neha Mehta-Shah, M.D. ?? 314-747-7402 ?? mehta-n@wustl.edu ?? Principal Investigator: Neha Mehta-Shah, M.D. ?? ?? ?? Sub-Investigator: Nancy Bartlett, M.D. ?? ?? ?? Sub-Investigator: Todd Fehniger, M.D., Ph.D. ?? ?? ?? Sub-Investigator: Amanda Cashen, M.D. ?? ?? ?? Sub-Investigator: Brad Kahl, M.D. ?? ?? ?? Sub-Investigator: Peter Riedell, M.D. Less <<
NCT00098527 Adenocarcinoma of the Esophagu... More >>s Adenocarcinoma of the Stomach Recurrent Esophageal Cancer Recurrent Gastric Cancer Less << Phase 2 Terminated - United States, North Carolina ... More >> Duke University Medical Center Durham, North Carolina, United States, 27710 Less <<
NCT00098397 Male Breast Cancer ... More >> Recurrent Breast Cancer Stage IV Breast Cancer Less << Phase 2 Completed - United States, Texas ... More >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT02092116 HIV I Infection Phase 1 Phase 2 Completed - Denmark ... More >> Aarhus University Hospital, Skejby Sygehus Aarhus N, Denmark, 8200 Less <<
NCT00106418 Prostate Cancer|Metastases PHASE2 COMPLETED 2006-09-01 -
NCT01590732 Mycosis Fungoides ... More >> Recurrent Anaplastic Large Cell Lymphoma Recurrent Angioimmunoblastic T-Cell Lymphoma Recurrent Enteropathy-Associated T-Cell Lymphoma Recurrent Hepatosplenic T-Cell Lymphoma Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified Refractory Anaplastic Large Cell Lymphoma Refractory Angioimmunoblastic T-Cell Lymphoma Refractory Enteropathy-Associated T-Cell Lymphoma Refractory Hepatosplenic T-Cell Lymphoma Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified Less << Phase 1 Completed - United States, Texas ... More >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT02092116 - Completed - -
NCT02783625 Lymphoma Rela... More >>psed/Refractory T-cell Lymphomas Less << Phase 1 Recruiting May 2019 United States, California ... More >> Stanford University Medical Center Recruiting Stanford, California, United States, 94305-5408 Contact: Youn Kim, MD ?? 650-498-6000 ?? ?? United States, Massachusetts Dana Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02115 Contact: Eric Jacobsen, MD ?? 617-582-9086 ?? ?? United States, Missouri University of Washington School of Medicine in St. Louis Recruiting Saint Louis, Missouri, United States, 63110 Contact: Neha Mehta-Shah, MD ?? 314-362-5654 ?? ?? Principal Investigator: Neha Mehta-Shah, MD ?? ?? ?? Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Neha Mehta-Shah, MD ?? 314-362-5654 ?? ?? Principal Investigator: Neha Mehta-Shah, MD ?? ?? ?? United States, New Jersey Memoral Sloan Kettering Cancer Center Basking Ridge Recruiting Basking Ridge, New Jersey, United States Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Memorial Sloan Kettering Monmouth Recruiting Middletown, New Jersey, United States, 07748 Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? United States, New York Memorial Sloan Kettering Cancer Center @ Commack Recruiting Commack, New York, United States, 11725 Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Memoral Sloan Kettering Westchester Recruiting Harrison, New York, United States Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Contact: Alison Moskowitz, MD ?? 212-639-4839 ?? ?? Principal Investigator: Steven Horwitz, MD ?? ?? ?? Memorial Sloan Kettering at Mercy Medical Center Recruiting Rockville Centre, New York, United States Contact: Steven Horwitz, MD ?? 212-639-3045 Less <<
NCT00098813 - Completed - -
NCT00084682 - Completed - -
NCT00062075 Adult Acute Myeloid Leukemia W... More >>ith 11q23 (MLL) Abnormalities Adult Acute Myeloid Leukemia With Del(5q) Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) Adult Acute Promyelocytic Leukemia (M3) Recurrent Adult Acute Myeloid Leukemia Less << Phase 2 Completed - United States, Illinois ... More >> University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637-1470 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States, 37232 Less <<
NCT00098813 Recurrent Thyroid Cancer ... More >> Stage IV Follicular Thyroid Cancer Stage IV Papillary Thyroid Cancer Less << Phase 2 Completed - United States, New York ... More >> Memorial Sloan-Kettering Cancer Center at Suffolk Commack, New York, United States, 11725 Less <<
NCT00086827 Recurrent Small Cell Lung Canc... More >>er Less << Phase 2 Completed - United States, Ohio ... More >> Ohio State University Columbus, Ohio, United States, 43210 Less <<
NCT00106431 Cutaneous T-cell Lymphoma Phase 2 Completed - United States, California ... More >> UCLA Jonsson Cancer Center Los Angeles, California, United States, 90095 Stanford Comprehensive Cancer Center Stanford, California, United States, 94305 United States, Massachusetts Boston Medical Center Boston, Massachusetts, United States, 02118 United States, Pennsylvania University of Pennsylvania Abrahamson Cancer Center Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee Vanderbilt-Ingram Cancer Center Nashville, Tennessee, United States, 37232 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 France Research Site Various Cities, France Germany Research Site Various Cities, Germany Poland Research Site Various Cities, Poland Russian Federation Research Site Various Cities, Russian Federation United Kingdom Research Site Various Cities, United Kingdom Less <<
NCT00084682 Stage IV Squamous Cell Carcino... More >>ma of the Hypopharynx Stage IV Squamous Cell Carcinoma of the Larynx Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity Stage IV Squamous Cell Carcinoma of the Oropharynx Less << Phase 2 Completed - United States, Massachusetts ... More >> Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, New York Montefiore Medical Center Bronx, New York, United States, 10467-2490 Less <<
NCT00106431 - Completed - -
NCT01280526 Peripheral T Cell Lymphoma Phase 1 Phase 2 Completed - France ... More >> H?pital Henri Mondor Créteil, France, 94010 CHU de Dijon Dijon, France, 21000 H?pital Claude Huriez Lille, France, 59037 Centre Léon Bérard Lyon cedex 8, France, 69373 H?pital St Louis Paris, France, 75475 Centre Hospitalier Lyon Sud Pierre-Bénite, France, 69495 Centre Henri Becquerel Rouen, France, 76038 Institut Gustave Roussy Villejuif, France, 94805 Less <<
NCT00084461 Gastrinoma Gl... More >>ucagonoma Insulinoma Metastatic Gastrointestinal Carcinoid Tumor Pancreatic Polypeptide Tumor Pulmonary Carcinoid Tumor Recurrent Gastrointestinal Carcinoid Tumor Recurrent Islet Cell Carcinoma Regional Gastrointestinal Carcinoid Tumor Somatostatinoma Less << Phase 2 Terminated - United States, Ohio ... More >> Ohio State University Medical Center Columbus, Ohio, United States, 43210 Less <<
NCT03161223 Lymphoma, T-Cell Phase 1 Phase 2 Recruiting June 30, 2020 United States, New York ... More >> Center for Lymphoid Malignancies at CUMC Recruiting New York, New York, United States, 10019 Contact: Michelle Malanga, MPA ?? ?? ?? Principal Investigator: Owen A O'Connor, M.D., PhD ?? ?? ?? Sub-Investigator: Jennifer E Amengual, M.D. ?? ?? ?? Sub-Investigator: Ahmed Sawas, M.D. ?? ?? ?? Sub-Investigator: Changchun Deng, M.D. ?? ?? ?? Sub-Investigator: Lorenzo Falchi, M.D. ?? ?? ?? Italy University of Bologna Not yet recruiting Bologna, Italy Principal Investigator: Pier Luigi Zinzani, M.D., PhD. ?? ?? ?? Korea, Republic of Samsung Medical Center Not yet recruiting Seoul, Korea, Republic of Principal Investigator: Won Seog Kim, M.D., Ph.D. Less <<
NCT00091195 Primary Peritoneal Cavity Canc... More >>er Recurrent Ovarian Epithelial Cancer Less << Phase 2 Terminated(Administratively co... More >>mplete.) Less << - United States, North Carolina ... More >> High Point Regional Hospital High Point, North Carolina, United States, 27261 Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 Less <<
NCT01302808 Lung Cancer M... More >>etastatic Cancer Less << Phase 1 Phase 2 Completed - United States, Texas ... More >> Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas Dallas, Texas, United States, 75390 Less <<
NCT00085527 Ovarian Cancer Phase 2 Withdrawn - United States, Illinois ... More >> Cardinal Bernardin Cancer Center at Loyola University Medical Center Maywood, Illinois, United States, 60153 Less <<
NCT00104884 Malignant Melanoma ... More >> Melanoma Less << Phase 2 Terminated(The study was termi... More >>nated on May 17, 2006 due to slow accrual.) Less << - -
NCT01933594 HIV Infections Phase 1 Phase 2 Completed - United States, Alabama ... More >> Alabama CRS Birmingham, Alabama, United States, 35294 United States, California UCLA CARE Center CRS Los Angeles, California, United States, 90035 United States, Colorado University of Colorado Hospital CRS Aurora, Colorado, United States, 80045 United States, Massachusetts Massachusetts General Hospital CRS (MGH CRS) Boston, Massachusetts, United States, 02114 United States, New York University of Rochester Adult HIV Therapeutic Strategies Network CRS Rochester, New York, United States, 14642 United States, North Carolina Chapel Hill CRS Chapel Hill, North Carolina, United States, 27599 United States, Ohio Ohio State University CRS Columbus, Ohio, United States, 43210 United States, Pennsylvania Penn Therapeutics, CRS Philadelphia, Pennsylvania, United States, 19104 University of Pittsburgh CRS Pittsburgh, Pennsylvania, United States, 15213 United States, Washington University of Washington AIDS CRS Seattle, Washington, United States, 98104-9929 Less <<
NCT00379639 - Completed - -
NCT00112463 - Completed - -
NCT00104884 - Terminated(The study was termi... More >>nated on May 17, 2006 due to slow accrual.) Less << - -
NCT02281279 B-cell Adult Acute Lymphoblast... More >>ic Leukemia Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Intraocular Lymphoma Nodal Marginal Zone B-cell Lymphoma Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Burkitt Lymphoma Recurrent Adult Diffuse Large Cell Lymphoma Recurrent Adult Diffuse Mixed Cell Lymphoma Recurrent Adult Diffuse Small Cleaved Cell Lymphoma Recurrent Adult Grade III Lymphomatoid Granulomatosis Recurrent Adult Immunoblastic Large Cell Lymphoma Recurrent Adult Lymphoblastic Lymphoma Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Recurrent Small Lymphocytic Lymphoma Refractory Hairy Cell Leukemia Small Intestine Lymphoma Splenic Marginal Zone Lymphoma Testicular Lymphoma Waldenstr?m Macroglobulinemia Less << Phase 1 Phase 2 Withdrawn - -
NCT02341014 T-cell Lymphomas ... More >> Relapsed or Refractory Less << Phase 1 Phase 2 Active, not recruiting January 2019 United States, Nebraska ... More >> University of Nebraska Medical Center Omaha, Nebraska, United States, 68198-7680 United States, New Jersey Memoral Sloan Kettering Cancer Center Basking Ridge, New Jersey, United States, 07920 United States, New York Memorial Sloan Kettering Cancer Center @ Suffolk Commack, New York, United States, 11725 Memorial Sloan Kettering Westchester Harrison, New York, United States, 10604 Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Memorial Sloan Kettering at Mercy Medical Center Rockville Centre, New York, United States, 11570 Less <<
NCT00112463 Adult Alveolar Soft-part Sarco... More >>ma Adult Angiosarcoma Adult Epithelioid Sarcoma Adult Extraskeletal Chondrosarcoma Adult Extraskeletal Osteosarcoma Adult Fibrosarcoma Adult Leiomyosarcoma Adult Liposarcoma Adult Malignant Fibrous Histiocytoma Adult Malignant Hemangiopericytoma Adult Malignant Mesenchymoma Adult Neurofibrosarcoma Adult Rhabdomyosarcoma Adult Synovial Sarcoma Gastrointestinal Stromal Tumor Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Recurrent Adult Soft Tissue Sarcoma Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Stage III Adult Soft Tissue Sarcoma Stage IV Adult Soft Tissue Sarcoma Less << Phase 2 Completed - -
NCT00085540 Adult Anaplastic Astrocytoma ... More >> Adult Anaplastic Oligodendroglioma Adult Giant Cell Glioblastoma Adult Gliosarcoma Recurrent Adult Brain Tumor Less << Phase 1 Phase 2 Completed - United States, California ... More >> University of California Los Angeles Los Angeles, California, United States, 90095 University of California San Francisco San Francisco, California, United States, 94143 United States, Maryland National Cancer Institute Neuro-Oncology Branch Bethesda, Maryland, United States, 20814 United States, Massachusetts Dana Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, New York Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15232 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 United States, Wisconsin University of Wisconsin Madison, Wisconsin, United States, 53792 Less <<
NCT03742921 - Not yet recruiting April 17, 2023 -
NCT00379639 Pancreatic Cancer Phase 1 Completed - United States, Tennessee ... More >> Sarah Cannon Research Institute Nashville, Tennessee, United States, 37203 Less <<
NCT00085540 - Completed - -
NCT01902225 Lymphoma T-Ce... More >>ll Lymphoma Cutaneous Lymphoma Less << Phase 1 Recruiting April 2019 United States, California ... More >> UCSF Helen Diller Family Comprehensive Cancer Center Recruiting San Francisco, California, United States, 94115 Contact: Weiyun Ai, MD, PHD ?? 415-353-4061 ?? weiyun.ai@ucsf.edu ?? Principal Investigator: Weiyun Ai, MD, PhD ?? ?? ?? United States, Ohio Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Jonathan Branmmer, MD ?? 614-293-2268 ?? Jonathan.Brammer@osumc.edu Less <<
NCT01897012 MYC Positive ... More >>Recurrent B-Cell Non-Hodgkin Lymphoma Recurrent Burkitt Lymphoma Recurrent Diffuse Large B-Cell Lymphoma Recurrent Follicular Lymphoma Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements Recurrent Hodgkin Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma Refractory B-Cell Non-Hodgkin Lymphoma Refractory Burkitt Lymphoma Refractory Diffuse Large B-Cell Lymphoma Refractory Follicular Lymphoma Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements Refractory Hodgkin Lymphoma Refractory Mantle Cell Lymphoma Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma Less << Phase 1 Active, not recruiting - United States, Texas ... More >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT00963274 Leukemia Lymp... More >>homa Less << Phase 1 Completed - United States, Illinois ... More >> Robert H. Lurie Comprehensive Cancer Center, Northwestern University Chicago, Illinois, United States, 60611 United States, Maryland University of Maryland Greenebaum Cancer Center Baltimore, Maryland, United States, 21201 United States, North Carolina University of North Carolina Chapel Hill, North Carolina, United States, 27599 United States, Tennessee Vanderbilt-Ingram Cancer Center, Vanderbilt University Nashville, Tennessee, United States, 37232 United States, Virginia Virginia Commonwealth University/Massey Cancer Center Richmond, Virginia, United States, 23298 Less <<
NCT01908777 T Cell Non-Hodgkin Lymphoma Phase 2 Recruiting July 2020 United States, Florida ... More >> Moffitt Cancer Center Recruiting Tampa, Florida, United States, 33612 Contact: Farhad Khimani, MD ?? ?? ?? Contact ?? 1-888-663-3488 ?? ?? Principal Investigator: Farhad Khimani, MD ?? ?? ?? United States, New Jersey Memoral Sloan Kettering Cancer Center Recruiting Basking Ridge, New Jersey, United States Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Memorial Sloan Kettering Monmouth Recruiting Middletown, New Jersey, United States, 07748 Contact: Steve Horwitz, MD ?? 212-639-3045 ?? ?? United States, New York Memorial Sloan Kettering Cancer Center @ Suffolk Recruiting Commack, New York, United States, 11725 Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Memorial Sloan Kettering Westchester Recruiting Harrison, New York, United States, 10604 Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 11065 Contact: Steven Horwitz, MD ?? 212-639-3045 ?? ?? Contact: Parastoo Dahi, MD ?? 212-639-5846 ?? ?? Principal Investigator: Steven Horwitz, MD ?? ?? ?? Weill Cornell Medical Center Recruiting New York, New York, United States Contact: Jia Ruan, MD ?? ?? ?? Principal Investigator: Jia Ruan, MD ?? ?? ?? Memorial Sloan Kettering at Mercy Medical Center Recruiting Rockville Centre, New York, United States Contact: Steven Horwitz, MD ?? ?? ?? United States, Washington University of Washington School of Medicine Recruiting Seattle, Washington, United States, 98109 Contact: Andrei Shustov, MD ?? ?? ?? Principal Investigator: Andrei Shustov, MD Less <<
NCT01796002 Peripheral T-cell Lymphoma Phase 3 Active, not recruiting July 2024 -
NCT02232516 Adult Nasal Type Extranodal NK... More >>/T-cell Lymphoma Anaplastic Large Cell Lymphoma Angioimmunoblastic T-cell Lymphoma Hepatosplenic T-cell Lymphoma Peripheral T-cell Lymphoma Stage I Cutaneous T-cell Non-Hodgkin Lymphoma Stage IA Mycosis Fungoides/Sezary Syndrome Stage IB Mycosis Fungoides/Sezary Syndrome Stage II Cutaneous T-cell Non-Hodgkin Lymphoma Stage IIA Mycosis Fungoides/Sezary Syndrome Stage IIB Mycosis Fungoides/Sezary Syndrome Stage III Cutaneous T-cell Non-Hodgkin Lymphoma Stage IIIA Mycosis Fungoides/Sezary Syndrome Stage IIIB Mycosis Fungoides/Sezary Syndrome Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma Stage IVA Mycosis Fungoides/Sezary Syndrome Stage IVB Mycosis Fungoides/Sezary Syndrome Less << Phase 2 Recruiting August 2020 United States, California ... More >> City of Hope Recruiting Duarte, California, United States, 91010 Contact: Jasmine Zain, MD ?? 626-256-4673 ?? ?? Principal Investigator: Jasmine Zain, MD ?? ?? ?? United States, Connecticut Yale University Not yet recruiting New Haven, Connecticut, United States, 06520 Contact: Francine M. Foss, MD ?? 203-200-4363 ?? ?? Principal Investigator: Francine M. Foss, MD ?? ?? ?? United States, Illinois Northwestern University Recruiting Chicago, Illinois, United States, 60611 Contact: Adam M. Petrich, MD ?? 312-695-4537 ?? ?? Principal Investigator: Adam M. Petrich, MD ?? ?? ?? United States, New York Weill Cornell Medicine Recruiting New York, New York, United States, 10021 Contact: Jia Ruan, MD ?? 646-962-2064 ?? ?? Principal Investigator: Jia Ruan, MD ?? ?? ?? United States, Washington Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium Not yet recruiting Seattle, Washington, United States, 98109 Contact: Andrei R. Shustov ?? 206-288-6739 ?? ?? Principal Investigator: Andrei R. Shustov, MD Less <<
NCT02616874 HIV Phase 1 Completed - Spain ... More >> Germans Trias i Pujol Hospital Badalona, Barcelona, Spain, 08916 Clinic Hospital Barcelona, Spain, 08036 Less <<
NCT02616965 Cutaneous T-cell Lymphoma (CTC... More >>L) Less << Phase 1 Recruiting July 2021 United States, Pennsylvania ... More >> Fox Chase Cancer Center Recruiting Philadelphia, Pennsylvania, United States, 19111 Contact: Stefan K. Barta, MD ?? 215-728-2674 ?? ?? Principal Investigator: Stefan K. Barta, MD Less <<
NCT01947140 Lymphoid Malignancies ... More >> Multiple Myeloma Lymphoma Hodgkin Lymphoma Non-hodgkin Lymphoma Less << Phase 1 Phase 2 Recruiting December 2018 United States, New York ... More >> Columbia University Medical Center Recruiting New York, New York, United States, 10019 Contact: Renee Lichtenstein ?? 212-326-5720 ?? rl2619@cumc.columbia.edu ?? Principal Investigator: Jennifer E Amengual, MD Less <<
NCT01456039 Lymphoma, T-cell, Peripheral PHASE1|PHASE2 COMPLETED 2018-12-14 Nagoya Daini Red Cross Hospita... More >>l, Nagoya, Aichi, 466-8650, Japan|Nagoya City University Hospital, Nagoya, Aichi, 467-8602, Japan|National Cancer Center Hospital East, Kashiwa, Chiba, 277-8577:, Japan|Ehime University Hospital, To-on, Ehime, 791-0295, Japan|Chugoku Central Hospital, Fukuyamashi, Hiroshima, 720-0001, Japan|Sapporo Hokuyu Hospital, Sapporo, Hokkaido, 003-0006, Japan|Sapporo Medical University Hospital, Sapporo, Hokkaido, 060-8543, Japan|Tokai University School of Medicine, Isehara, Kanagawa, 259-1193, Japan|Kochi Medical School Hospital, Nankoku, Kochi, 783-8505, Japan|Kinki University Hospital, Sayama, Osaka, 589-8511, Japan|National Cancer Center Hospital, Chuo, Tokyo, 104-0045, Japan|Japanese Red Cross Medical Center, Shibuya, Tokyo, 150-8935, Japan|Kyushu University Hospital, Fukuoka, 812-8582, Japan|Kumamoto University Hospital, Kumamoto, 860-8556, Japan|University hospital, Kyoto prefectural University of Medicine, Kyoto, 602-8566, Japan|Tohoku University Hospital, Miyagi, 980-8574, Japan|The Cancer Institute Hospital of JFCR, Tokyo, 135-8550, Japan Less <<
NCT02757248 PTCL CTCL Phase 1 Withdrawn(Boehringer Ingelheim... More >> is discontinuing their volasertib development program) Less << - -
NCT01456039 Lymphoma, T-cell, Peripheral PHASE1|PHASE2 COMPLETED 2018-12-14 Nagoya Daini Red Cross Hospita... More >>l, Nagoya, Aichi, 466-8650, Japan|Nagoya City University Hospital, Nagoya, Aichi, 467-8602, Japan|National Cancer Center Hospital East, Kashiwa, Chiba, 277-8577:, Japan|Ehime University Hospital, To-on, Ehime, 791-0295, Japan|Chugoku Central Hospital, Fukuyamashi, Hiroshima, 720-0001, Japan|Sapporo Hokuyu Hospital, Sapporo, Hokkaido, 003-0006, Japan|Sapporo Medical University Hospital, Sapporo, Hokkaido, 060-8543, Japan|Tokai University School of Medicine, Isehara, Kanagawa, 259-1193, Japan|Kochi Medical School Hospital, Nankoku, Kochi, 783-8505, Japan|Kinki University Hospital, Sayama, Osaka, 589-8511, Japan|National Cancer Center Hospital, Chuo, Tokyo, 104-0045, Japan|Japanese Red Cross Medical Center, Shibuya, Tokyo, 150-8935, Japan|Kyushu University Hospital, Fukuoka, 812-8582, Japan|Kumamoto University Hospital, Kumamoto, 860-8556, Japan|University hospital, Kyoto prefectural University of Medicine, Kyoto, 602-8566, Japan|Tohoku University Hospital, Miyagi, 980-8574, Japan|The Cancer Institute Hospital of JFCR, Tokyo, 135-8550, Japan Less <<
NCT01998035 Lymphoid Malignancies ... More >> Lymphoma Hodgkin Lymphoma Non-hodgkin Lymphoma Less << Phase 1 Phase 2 Recruiting February 2019 United States, New York ... More >> Columbia University Medical Center Recruiting New York, New York, United States, 10019 Contact: Celeste Rojas ?? 212-326-5720 ?? cr2393@cumc.columbia.edu ?? Principal Investigator: Owen A O'Connor, MD, Ph.D. Less <<
NCT01445340 Mycosis Fungoides ... More >> Cutaneous T-Cell Lymphoma Neoplasms Less << Phase 1 Terminated - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT00765102 - Terminated(There was a change ... More >>in the Sponsor's research strategy; safety concerns were not a factor.) Less << - -
NCT02393794 Triple-Negative Breast Cancer ... More >> Breast Cancer Less << Phase 1 Phase 2 Recruiting July 2020 United States, Kansas ... More >> University of Kansas Cancer Center - Clinical Research Center Recruiting Fairway, Kansas, United States, 66205 Contact: Priyanka Sharma, MD ?? 913-588-6029 ?? psharma2@kumc.edu ?? Contact: Clinical Trials Nurse Navigator ?? 913-945-7552 ?? ctnursenav@kumc.edu ?? University of Kansas Cancer Center - West Recruiting Kansas City, Kansas, United States, 66112 Contact: Clinical Trials Nurse Navigator ?? 913-945-7552 ?? ctnursenav@kumc.edu ?? University of Kansas Cancer Center - Overland Park Recruiting Overland Park, Kansas, United States, 66210 Contact: Clinical Trials Nurse Navigator ?? 913-945-7552 ?? ctnursenav@kumc.edu ?? University of Kansas Cancer Center - Westwood Recruiting Westwood, Kansas, United States, 66205 Contact: Clinical Trials Nurse Navigator ?? 913-945-7552 ?? ctnursenav@kumc.edu ?? United States, Missouri University of Kansas Cancer Center - South Recruiting Kansas City, Missouri, United States, 64131 Contact: Clinical Trials Nurse Navigator ?? 913-945-7552 ?? ctnursenav@kumc.edu ?? University of Kansas Cancer Center - North Recruiting Kansas City, Missouri, United States, 64154 Contact: Clinical Trials Nurse Navigator ?? 913-945-7552 ?? ctnursenav@kumc.edu ?? University of Kansas Cancer Center - Lee's Summit Recruiting Lee's Summit, Missouri, United States, 64064 Contact: Clinical Trials Nurse Navigator ?? 913-945-7552 ?? ctnursenav@kumc.edu Less <<
NCT00426764 Peripheral T-cell Lymphoma PHASE2 COMPLETED 2018-05-17 Moore UCSD Cancer Center, La J... More >>olla, California, 92093, United States|UCLA Division of Hematology Oncology, Los Angeles, California, 90095, United States|University of California, San Francisco, San Francisco, California, 94143-0324, United States|Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, 80012, United States|Yale University, New Haven, Connecticut, 06519, United States|Georgetown University IRB, Washington, District of Columbia, 20007, United States|Washington Hospital Center, Washington, District of Columbia, 20010, United States|Cancer Centers of Florida, PA, Orlando, Florida, 32806-1124, United States|H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, 33612-9416, United States|Winship Cancer Institute of Emory University, Atlanta, Georgia, 30322, United States|Augusta Oncology Associates, P.C., Augusta, Georgia, 30901, United States|Central Georgia Cancer Care, Macon, Georgia, 31201, United States|Cancer Care and Hematology Specialists of Chicagoland, Arlington Heights, Illinois, 60005, United States|Hematology Oncology Assoc. of IL Orchard Research LLC, Chicago, Illinois, 60611, United States|Rush University Medical Center, Chicago, Illinois, 60612, United States|Consultants in Blood Disorders and Cancer, Louisville, Kentucky, 40207, United States|St. Agnes - Medical Center, Baltimore, Maryland, 21229-5299, United States|Center for Cancer And Blood Disorders, Bethesda, Maryland, 20817, United States|Center for Cancer Research CAMC, Bethesda, Maryland, 20892, United States|Tufts Medical Center, Boston, Massachusetts, 02111, United States|Henry Ford Hospital, Detroit, Michigan, 48202, United States|Minnesota Oncology Hematology, PA, Burnsville, Minnesota, 55337, United States|St. Joseph Oncology, Inc, Saint Joseph, Missouri, 64507, United States|Arch Medical Services, Saint Louis, Missouri, 63141, United States|Nebraska Cancer Specialists, Omaha, Nebraska, 68114, United States|Hackensack University Medical Center, Hackensack, New Jersey, 07601, United States|Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, United States|Weill Cornell Medical College, New York, New York, 10021, United States|Columbia University Medical Center, New York, New York, 10032, United States|Taussig Cancer Center Cleveland Clinic Foundation, Cleveland, Ohio, 44195, United States|Northwest Cancer Specialists, P.C., Portland, Oregon, 97227, United States|Accelerated Community Oncology Research Network Inc ACORN, Memphis, Tennessee, 38138, United States|Mamie McFadden Ward Center, Beaumont, Texas, 77702-1449, United States|Methodist Charlton Cancer Center, Dallas, Texas, 75237, United States|UT Southwestern Medical Center Simmons Comprehensive Cancer Center, Dallas, Texas, 75390-8565, United States|El Paso Cancer Treatment Center, El Paso, Texas, 79915, United States|Texas Oncology, P.A.-Fort Worth, Fort Worth, Texas, 76104, United States|UT MD Anderson Cancer Center, Houston, Texas, 77030-4009, United States|Allison Cancer Center, Midland, Texas, 79701, United States|US Oncology, Plano, Texas, 75093, United States|HOAST, San Antonio, Texas, 78229, United States|University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229, United States|Tyler Cancer Center, Tyler, Texas, 75702, United States|Texas Oncology, PA, Waco, Texas, 76712, United States|Fred Hutchinson Cancer Research Center, Seattle, Washington, 98109-1024, United States|Mater Private Medical Centre - Haematology and Oncology Clinics of Australasia Research Centre, South Brisbane, Queensland, 4101, Australia|Peter MacCallum Cancer Centre, East Melbourne, 3002, Australia|St. Vincent Hospital, Fitzroy, 3065, Australia|Royal North Shore Hospital, St Leonards, 2065, Australia|University Hospital Brno, Brno, 625 00, Czechia|University Hospital Hradec Kralove, Hradec Kralove, 500 05, Czechia|University Hospital of Kralovske Vinohrady, Prague 10, 100 34, Czechia|Charles University General Hospital, Prague 2, 128 08, Czechia|Polyclinique Bordeaux Nord Aquitaine, Bordeaux, 33000, France|Hopital Henri Mondor, Créteil, 94010, France|Hopital Claude Huriez, Lille, 59037, France|CHU Nantes Hotel Dieu, Nantes, 44093, France|Hopital Saint-Louis, Paris, 75010, France|Service des Maladies du Sang, Pessac, 33604, France|Centre Hospitalier Lyon Sud, Pierre Bénite, 69495, France|Centre Eugene Marquis, Rennes, 35033, France|Centre Henri Becquerel, Rouen Cedex, 79038, France|Charite Universitatsmedizin Berlin campus Virchow Klinikum Centrum fur Tumormedizin, Berlin, 13353, Germany|Krankenhaus Nordwest, Frankfurt a.M., 60488, Germany|Georg-August-Universit?t G?ttingen, G?ttingen, 37075, Germany|Uniklinik Koln, K?ln, 50937, Germany|Klinikum der Universitat Munchen-Grosshadern, Muenchen, D-81377, Germany|Klinikum Nurnberg Nord, Nürnberg, D- 90419, Germany|UKT Universitaetsklinikum Tuebingen, Tuebingen, 72076, Germany|Klinika Hematologii Akademickie Centrum Kliniczne Akademii Medycznej w Gdansku, Gdansk, 80-952, Poland|Oddzial Kliniczny Kliniki Hematologii, Kraków, 31 501, Poland|Wojewodzki Szpital Specjalistczny im. Mikolaja Kopernika, Lodz, 93-510, Poland|Klinika Nowotworow Ukladu Chlonnego, Warszawa, 02 781, Poland|Hospital Universitario Vall D Hebron, Barcelona, 08035, Spain|Hospital de La Princesa, Madrid, 28006, Spain|Hospital Universitario La Paz, Madrid, 28046, Spain|Clinica Universitaria de Navarra, Pamplona, 31008, Spain|Hospital Universitario de Salamanca, Salamanca, 37003, Spain|Hospital Marques de Valdecilla, Santandar, 39008, Spain|Lund University Hosptial, Lund, 22185, Sweden|Akademiska Sjukhuset, Uppsala, 75185, Sweden|Dnipropetrovsk State Medical Academy, Dnipropetrovsk, 49102, Ukraine|National Cancer Institute Department Of Conservative Methods Of Treatment, Kyiv, 03022, Ukraine|R.E.Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv, 03115, Ukraine|Institute of Blood Pathology and Transfusion Medicine of the AMS of Ukraine, Lviv, 79044, Ukraine|Royal Free Hospital, London Hampstead, NW3 2QG, United Kingdom|Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1A 7BE, United Kingdom|Guy's and St. Thomas' Hospital, London, SE1 9RT, United Kingdom|Catherine Lewis Centre - Hematology Department, London, W12 0HS, United Kingdom|Somers Cancer Research Building, Southampton, SO16 6YD, United Kingdom Less <<
NCT00765102 Multiple Myeloma Phase 2 Terminated(There was a change ... More >>in the Sponsor's research strategy; safety concerns were not a factor.) Less << - United States, California ... More >> Loma Linda University Cancer Center Loma Linda, California, United States, 92354 Desert Cancer Care, Inc Rancho Mirage, California, United States, 92270 Santa Barbara Hematology Oncology Medical Group, Inc. Santa Barbara, California, United States, 93105 James R Berenson, MD, Inc. West Hollywood, California, United States, 90069 United States, Georgia Georgia Cancer Specialists I, PC Atlanta, Georgia, United States, 30341 United States, Maryland Center for Cancer and Blood Disorders Bethesda, Maryland, United States, 20817 United States, North Carolina Mecklenburg Medical Group Charlotte, North Carolina, United States, 28204 United States, Texas Baylor Sammons Cancer Center Dallas, Texas, United States, 75246 Dallas Oncology Consultants, P.A. Duncanville, Texas, United States, 75137 Oncology Consultants, P.A Houston, Texas, United States, 77024 United States, Utah Central Utah Clinic, PC Provo, Utah, United States, 84604 United States, Washington Virginia Mason Medical Centre Seattle, Washington, United States, 98101 Less <<
NCT01846390 Peripheral T-Cell Lymphoma ... More >> Diffuse Large B-Cell Lymphoma Less << Phase 1 Completed - Canada, Alberta ... More >> Tom Baker Cancer Centre Calgary, Alberta, Canada, T2N 4N2 Canada, British Columbia BCCA - Vancouver Cancer Centre Vancouver, British Columbia, Canada, V5Z 4E6 Canada, New Brunswick Regional Health Authority B, Zone 2 Saint John, New Brunswick, Canada, E2L 4L2 Canada, Nova Scotia QEII Health Sciences Centre Halifax, Nova Scotia, Canada, B3H 1V7 Canada, Ontario Odette Cancer Centre Toronto, Ontario, Canada, M4N 3M5 Univ. Health Network-Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Less <<
NCT01755975 Multiple Myeloma ... More >> Non-Hodgkin's Lymphoma Less << Phase 1 Phase 2 Active, not recruiting December 2019 United States, Connecticut ... More >> Saint Francis/Mount Sinai Regional Cancer Center Hartford, Connecticut, United States, 06105 United States, Nebraska University of Nebraska Medical Center Omaha, Nebraska, United States, 68198-7680 United States, New Jersey Memorial Sloan Kettering at Basking Ridge Basking Ridge, New Jersey, United States, 07920 United States, New York Memorial Sloan Kettering Cancer Center at Commack Commack, New York, United States, 11725 Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Weill Cornell Medical Center New York, New York, United States Memorial Sloan Kettering Cancer Center at Mercy Rockville Centre, New York, United States, 11570 Less <<
NCT00426764 Peripheral T-cell Lymphoma PHASE2 COMPLETED 2018-05-17 Moore UCSD Cancer Center, La J... More >>olla, California, 92093, United States|UCLA Division of Hematology Oncology, Los Angeles, California, 90095, United States|University of California, San Francisco, San Francisco, California, 94143-0324, United States|Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, 80012, United States|Yale University, New Haven, Connecticut, 06519, United States|Georgetown University IRB, Washington, District of Columbia, 20007, United States|Washington Hospital Center, Washington, District of Columbia, 20010, United States|Cancer Centers of Florida, PA, Orlando, Florida, 32806-1124, United States|H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, 33612-9416, United States|Winship Cancer Institute of Emory University, Atlanta, Georgia, 30322, United States|Augusta Oncology Associates, P.C., Augusta, Georgia, 30901, United States|Central Georgia Cancer Care, Macon, Georgia, 31201, United States|Cancer Care and Hematology Specialists of Chicagoland, Arlington Heights, Illinois, 60005, United States|Hematology Oncology Assoc. of IL Orchard Research LLC, Chicago, Illinois, 60611, United States|Rush University Medical Center, Chicago, Illinois, 60612, United States|Consultants in Blood Disorders and Cancer, Louisville, Kentucky, 40207, United States|St. Agnes - Medical Center, Baltimore, Maryland, 21229-5299, United States|Center for Cancer And Blood Disorders, Bethesda, Maryland, 20817, United States|Center for Cancer Research CAMC, Bethesda, Maryland, 20892, United States|Tufts Medical Center, Boston, Massachusetts, 02111, United States|Henry Ford Hospital, Detroit, Michigan, 48202, United States|Minnesota Oncology Hematology, PA, Burnsville, Minnesota, 55337, United States|St. Joseph Oncology, Inc, Saint Joseph, Missouri, 64507, United States|Arch Medical Services, Saint Louis, Missouri, 63141, United States|Nebraska Cancer Specialists, Omaha, Nebraska, 68114, United States|Hackensack University Medical Center, Hackensack, New Jersey, 07601, United States|Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, United States|Weill Cornell Medical College, New York, New York, 10021, United States|Columbia University Medical Center, New York, New York, 10032, United States|Taussig Cancer Center Cleveland Clinic Foundation, Cleveland, Ohio, 44195, United States|Northwest Cancer Specialists, P.C., Portland, Oregon, 97227, United States|Accelerated Community Oncology Research Network Inc ACORN, Memphis, Tennessee, 38138, United States|Mamie McFadden Ward Center, Beaumont, Texas, 77702-1449, United States|Methodist Charlton Cancer Center, Dallas, Texas, 75237, United States|UT Southwestern Medical Center Simmons Comprehensive Cancer Center, Dallas, Texas, 75390-8565, United States|El Paso Cancer Treatment Center, El Paso, Texas, 79915, United States|Texas Oncology, P.A.-Fort Worth, Fort Worth, Texas, 76104, United States|UT MD Anderson Cancer Center, Houston, Texas, 77030-4009, United States|Allison Cancer Center, Midland, Texas, 79701, United States|US Oncology, Plano, Texas, 75093, United States|HOAST, San Antonio, Texas, 78229, United States|University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229, United States|Tyler Cancer Center, Tyler, Texas, 75702, United States|Texas Oncology, PA, Waco, Texas, 76712, United States|Fred Hutchinson Cancer Research Center, Seattle, Washington, 98109-1024, United States|Mater Private Medical Centre - Haematology and Oncology Clinics of Australasia Research Centre, South Brisbane, Queensland, 4101, Australia|Peter MacCallum Cancer Centre, East Melbourne, 3002, Australia|St. Vincent Hospital, Fitzroy, 3065, Australia|Royal North Shore Hospital, St Leonards, 2065, Australia|University Hospital Brno, Brno, 625 00, Czechia|University Hospital Hradec Kralove, Hradec Kralove, 500 05, Czechia|University Hospital of Kralovske Vinohrady, Prague 10, 100 34, Czechia|Charles University General Hospital, Prague 2, 128 08, Czechia|Polyclinique Bordeaux Nord Aquitaine, Bordeaux, 33000, France|Hopital Henri Mondor, Créteil, 94010, France|Hopital Claude Huriez, Lille, 59037, France|CHU Nantes Hotel Dieu, Nantes, 44093, France|Hopital Saint-Louis, Paris, 75010, France|Service des Maladies du Sang, Pessac, 33604, France|Centre Hospitalier Lyon Sud, Pierre Bénite, 69495, France|Centre Eugene Marquis, Rennes, 35033, France|Centre Henri Becquerel, Rouen Cedex, 79038, France|Charite Universitatsmedizin Berlin campus Virchow Klinikum Centrum fur Tumormedizin, Berlin, 13353, Germany|Krankenhaus Nordwest, Frankfurt a.M., 60488, Germany|Georg-August-Universit?t G?ttingen, G?ttingen, 37075, Germany|Uniklinik Koln, K?ln, 50937, Germany|Klinikum der Universitat Munchen-Grosshadern, Muenchen, D-81377, Germany|Klinikum Nurnberg Nord, Nürnberg, D- 90419, Germany|UKT Universitaetsklinikum Tuebingen, Tuebingen, 72076, Germany|Klinika Hematologii Akademickie Centrum Kliniczne Akademii Medycznej w Gdansku, Gdansk, 80-952, Poland|Oddzial Kliniczny Kliniki Hematologii, Kraków, 31 501, Poland|Wojewodzki Szpital Specjalistczny im. Mikolaja Kopernika, Lodz, 93-510, Poland|Klinika Nowotworow Ukladu Chlonnego, Warszawa, 02 781, Poland|Hospital Universitario Vall D Hebron, Barcelona, 08035, Spain|Hospital de La Princesa, Madrid, 28006, Spain|Hospital Universitario La Paz, Madrid, 28046, Spain|Clinica Universitaria de Navarra, Pamplona, 31008, Spain|Hospital Universitario de Salamanca, Salamanca, 37003, Spain|Hospital Marques de Valdecilla, Santandar, 39008, Spain|Lund University Hosptial, Lund, 22185, Sweden|Akademiska Sjukhuset, Uppsala, 75185, Sweden|Dnipropetrovsk State Medical Academy, Dnipropetrovsk, 49102, Ukraine|National Cancer Institute Department Of Conservative Methods Of Treatment, Kyiv, 03022, Ukraine|R.E.Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv, 03115, Ukraine|Institute of Blood Pathology and Transfusion Medicine of the AMS of Ukraine, Lviv, 79044, Ukraine|Royal Free Hospital, London Hampstead, NW3 2QG, United Kingdom|Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1A 7BE, United Kingdom|Guy's and St. Thomas' Hospital, London, SE1 9RT, United Kingdom|Catherine Lewis Centre - Hematology Department, London, W12 0HS, United Kingdom|Somers Cancer Research Building, Southampton, SO16 6YD, United Kingdom Less <<
NCT01324323 - Completed - -
NCT01979276 Multiple Myeloma Phase 1 Phase 2 Terminated(this study was term... More >>inated due to losing financial support, and enrollment challenges) Less << - United States, New York ... More >> Weill Cornell Medical College New York, New York, United States, 10065 Less <<
NCT03141203 Peripheral T Cell Lymphoma Phase 1 Phase 2 Recruiting February 2021 United Kingdom ... More >> Queen Elizabeth Hospital Recruiting Birmingham, United Kingdom Principal Investigator: Ram Malladi ?? ?? ?? St James's University Hospital Recruiting Leeds, United Kingdom Principal Investigator: Rod Johnson ?? ?? ?? Leicester Royal Infirmary Recruiting Leicester, United Kingdom Principal Investigator: Simon Wagner ?? ?? ?? Clatterbridge Cancer Centre Recruiting Liverpool, United Kingdom Principal Investigator: Nagesh Kalakonda ?? ?? ?? Guy's Hospital Recruiting London, United Kingdom Principal Investigator: Paul Fields ?? ?? ?? St Bartholomew's Hospital Recruiting London, United Kingdom Principal Investigator: Jeff Davies ?? ?? ?? University College London Hospitals Recruiting London, United Kingdom Principal Investigator: Kate Cwynarski ?? ?? ?? Christie Hospital Recruiting Manchester, United Kingdom Principal Investigator: Kim Linton ?? ?? ?? Nottingham University Hospitals Recruiting Nottingham, United Kingdom Principal Investigator: Chris Fox ?? ?? ?? Churchill Hospital Recruiting Oxford, United Kingdom Principal Investigator: Graham Collins ?? ?? ?? Derriford Hospital Recruiting Plymouth, United Kingdom Principal Investigator: David Lewis ?? ?? ?? Southampton General Hospital Recruiting Southampton, United Kingdom Principal Investigator: Andrew Davies ?? ?? ?? The Royal Marsden NHS Foundation Trust Recruiting Sutton, United Kingdom, SM2 5PT Principal Investigator: Dima El-Sharkawi Less <<
NCT01324323 Hematologic Malignancy ... More >> Malignant Lymphoma Less << Phase 1 Completed - United States, Florida ... More >> Florida Cancer Specialists Sarasota, Florida, United States, 34232 United States, Tennessee Sarah Canon Research Institute Nashville, Tennessee, United States, 37203 United Kingdom Sarah Cannon Research UK London, United Kingdom, W1G6AD Less <<
NCT01938833 - Terminated(Closed by Sponsor) - -
NCT02203578 Graft Versus Host Disease Not Applicable Terminated(slow accrual) - United States, New Jersey ... More >> Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey, United States, 08903 Less <<
NCT01938833 HER2-negative Breast Cancer ... More >> Inflammatory Breast Cancer Male Breast Cancer Recurrent Breast Cancer Stage IV Breast Cancer Less << Phase 1 Phase 2 Terminated(Closed by Sponsor) - United States, Pennsylvania ... More >> Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 Less <<
NCT02850016 Human Immunodeficiency Virus (... More >>HIV) Less << Phase 2 Recruiting December 2019 United States, New York ... More >> The Rockefeller University Recruiting New York, New York, United States, 10065 Contact: Katelyn Bastert ?? 800-782-2737 ?? rucares@rockefeller.edu ?? Principal Investigator: Marina Caskey, MD ?? ?? ?? Denmark Aarhus University Hospital Recruiting Aarhus, Denmark Contact: Ole Sogaard, MD, PhD ?? +45 7845 2842 ?? olesoega@rm.dk ?? Principal Investigator: Ole Sogaard, MD, PhD ?? ?? ?? Germany University of Cologne Recruiting Cologne, Germany, 50937 Contact: Gisela Kremer, RN ?? +41-221-478-3324 ?? gisela.kremer@uk-koeln.de ?? Principal Investigator: Gerd Kaetkenheuer, MD Less <<
NCT01353664 Lymphoma|Cancer PHASE2 COMPLETED 2012-09-05 Florida Cancer Specialists, Sa... More >>rasota, Florida, 34232, United States|Sarah Cannon Research Institute, Nashville, Tennessee, 37203, United States|Sarah Cannon Research UK, London, W1G6AD, United Kingdom Less <<
NCT02512497 Cutaneous T-cell Lymphoma ... More >> T-Prolymphocytic Leukemia T-Large Granulocytic Leukemia T-Lymphoblastic Leukemia/Lymphoma Peripheral T-Cell Lymphoma Less << Phase 1 Recruiting October 2019 United States, Ohio ... More >> The Ohio State University Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Rachel Conley ?? ?? Rachel.Conley@osumc.edu ?? Principal Investigator: Jonathan Brammer, MD Less <<
NCT01979276 - Terminated(this study was term... More >>inated due to losing financial support, and enrollment challenges) Less << - -
NCT01353664 Lymphoma|Cancer PHASE2 COMPLETED 2012-09-05 Florida Cancer Specialists, Sa... More >>rasota, Florida, 34232, United States|Sarah Cannon Research Institute, Nashville, Tennessee, 37203, United States|Sarah Cannon Research UK, London, W1G6AD, United Kingdom Less <<
NCT02203578 - Terminated(slow accrual) - -
NCT01324310 Hematologic Malignancy ... More >> Malignant Lymphoma Less << Phase 1 Completed - United States, Florida ... More >> Florida Cancer Specialists Sarasota, Florida, United States, 34232 United States, Tennessee Sarah Cannon Research Institute Nashville, Tennessee, United States, 37203 United Kingdom Sarah Cannon Research UK London, United Kingdom, W1G6AD Less <<
NCT01324310 - Completed - -
NCT01822886 Peripheral T-cell Lymphoma Phase 2 Completed - Italy ... More >> A.O. SS. Antonio e Biagio e C. Arrigo Alessandria, Italy, 15121 Istituto di Ematologia ed Oncologia Medica A. Seragnoli Policlinico S. Orsola Bologna, Italy, 40138 Fondazione IRCCS Istituto Nazionale dei Tumori Milano, Italy, 20133 A.O. Universitaria Citta' Della Salute E Della Scienza Di Torino Torino, Italy, 10126 Less <<
NCT01913119 Histologically Proven Extranod... More >>al NKTcell Lymphoma Less << EARLY_PHASE1 COMPLETED 2025-07-13 National Cancer Center, Goyang... More >>-si, Gyeonggi-do, 410-769, Korea, Republic of|Korea Cancer Center Hospital, Nowon-gu, Seoul, 139-709, Korea, Republic of|Severance Hospital, Seodaemun-gu, Seoul, 120-752, Korea, Republic of|Asan Medical Center, Songpa-gu, Seoul, 138-736, Korea, Republic of Less <<
NCT01537744 Solid Tumors ... More >>Virally Mediated Cancers and Liposarcoma Less << Phase 1 Completed - United States, Maryland ... More >> Sidney Kimmel Cancer Center @ Johns Hopkins Baltimore, Maryland, United States, 21231 Less <<
NCT01638533 Glioma Lympho... More >>ma Metastatic Malignant Solid Neoplasm Neuroendocrine Neoplasm Recurrent Adult Soft Tissue Sarcoma Recurrent Bladder Carcinoma Recurrent Breast Carcinoma Recurrent Chronic Lymphocytic Leukemia Recurrent Colorectal Carcinoma Recurrent Head and Neck Carcinoma Recurrent Lung Carcinoma Recurrent Malignant Solid Neoplasm Recurrent Melanoma Recurrent Pancreatic Carcinoma Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Recurrent Prostate Carcinoma Recurrent Renal Cell Carcinoma Recurrent Thyroid Gland Carcinoma Refractory Chronic Lymphocytic Leukemia Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma Stage III Breast Cancer AJCC v7 Stage III Colorectal Cancer AJCC v7 Stage III Cutaneous Melanoma AJCC v7 Stage III Lung Cancer AJCC v7 Stage III Pancreatic Cancer AJCC v6 and v7 Stage III Prostate Cancer AJCC v7 Stage III Renal Cell Cancer AJCC v7 Stage III Soft Tissue Sarcoma AJCC v7 Stage IIIA Breast Cancer AJCC v7 Stage IIIA Colorectal Cancer AJCC v7 Stage IIIA Cutaneous Melanoma AJCC v7 Stage IIIB Breast Cancer AJCC v7 Stage IIIB Colorectal Cancer AJCC v7 Stage IIIB Cutaneous Melanoma AJCC v7 Stage IIIC Breast Cancer AJCC v7 Stage IIIC Colorectal Cancer AJCC v7 Stage IIIC Cutaneous Melanoma AJCC v7 Stage IV Breast Cancer AJCC v6 and v7 Stage IV Colorectal Cancer AJCC v7 Stage IV Cutaneous Melanoma AJCC v6 and v7 Stage IV Lung Cancer AJCC v7 Stage IV Pancreatic Cancer AJCC v6 and v7 Stage IV Prostate Cancer AJCC v7 Stage IV Renal Cell Cancer AJCC v7 Stage IV Soft Tissue Sarcoma AJCC v7 Stage IVA Colorectal Cancer AJCC v7 Stage IVB Colorectal Cancer AJCC v7 Unresectable Solid Neoplasm Less << Phase 1 Recruiting - United States, California ... More >> City of Hope Comprehensive Cancer Center Suspended Duarte, California, United States, 91010 University of California Davis Comprehensive Cancer Center Suspended Sacramento, California, United States, 95817 City of Hope South Pasadena Recruiting South Pasadena, California, United States, 91030 Contact: Stephen C. Koehler ?? 626-396-2900 ?? skoehler@cohmg.com ?? Principal Investigator: Stephen C. Koehler ?? ?? ?? United States, Georgia Emory University Hospital/Winship Cancer Institute Suspended Atlanta, Georgia, United States, 30322 United States, Illinois University of Chicago Comprehensive Cancer Center Active, not recruiting Chicago, Illinois, United States, 60637 United States, Maryland Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting Baltimore, Maryland, United States, 21287 Contact: Roisin M. Connolly ?? 410-955-8804 ?? jhcccro@jhmi.edu ?? Principal Investigator: Roisin M. Connolly ?? ?? ?? National Cancer Institute Developmental Therapeutics Clinic Suspended Bethesda, Maryland, United States, 20892 National Institutes of Health Clinical Center Active, not recruiting Bethesda, Maryland, United States, 20892 United States, Michigan Wayne State University/Karmanos Cancer Institute Suspended Detroit, Michigan, United States, 48201 United States, Minnesota Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Paul Haluska ?? 507-284-2511 ?? haluska.paul@mayo.edu ?? Principal Investigator: Paul Haluska ?? ?? ?? United States, Ohio Case Western Reserve University Active, not recruiting Cleveland, Ohio, United States, 44106 United States, Pennsylvania Penn State Milton S Hershey Medical Center Active, not recruiting Hershey, Pennsylvania, United States, 17033-0850 Thomas Jefferson University Hospital Active, not recruiting Philadelphia, Pennsylvania, United States, 19107 United States, Wisconsin University of Wisconsin Hospital and Clinics Recruiting Madison, Wisconsin, United States, 53792 Contact: Roisin M. Connolly ?? 410-614-9217 ?? rconnol2@jhmi.edu ?? Principal Investigator: Roisin M. Connolly ?? ?? ?? Canada, Ontario University Health Network-Princess Margaret Hospital Recruiting Toronto, Ontario, Canada, M5G 2M9 Contact: Lillian L. Siu ?? 416-946-4501 ?? clinical.trials@uhn.on.ca ?? Principal Investigator: Lillian L. Siu Less <<
NCT03278782 Lymphoid Haematopoietic ... More >> Malignant Neoplasms Cutaneous T-Cell Lymphoma Refractory Cutaneous T-cell Lymphoma Less << Phase 1 Phase 2 Recruiting November 2020 United States, Texas ... More >> University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Clinical Research Operations ?? ?? spiyer@mdanderson.org Less <<
NCT03547700 Lymphoma, T-Cell, Peripheral Phase 1 Phase 2 Recruiting July 2021 United States, Michigan ... More >> University of Michigan Comprehensive Cancer Center Recruiting Ann Arbor, Michigan, United States, 48109 Contact: Ryan Wilcox, M.D. ?? 734-615-1482 ?? rwilcox@med.umich.edu ?? Contact: Sumana Devata ?? 734-615-7813 ?? sdevata@med.umich.edu Less <<
NCT02296398 Cutaneous T-cell Lymphoma COMPLETED 2025-08-15 Northwestern University Dermat... More >>ology Department, Chicago, Illinois, 60611, United States Less <<
NCT03355768 Lymphoma, T-Cell, Peripheral Phase 3 Not yet recruiting January 2020 United States, New York ... More >> Center for Lymphoid Malignancies at CUMC Not yet recruiting New York, New York, United States, 10019 Contact: Michelle Malanga, MPA ?? 212-326-5731 ?? mm4629@cumc.columbia.edu Less <<
NCT01738594 Recurrent Cutaneous T-cell Non... More >>-Hodgkin Lymphoma Recurrent Mycosis Fungoides/Sezary Syndrome Stage I Cutaneous T-cell Non-Hodgkin Lymphoma Stage IA Mycosis Fungoides/Sezary Syndrome Stage IB Mycosis Fungoides/Sezary Syndrome Stage II Cutaneous T-cell Non-Hodgkin Lymphoma Stage IIA Mycosis Fungoides/Sezary Syndrome Stage IIB Mycosis Fungoides/Sezary Syndrome Stage III Cutaneous T-cell Non-Hodgkin Lymphoma Stage IIIA Mycosis Fungoides/Sezary Syndrome Stage IIIB Mycosis Fungoides/Sezary Syndrome Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma Stage IVA Mycosis Fungoides/Sezary Syndrome Stage IVB Mycosis Fungoides/Sezary Syndrome Less << Phase 1 Active, not recruiting January 2020 United States, Illinois ... More >> Northwestern University Chicago, Illinois, United States, 60611 Less <<
NCT03770000 T Cell Lymphoma Phase 1 Phase 2 Not yet recruiting November 2020 United States, Texas ... More >> The University of Texas MD Anderson Cancer Center, Not yet recruiting Houston, Texas, United States, 77030 Contact: Swaminathan P Iyer, MD ?? ?? ?? The University of Texas MD Anderson Cancer Center, Not yet recruiting Houston, Texas, United States, 77030 Contact: Auris Huen, MD Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.85mL

0.37mL

0.18mL

9.25mL

1.85mL

0.92mL

18.49mL

3.70mL

1.85mL

References

 

Historical Records

Categories