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Chemical Structure| 1251006-64-0 Chemical Structure| 1251006-64-0
Chemical Structure| 1251006-64-0

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CAS No.: 1251006-64-0

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Product Details of [ 1251006-64-0 ]

CAS No. :1251006-64-0
Formula : C13H24N2O2
M.W : 240.34
SMILES Code : O=C(N1CC(C2CCNCC2)C1)OC(C)(C)C
MDL No. :MFCD14581437
InChI Key :NVJNOFWSEGNPKX-UHFFFAOYSA-N
Pubchem ID :56963412

Safety of [ 1251006-64-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 1251006-64-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1251006-64-0 ]

[ 1251006-64-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 14190-59-1 ]
  • [ 1251006-64-0 ]
  • [ 1373356-63-8 ]
YieldReaction ConditionsOperation in experiment
3.8 g To a stirring solution of compound 1g (14.3 mmol, 3.44 g) and <strong>[14190-59-1]thiazole-2-carboxylic acid</strong> 1 h (15.7 mmol, 2.03 g) in 50 mL of CH2Cl2 was added Et3N (42.9 mmol, 5.98 mL). After 20 min at 20° C., HATU (17.2 mmol, 6.53 g) was added and the mixture was stirred at 20° C. for 5 h. Water was added to the mixture and the organic layer was separated, dried over MgSO4, and concentrated. The residue was purified using flash column chromatography (silica gel, 30-70percent EtOAc/heptane) to give 3.8 g (75percent yield) of compound 11. MS m/z 374.2 (M+Na+), 296.1 (M+H-C4H8), 252.1 (M+H-C5H8O2).
 

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