Structure of Rivastigmine
CAS No.: 123441-03-2
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Rivastigmine is a acetylcholinesterase inhibitor with IC50 value of 5.5 μM for cholinesterase, used for the treatment of mild to moderate Alzheimer's disease and Parkinson's disease.
Synonyms: S-Rivastigmine; SDZ-ENA 713; Exelon
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Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 123441-03-2 |
Formula : | C14H22N2O2 |
M.W : | 250.34 |
SMILES Code : | O=C(OC1=CC=CC([C@@H](N(C)C)C)=C1)N(CC)C |
Synonyms : |
S-Rivastigmine; SDZ-ENA 713; Exelon
|
MDL No. : | MFCD00871496 |
InChI Key : | XSVMFMHYUFZWBK-NSHDSACASA-N |
Pubchem ID : | 77991 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Target |
|
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02860338 | - | Completed | - | - | |
NCT01401582 | Dementia | Not Applicable | Active, not recruiting | March 2018 | Germany ... More >> Institute for Community Medicine Greifswald, Mecklenburg- Western Pommerania, Germany, 17489 Less << |
NCT00291421 | - | Completed | - | - | |
NCT02623764 | - | Active, not recruiting | November 2019 | - | |
NCT01401582 | - | Active, not recruiting | - | - | |
NCT01852110 | Alzheimer's Disease | Phase 2 | Terminated(Stage 1 interim ana... More >>lysis of efficacy met the criteria for early trial termination (futility). The trial was terminated at Stage 1; did not proceed to Stage 2.) Less << | - | - |
NCT02374567 | Dementia Depr... More >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Less << | Phase 3 | Terminated | - | Germany ... More >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigsh?he Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Less << |
NCT00348140 | Alzheimer's Disease | Phase 3 | Completed | - | - |
NCT00880412 | Alzheimer's Disease | Phase 2 | Completed | - | France ... More >> H?pital Privé Les Magnolias Ballainvilliers, France, 91160 Cabinet Médical Bergerac, France, 24100 Fleyriat Hospital Bourg en Bresse, France, 01012 Cabinet Médical Dijon, France, 21000 Charles Foix Hospital Ivry sur Seine, France, 94026 Cabinet Médical La Seyne sur Mer, France, 83500 Roger Salengro Hospital Lille, France, 59037 Dupuytren Hospital Limoges, France, 87042 Clinique Léopold Bellan Magnanville, France, 78200 Cabinet Médical Montpellier, France, 34070 Cabinet Médical 2 Montpellier, France, 34080 CHU Nantes H?pital Laennec Nantes, France, 44093 Cabinet Médical 2 Nice, France, 06000 Cabinet Médical Nice, France, 06000 CHU Cochin Broca Paris, France, 75013 Cabinet Médical Rambouillet, France, 78120 CHU Rennes Rennes, France, 35033 Cabinet Médical Rodez, France, 12000 Cabinet Médical Rueil Malmaison, France, 92500 Cabinet Médical Saint Brieuc, France, 22000 Cabinet Médical Toulon, France, 83000 Purpan-Casselardit Hospital - University of Toulouse Toulouse, France, 31059 Less << |
NCT01852110 | - | Terminated(Stage 1 interim ana... More >>lysis of efficacy met the criteria for early trial termination (futility). The trial was terminated at Stage 1; did not proceed to Stage 2.) Less << | - | - | |
NCT02670161 | Brain Tumors ... More >>Epilepsy Migraine Mild Cognitive Impairment Concussion Multiple Sclerosis Neuropathy Parkinson's Restless Legs Syndrome Stroke Less << | Phase 4 | Enrolling by invitation | April 2020 | - |
NCT00348140 | - | Completed | - | - | |
NCT01696591 | - | Unknown | September 2013 | Korea, Republic of ... More >> Samsung Medical Center Recruiting Seoul, Korea, Republic of, 135-710 Contact: Duk L. Na, MD, PhD ?? +82-2-3410-3594 ?? dukna@naver.com Less << | |
NCT00105105 | Alzheimer's Disease | Phase 2 | Terminated | - | United States, Arizona ... More >> Pivotal Research Center Mesa, Arizona, United States, 85210 Pivotal Research Center Peoria, Arizona, United States, 85381 United States, California ATP Clinical Trials Fountain Valley, California, United States, 92708 UCI Irvine Medical Center Orange, California, United States, 92868 California Neuroscience Research Medical Group, Inc. Sherman Oaks, California, United States, 91403 AVI Clinical Research Torrance, California, United States, 90505 United States, Florida Baumel-Eisner Neuromed Inst Boca Raton, Florida, United States, 33486 Baumel-Eisner Neuromed Inst Ft. Lauderdale, Florida, United States, 33321 Clinical Physiology Associates Ft. Myers, Florida, United States, 33916 Baumel-Eisner Neuromed Inst Miami Beach, Florida, United States, 33154 Stedman Clinical Trials Tampa, Florida, United States, 33613 Johnnie B. Byrd, Sr. Alzheimer's Center & Research Inst Tampa, Florida, United States, 33647 United States, New Jersey Memory Enhancement Center Long Branch, New Jersey, United States, 07740 United States, New York Eastside Medical Research New York, New York, United States, 10021 United States, Ohio Neuro Center of Ohio Toledo, Ohio, United States, 43623 United States, Oklahoma Pahl Pharmaceutical Research, LLC Oklahoma City, Oklahoma, United States, 73118 Clinical Pharmaceutical Trials, Inc. Tulsa, Oklahoma, United States, 74104 United States, Pennsylvania Clinical Trials Research Services Pittsburgh, Pennsylvania, United States, 15206 United States, Texas Grayline Clinical Drug Trials Wichita Falls, Texas, United States, 76309 United States, Virginia International Clinical Research Associates Richmond, Virginia, United States, 23229 International Clinical Research Associates Virginia Beach, Virginia, United States, 23452 Less << |
NCT03565809 | - | Enrolling by invitation | December 2018 | France ... More >> University Hospital Toulouse, France, 31000 Less << | |
NCT00051909 | Alzheimer's Disease | Phase 2 | Completed | - | United States, California ... More >> Beverly Hills, California, United States Fresno, California, United States United States, Florida Boca Raton, Florida, United States Fort Lauderdale, Florida, United States Miami Beach, Florida, United States United States, Massachusetts Boston, Massachusetts, United States United States, Oklahoma Oklahoma City, Oklahoma, United States Tulsa, Oklahoma, United States United States, Texas Wichita Falls, Texas, United States Less << |
NCT00018278 | Alzheimer Disease | Phase 4 | Completed | - | United States, California ... More >> Department of Veterans Affairs San Diego, California, United States, 92161 Less << |
NCT02438202 | Alzheimer's Disease | Not Applicable | Not yet recruiting | January 2021 | - |
NCT01951118 | Alzheimer Disease ... More >> Mild Cognitive Impairment Delirium, Dementia, Amnestic, Cognitive Disorders Less << | Phase 4 | Active, not recruiting | May 2019 | United States, New York ... More >> New York State Psychiatric Institute New York, New York, United States, 10032 Less << |
NCT01023425 | Alzheimer's Disease ... More >> Dementia Less << | Not Applicable | Completed | - | Korea, Republic of ... More >> Samsung Medical Center Seoul, Korea, Republic of, 135-710 Less << |
NCT03025334 | Parkinson Disease ... More >> Mild Cognitive Impairment Less << | Not Applicable | Recruiting | December 2020 | Canada, Manitoba ... More >> University of Manitoba Recruiting Winnipeg, Manitoba, Canada, R3E 0J9 Contact: Ji Hyun Ko, PhD ?? 204-318-2566 ?? ji.ko@umanitoba.ca Less << |
NCT01554475 | - | Completed | - | Norway ... More >> Kl?ver?sen Bod?, Norway, N-8076 Less << | |
NCT01409564 | - | Completed | - | - | |
NCT00393432 | - | Completed | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << | |
NCT01626391 | - | Terminated(This study has been... More >> terminated for administrative reasons only.) Less << | - | - | |
NCT01626391 | Alzheimer's Disease | Phase 2 | Terminated(This study has been... More >> terminated for administrative reasons only.) Less << | - | Germany ... More >> Achim, Germany Berlin, Germany Leipzig, Germany München, Germany United Kingdom Birmingham, United Kingdom Bradford, United Kingdom Crowborough, United Kingdom Duston, United Kingdom Oxford, United Kingdom Sheffield, United Kingdom St Leonards on Sea, United Kingdom Staffordshire, United Kingdom Less << |
NCT00223691 | Autonomic Failure ... More >> Orthostatic Hypotension Less << | Phase 1 | Completed | - | United States, Tennessee ... More >> Vanderbilt University Nashville, Tennessee, United States, 37232 Less << |
NCT01409564 | Alzheimer's Dementia | Phase 4 | Completed | - | Korea, Republic of ... More >> SMG-SNU Boramae Medical Center Seoul, Korea, Republic of, 156-707 Less << |
NCT02007291 | - | Completed | - | - | |
NCT01872598 | Alzheimer Disease | Phase 3 | Active, not recruiting | October 2019 | Spain ... More >> Hospital Universitario Ramón y Cajal Madrid, Spain, 28034 Less << |
NCT01677754 | Alzheimer's Disease | Phase 2 | Completed | - | - |
NCT02007291 | - | Completed | - | - | |
NCT02187276 | - | Completed | - | - | |
NCT00766363 | Alzheimer's Disease ... More >> Central Nervous System Diseases Less << | Phase 1 | Completed | - | United States, California ... More >> Pacific Research Network, Inc. San Diego, California, United States, 92103 United States, Florida MD Clinical Hallandale Beach, Florida, United States, 33009 United States, New Jersey Comprehensive Clinical Research Berlin, New Jersey, United States, 08009 Global Medical Institutes, LLC Princeton, New Jersey, United States, 08540 Less << |
NCT00102284 | Healthy | Phase 4 | Terminated | - | Germany ... More >> Dept. of Neurology, University Hospital Muenster Muenster, Nordrhein-Westfalen, Germany, 48129 Less << |
NCT03250741 | Alzheimer Disease | Phase 2 | Recruiting | June 2018 | Italy ... More >> Santa Lucia Foundation Recruiting Rome, Italy, 00179 Contact: Sonia Bonnì Less << |
NCT00551161 | Alzheimer Disease | Phase 4 | Completed | - | United States, New York ... More >> The Litwin-Zucker Research Center Manhasset, New York, United States, 11030 Less << |
NCT00551161 | - | Completed | - | - | |
NCT03454646 | Alzheimer Disease ... More >> Cholinesterase Inhibitors Less << | Phase 4 | Not yet recruiting | September 15, 2021 | France ... More >> CHU d'Amiens Centre Mémoire Ressources Recherche Not yet recruiting Amiens, France, 80054 Contact: Agnès DEVENDEVILLE ?? 03.22.66.82.40 ?? devendeville.agnes@chu-amiens.fr ?? CHU d'Angers Centre Mémoire Ressources Recherche Angers, France, 49933 CHU de Bastia Centre Mémoire Ressources Recherche Not yet recruiting Bastia, France, 20604 Contact: Georges RETTALI ?? 04.95.59.18.32 ?? georges.retali@ch-bastia.fr ?? CHU de Besan?on Centre Mémoire Ressources Recherche Besan?on, France, 25030 CHU de Bordeaux - Service de Neurologie - Centre Mémoire Ressources Recherche - Not yet recruiting Bordeaux, France, 33076 Contact: Jean-Fran?ois DARTIGUES ?? 0557820116 ?? jean-fran?ois.dartigues@u-bordeaux.fr ?? CHRU Cavale Blanche Service de Gériatrie Brest, France, 29200 Service de Neuropsychologie H?pital Neurologique Pierre Wertheimer Not yet recruiting Bron, France, 69677 Contact: Hélène MOLLION ?? 04.72.35.71.79 ?? helene.mollion@chu-lyon.fr ?? CHU C?te de Nacre Service de neurologie et CMRR Caen, France, 14033 CHU de Clermont Ferrand Centre Mémoire Ressources Recherche Clermont-Ferrand, France, 63000 H?pital Pasteur Service de Neurologie Colmar, France, 68000 CHU de Dijon- CMRR Not yet recruiting Dijon, France, 21679 Contact: Yannick BEJOT ?? 03.80.29.58.03 ?? yannick.bejot@chu-dijon.fr ?? Chu de Grenoble CMRR, Neurologie Not yet recruiting Grenoble, France, 38043 Contact: Olivier MOREAUD ?? 04 76 76 57 90 ?? omoreaud@chu-grenoble.fr ?? H?pital Roger Salengro CMRR Lille, France, 59037 CHU Limoges Service de neurologie et CMRR Not yet recruiting Limoges, France, 87000 Contact: Leslie CARTZ-PIVER ?? 05.55.43.12.15 ?? Lcp.coglim@gmail.com ?? AP-HM Marseille, France CHU Montpellier H?pital Gui de Chauliac CMRR Not yet recruiting Montpellier, France, 34295 Contact: Audrey GABOREAU DE LOUSTAL ?? 04.67.33.60.29 ?? a-gabelle@chu-montpellier.fr ?? CHU de Nantes Clinique Neurologique H?pital GR Laennec Not yet recruiting Nantes, France, 44093 Contact: Claire BOUTOLEAU ?? 02.40.16.54.22 ?? claire.boutoleaubretonniere@chu-nantes.fr ?? Institut Claude Pompidou Centre Mémoire de Ressources et de Recherche Not yet recruiting Nice, France, 06100 Contact: Renaud David ?? 04.92.03.47.70 ?? claire.paquet@inserm.fr ?? APHP H?pital Broca Not yet recruiting Paris, France, 75013 Contact: Olivier HANON ?? 01.44.08.35.03 ?? olivier.hanon@brc.aphp.fr ?? H?pital Universitaire de la Pitié Salpêtrière Pavillon Fran?ois Lhermitte Not yet recruiting Paris, France, 75013 Contact: Stéphane EPELBAUM ?? 01.42.16.75.22 ?? stephane.epelbaum@psl.aphp.fr ?? APHP Groupe Hospitalier Saint Louis Lariboisière Fernand Widal CMRR Not yet recruiting Paris, France, 75475 Contact: Claire PAQUET ?? 01.40.05.49.54 ?? claire.paquet@inserm.fr ?? CHU La Milétrie P?le de Gériatrie Not yet recruiting Poitiers, France, 86021 Contact: Marc PACCALIN ?? 05.49.44.44.27 ?? m.paccalin@chu-poitiers.fr ?? CHU Reims H?pital Maison Blanche Court Séjour Gériatrique Not yet recruiting Reims, France, 51092 Contact: Jean-Luc NOVELLA ?? 03.26.78.44.10 ?? jl.novella@chu-reims.fr ?? CHU de Rennes - H?pital Pontchaillou / Service de Neurologie Not yet recruiting Rennes, France, 35033 Contact: Serge BELLIARD ?? 02.99.87.30.26 ?? serge.belliard@chu-rennes.fr ?? CHU de Rouen H?pital Charles Nicolle Service Neurologie Not yet recruiting Rouen, France, 76031 Contact: David Wallon ?? 06.08.97.29.59 ?? david.wallon@chu-rouen.fr ?? Chu de Saint-Etienne, CMRR Not yet recruiting Saint-étienne, France, 42055 Contact: Isabelle ROUCH ?? 04.77.12.73.98 ?? isabelle.rouch@chu-st-etienne.fr ?? Chu de Strasbourg H?pital Ka Robertsau P?le de Gériatrie - CMRR Not yet recruiting Strasbourg, France, 67200 Contact: Frédéric BLANC ?? 03.88.12.86.38 ?? frederic.blanc@chru-strasbourg.fr ?? Centre de Recherche Clinique du Gérontop?le Cité de la Santé Toulouse, France CHRU de Bretonneau Unité de gérontopsychiatrie Not yet recruiting Tours, France, 37000 Contact: Thomas DESMIDT ?? 06.68.07.97.06 ?? t.desmidt@chu-tours.fr ?? CHU Nancy Service de Gériatrie-CMRR Not yet recruiting Vandoeuvre les nancy, France, 54511 Contact: Thérèse RIVASSEAU JONVAUX ?? 03.83.15.35.71 ?? t.jonveaux@chu-nancy.fr ?? Hospice Civil de Lyon H?pital des Charpennes Not yet recruiting Villeurbanne, France, 69100 Contact: Pierre KROLAK SALMON ?? 04.72.43.20.50 ?? pierre.krolak-salmon@chu-lyon.fr Less << |
NCT01362686 | Dementia Alzh... More >>eimer's Disease Less << | Not Applicable | Terminated(Low study accrual c... More >>aused the study to be ended early.) Less << | - | United States, Indiana ... More >> Touchpoint Fishers, Indiana, United States, 46037 Methodist Center for Geriatric Medicine Indianapolis, Indiana, United States, 46202 University Clinical Neurology Indianapolis, Indiana, United States, 46202 Wishard Health Services Indianapolis, Indiana, United States, 46202 St. Vincent Center for Healthy Aging Indianapolis, Indiana, United States, 46260 Less << |
NCT00104442 | Alzheimer's Disease | PHASE4 | COMPLETED | 2025-04-06 | Novartis Pharmaceuticals, East... More >> Hanover, New Jersey, 07936, United States Less << |
NCT01696123 | Alzheimer Disease | Phase 2 | Completed | - | Iran, Islamic Republic of ... More >> Loghman Hospital Tehran, Iran, Islamic Republic of, 1315693446 Less << |
NCT00766363 | - | Completed | - | - | |
NCT00102856 | Healthy | Phase 4 | Suspended | - | Germany ... More >> Dept. of Neurology, University Hospital Muenster Muenster, Nordrhein-Westfalen, Germany, 48129 Less << |
NCT01362686 | - | Terminated(Low study accrual c... More >>aused the study to be ended early.) Less << | - | - | |
NCT00000174 | Alzheimer Disease|Cognition Di... More >>sorders Less << | PHASE3 | COMPLETED | - | Medici Research Centers, Peori... More >>a, Arizona, 85381, United States|University of California, Irvine, Orange, California, 92868, United States|University of Colorado Health Sciences Center, Denver, Colorado, 80220, United States|Neuromedical Research Institute (Offices in Ft. Lauderdale, Miami Beach and Boca Raton), Ft. Lauderdale, Florida, 33321, United States|Miami Research Associates, Miami, Florida, 33176, United States|Center for Clinical Trials and Research, Venice, Florida, 34285, United States|Indiana University Alzheimer's Center, Indianapolis, Indiana, 46202, United States|St. Louis University, St. Louis, Missouri, 63104, United States|Alzheimer's Research Corporation, Lakewood, New Jersey, 08701, United States|NYU Medical Center, New York, New York, 10016, United States|Duke University Medical Center, Durham, North Carolina, 27710, United States|Pahl Brain Associates, P.C., Oklahoma City, Oklahoma, 73118, United States|Clinical Studies, Ltd., Philadelphia, Philadelphia, Pennsylvania, 19106, United States|St. Paul Medical Center, Dallas, Texas, 75235, United States|University of Washington, Seattle, Seattle, Washington, 98108, United States Less << |
NCT01340885 | Parkinson's Disease | Phase 4 | Unknown | January 2013 | United States, Oregon ... More >> Oregon Health & Science University Recruiting Portland, Oregon, United States, 97239 Less << |
NCT01487317 | Delirium | Phase 3 | Completed | - | France ... More >> Pitié Salpetriere Hospital Paris, France, 75013 Less << |
NCT01944436 | - | Completed | - | Canada, Ontario ... More >> Sunnybrook Health Sciences Centre Toronto, Ontario, Canada, M4N3M5 Less << | |
NCT01348282 | Neurocognitive Disturbance ... More >> HIV Infection Less << | Phase 4 | Completed | - | Spain ... More >> Fundació LLuita contra la SIDA Badalona, Barcelona, Spain, 08916 Less << |
NCT00219232 | Alzheimer's Disease | Phase 3 | Completed | - | - |
NCT02035982 | Alzheimer's Disease ... More >> Dementia Less << | Phase 3 | Completed | - | Canada, Ontario ... More >> North York General Hospital Toronto, Ontario, Canada, M2K1E1 Sunnybrook Health Sciences Centre Toronto, Ontario, Canada, M4N 3M5 Less << |
NCT01519271 | - | Completed | - | - | |
NCT01856738 | Parkinson's Disease | Phase 4 | Terminated(enrollment to slow,... More >> insufficient funds) Less << | - | Netherlands ... More >> Academic Medical Center Amsterdam, Netherlands, 1100 DD University Medical Center Groningen Groningen, Netherlands, 9700 RB Atrium Medical Center Heerlen, Netherlands, 6401 CX University Medical Center St Radboud Nijmegen, Netherlands, 6500 HB Less << |
NCT00767091 | Parkinson's Disease ... More >> Apathy no Dementia Less << | Phase 3 | Completed | - | France ... More >> Devos Lille, Nord, France, 59037 Less << |
NCT00099242 | Alzheimer's Disease ... More >> Dementia, Alzheimer Type Less << | Phase 3 | Completed | - | - |
NCT01519271 | Parkinson's Disease ... More >> Mild Cognitive Impairment Less << | Phase 4 | Completed | - | United States, Pennsylvania ... More >> University of Pennsylvania, Ralston House Philadelphia, Pennsylvania, United States, 19104 Less << |
NCT00234637 | Alzheimer's Disease | Phase 4 | Completed | - | France ... More >> Département de Gérontologie Clinique Limoges, Cedex, France, 87042 Less << |
NCT01948791 | Alzheimer's Disease | Phase 4 | Completed | - | China ... More >> Novartis Investigative Site Beijing, China, 100053 Less << |
NCT01948791 | - | Completed | - | - | |
NCT00506415 | Alzheimer Disease | Phase 3 | Completed | - | - |
NCT00158210 | Substance-Related Disorders | PHASE1 | COMPLETED | 2025-03-07 | University of California - Los... More >> Angeles, Los Angeles, California, 90024, United States Less << |
NCT00599287 | Delirium | Phase 3 | Terminated(Inclusion rate too ... More >>low due to a lack of eligible patients and difficulties obtaining informed consent.) Less << | - | Netherlands ... More >> University Medical Center Utrecht, Netherlands, 3508 GA Less << |
NCT00506415 | - | Completed | - | - | |
NCT03659435 | Bioequivalence | Phase 1 | Recruiting | November 30, 2018 | Germany ... More >> SocraTec R&D GmbH, Clinical Pharmacology Unit Recruiting Erfurt, Thüringen, Germany, 99084 Contact: Cornelius Koch, MD ?? +49-361-60205 ext 67 ?? cornelius.koch@socratec-pharma.de Less << |
NCT01614886 | Alzheimer's Disease | Phase 3 | Completed | - | - |
NCT01614886 | - | Completed | - | - | |
NCT00257868 | Delirium | Phase 3 | Completed | - | Switzerland ... More >> University Hospital Basel Basel, Switzerland, 4031 Less << |
NCT00099216 | Vascular Dementia | PHASE3 | COMPLETED | 2025-11-05 | Irvine, California, 92618, Uni... More >>ted States|San Francisco, California, 94109, United States|Boynton Beach, Florida, 33426, United States|Miami Beach, Florida, 33140, United States|Port Charlotte, Florida, United States|Indianapolis, Indiana, 46202, United States|Des Moines, Iowa, 50314, United States|St. Louis, Missouri, United States|Albuquerque, New Mexico, United States|New York, New York, 10003, United States|Portland, Oregon, 97223, United States|Allentown, Pennsylvania, 18103, United States|Greensburg, Pennsylvania, 15601, United States|Charleston, South Carolina, 29406, United States|Austin, Texas, 78756, United States|Houston, Texas, 77030, United States|Bennington, Vermont, 05201, United States|Graz, Austria|Linz, Austria|Wien, Austria|Edmonton, Alberta, Canada|Ottawa, Ontario, Canada|Toronto, Ontario, Canada|Montreal, Quebec, Canada|Amiens, France|Bordeaux, France|Lille Cedex, France|Marseille, France|Montpellier Cedex, France|Toulouse, France|Tours Cedex, France|Bautzen, Germany|Berlin, Germany|Bochum, Germany|Chemnitz, Germany|Eisenhuttenstadt, Germany|Erlangen, Germany|Freiburg, Germany|Luedenscheid, Germany|Osnabrueck, Germany|Ancona, Italy|Brescia, Italy|Firenze, Italy|Perugia, Italy|Reggio Emilia, Italy|Roma, Italy|Vicenza, Italy|Moscow, Russian Federation|Saint-Petersburg, Russian Federation|Barakaldo, Spain|Barcelona, Spain|Madrid, Spain|Pamplona, Spain|Saint Cugat del Valles, Spain|Basel, Switzerland|Lausanne, Switzerland|Newcastle Upon Tyne, Newcastle, United Kingdom|Swindon, Wiltshire, United Kingdom|Bristol, United Kingdom|Clydebank, United Kingdom|East Sussex, United Kingdom|Southampton, United Kingdom|St Annes, United Kingdom Less << |
NCT00627848 | Alzheimer' Disease | Not Applicable | Completed | - | Finland ... More >> Kuopio University Hospital Kuopio, Finland, 70211 Less << |
NCT00522015 | Progressive Supranuclear Palsy... More >> Dementia Less << | Phase 2 | Unknown | - | Germany ... More >> University of Tuebingen Recruiting Tuebingen, Baden Wuerttemberg, Germany, 72076 Contact: Daniela Berg, Doctor ?? +49 7071 29 80438 ?? daniela.berg@uni-tuebingen.de Less << |
NCT00549601 | Alzheimer's Disease | Phase 4 | Completed | - | Spain ... More >> Novartis Investigative Site Barcelona, Spain Less << |
NCT00669344 | Cognitive Impairment | Phase 4 | Completed | - | Singapore ... More >> Singapore General Hospital Singapore, Singapore, 169608 Less << |
NCT00549601 | - | Completed | - | - | |
NCT01602198 | - | Terminated(Study revised to us... More >>e a different study medication and patient population.) Less << | - | - | |
NCT01602198 | Mild Cognitive Disorder ... More >> Mild Cognitive Impairment Less << | Not Applicable | Terminated(Study revised to us... More >>e a different study medication and patient population.) Less << | - | United States, Ohio ... More >> Cleveland Clinic Cleveland, Ohio, United States, 44195 Less << |
NCT00134953 | Cognitive Symptoms | PHASE3 | TERMINATED | 2025-05-04 | - |
NCT03573050 | Bioequivalence | Phase 1 | Completed | - | Germany ... More >> SocraTec R&D GmbH, Clinical Pharmacology Unit Erfurt, Thüringen, Germany, 99084 Less << |
NCT00305903 | Alzheimer's Disease | Phase 4 | Completed | - | United States, New Jersey ... More >> Manchester, New Jersey, United States, 08759 Less << |
NCT01047579 | Alzheimer's Disease | Phase 4 | Completed | - | Israel ... More >> Novartis Investigative Site Ashkelon, Israel Novartis Investigational Site Haifa, Israel Novartis Investigative Site Holon, Israel Novartis Investigative Site Ramat Gan, Israel Novartis Investigative Site Tel Aviv, Israel Less << |
NCT00130338 | Vascular Dementia | PHASE3 | COMPLETED | 2025-05-06 | - |
NCT00219245 | Traumatic Brain Injury With Pe... More >>rsistent Cognitive Deficits Less << | PHASE4 | COMPLETED | 2025-01-05 | - |
NCT01399125 | - | Completed | - | - | |
NCT00731224 | Alzheimer's Disease | Phase 4 | Completed | - | - |
NCT00171795 | Traumatic Brain Injury | PHASE3 | COMPLETED | 2025-05-05 | - |
NCT00704301 | Delirium | Phase 4 | Terminated(The study is premat... More >>urely terminated due to a safety issue) Less << | - | Netherlands ... More >> Medical Center Leeuwarden Leeuwarden, Friesland, Netherlands, 8901 BR Gelre Hospitals; lukas site Apeldoorn, Gelderland, Netherlands, 7300 DS Medical Center Alkmaar Alkmaar, Noord-Holland, Netherlands, 1800 AM Erasmus Medical Center Rotterdam, Zuid-Holland, Netherlands, 3000 CA University Medical Center Utrecht Utrecht, Netherlands, 3508 GA Diakonessenhuis Utrecht, Netherlands, 3582 KE Less << |
NCT00948766 | Alzheimer's Disease | Phase 4 | Completed | - | - |
NCT00948766 | - | Completed | - | - | |
NCT00423085 | - | Completed | - | - | |
NCT00881205 | Multiple Sclerosis ... More >> Cognitive Impairment Less << | Phase 4 | Terminated(Termination of stud... More >>y due to low enrollment) Less << | - | - |
NCT00423085 | Alzheimer's Disease | Phase 3 | Completed | - | Japan ... More >> Novartis Investigative Site Hokkaido region, Hokkaido, Japan Less << |
NCT00881205 | - | Terminated(Termination of stud... More >>y due to low enrollment) Less << | - | - | |
NCT02839642 | Progressive Supranuclear Palsy... More >> (PSP) Less << | Phase 3 | Recruiting | November 2019 | France ... More >> Service de Neurologie et Pathologie du Mouvement H?pital de La Timone Recruiting Marseille Cedex 5, France, 13385 Contact: Alexandre EUSEBIO, Dr ?? 04.91.38.43.33 ext +33 ?? alexandre.eusebio@ap-hm.fr Less << |
NCT00988117 | Parkinsons Disease With Dement... More >>ia Parkinsons Disease With Mild to Moderate Memory and/or Thinking Problems Less << | Phase 4 | Completed | - | United States, California ... More >> UCalifornia SF San Francisco, California, United States, 94117 Less << |
NCT01399125 | Alzheimer's Disease | Phase 3 | Completed | - | China, Fujian ... More >> Novartis Investigative Site Fuzhou, Fujian, China China, Hubei Novartis Investigative Site Wuhan, Hubei, China, 430022 Novartis Investigative Site Wuhan, Hubei, China, 430030 China, Jiangsu Novartis Investigative Site Nanjing, Jiangsu, China, 210029 Novartis Investigative Site Suzhou, Jiangsu, China, 215004 China, Jilin Novartis Investigative Site Changchun, Jilin, China, 130021 China, Shanghai Novartis Investigative Site Shanghai, Shanghai, China, 200080 China, Shanxi Novartis Investigative Site Xi'an, Shanxi, China, 710032 China, Sichuan Novartis Investigative Site Chengdu, Sichuan, China, 610041 China, Zhejiang Novartis Investigative Site Hangzhou, Zhejiang, China, 310009 China Novartis Investigative Site Beijing, China, 100028 Novartis Investigative Site Beijing, China, 100730 Novartis Investigative Site Shanghai, China, 200003 Novartis Investigative Site Shanghai, China, 200025 Novartis Investigative Site Shanghai, China, 200040 Novartis Investigative Site Shanghai, China, 200127 Less << |
NCT01025466 | Alzheimer's Disease | Phase 4 | Completed | - | Korea, Republic of ... More >> Soonchunhyang University Hospital Bucheon, Korea, Republic of, 420-767 The Catholic University of Korea Hospital Bucheon, Korea, Republic of Donga University Hospital Busan, Korea, Republic of, 602-715 Changwon Fatima Hospital Changwon, Korea, Republic of, 641-560 Keimyung University Dongsan Medical Center Daegu, Korea, Republic of, 700-712 Daejun Eulji University Hopistal Daejun, Korea, Republic of, 302-799 Dongguk University Medical Center Goyang, Korea, Republic of, 41-773 Myongji Hospital Goyang, Korea, Republic of, 412-270 Chonnam National University Hospital Gwangju, Korea, Republic of, 501-757 Wonkwang University Hospital Iksan, Korea, Republic of, 570-180 Inha Univeristy Hospital Incheon, Korea, Republic of, 400-711 Gachon University Gil Medical Center Incheon, Korea, Republic of, 405-760 Pusan National University Hospital Pusan, Korea, Republic of, 602-739 Maryknoll Hospital Pusan, Korea, Republic of Bobath Memorial Hospital Seongnam, Korea, Republic of Kyughee University Medical Center Seoul, Korea, Republic of, 130-702 Kangdong Sacred Heart Hospital Seoul, Korea, Republic of, 134-701 Sungkyunkwan University, Samsung Seoul Hospital Seoul, Korea, Republic of, 135-710 Konkuk University Hospital Seoul, Korea, Republic of, 143-729 Hallym University Hospital Seoul, Korea, Republic of, 150-719 Ewha Womans University Hospital Seoul, Korea, Republic of, 158-710 Asan Medical Center Seoul, Korea, Republic of, 431-060 Seoul Eulji Hospital Seoul, Korea, Republic of Seoul Medical Center Seoul, Korea, Republic of Seoul National University Boramae Hospital Seoul, Korea, Republic of Ajou University Hospital Suwon, Korea, Republic of Less << |
NCT00988117 | - | Completed | - | - | |
NCT00748007 | Down Syndrome | COMPLETED | 2025-12-09 | Department of Medical Genetics... More >>, National Taiwan University Hospital, Taipei, 100, Taiwan Less << | |
NCT00428389 | Alzheimer's Disease | Phase 3 | Completed | - | - |
NCT00428389 | - | Completed | - | - | |
NCT00561392 | Alzheimer's Disease | Phase 4 | Completed | - | Germany ... More >> Novartis Investigative Site Munich, Germany Less << |
NCT01670526 | Traumatic Brain Injury ... More >> Cognitive Impairment Less << | Phase 3 | Completed | - | United States, California ... More >> VA San Diego Healthcare System, San Diego, CA San Diego, California, United States, 92161 United States, Florida Miami VA Healthcare System, Miami, FL Miami, Florida, United States, 33125 James A. Haley Veterans' Hospital, Tampa, FL Tampa, Florida, United States, 33612 United States, Illinois Edward Hines Jr. VA Hospital, Hines, IL Hines, Illinois, United States, 60141-5000 United States, Nebraska Lincoln Community-Based Outpatient Clinic, Lincoln, NE Lincoln, Nebraska, United States, 68510 United States, South Carolina Ralph H. Johnson VA Medical Center, Charleston, SC Charleston, South Carolina, United States, 29401-5799 United States, Texas Michael E. DeBakey VA Medical Center, Houston, TX Houston, Texas, United States, 77030 United States, Utah VA Salt Lake City Health Care System, Salt Lake City, UT Salt Lake City, Utah, United States, 84148 Less << |
NCT00561392 | - | Completed | - | - | |
NCT01380288 | Alzheimer's Disease | Not Applicable | Completed | - | Korea, Republic of ... More >> Holy Family Hospital, The Catholic Univerisy of Korea, School of Medicine Bucheon, Korea, Republic of Busan National University Hospital Busan, Korea, Republic of Busan Paik Hospital, Inje University College of Medicine Busan, Korea, Republic of Changwon Fatima Hospital Changwon, Korea, Republic of Daegu Fatima Hospital Daegu, Korea, Republic of Keimyung University School of Medicine Daegu, Korea, Republic of Kyungpook National University School of Medicine Daegu, Korea, Republic of Myongji Hospital, Kwandong University College of Medicine Goyang, Korea, Republic of Dongguk University International Hospital Ilsan, Korea, Republic of National Health Insurance Corporation Ilsan Hospital Ilsan, Korea, Republic of Inha University College of Medicine Incheon, Korea, Republic of Gyeongsang National University College of Medicine Jinju, Korea, Republic of Chonnam National University, Medical School Kwangju, Korea, Republic of Seoul National Unviersity College of Medicine, Clinical neuroscience center, Seoul National Unviersity Bundang Hospital Seongnam, Korea, Republic of The Catholic Univerisy of Korea, School of Medicine Seoul, Korea, Republic of Pusan National University Yangsan Hospital Yangsan, Korea, Republic of Less << |
NCT01585272 | - | Completed | - | - | |
NCT01670526 | - | Completed | - | - | |
NCT01529619 | Alzheimer's Disease | Phase 4 | Completed | - | Japan ... More >> Novartis Investigative Site Nagoya-city, Aichi, Japan, 467-8602 Novartis Investigative Site Fukuoka-city, Fukuoka, Japan, 814-0180 Novartis Investigative Site Miyoshi-city, Hiroshima, Japan, 728-0013 Novartis Investigative Site Ohtake, Hiroshima, Japan, 739-0696 Novartis Investigative Site Kita-gun, Kagawa, Japan, 761-0793 Novartis Investigative Site Kamakura-city, Kanagawa, Japan, 247-8533 Novartis Investigative Site Kawasaki-city, Kanagawa, Japan, 216-8511 Novartis Investigative Site Yokohama, Kanagawa, Japan, 241-0811 Novartis Investigative Site Koshi-city, Kumamoto, Japan, 861-1116 Novartis Investigative Site Kyoto-city, Kyoto, Japan, 600-8558 Novartis Investigative Site Kyoto, Japan, 606-0851 Less << |
NCT00622713 | Alzheimer's Disease | Phase 4 | Completed | - | France ... More >> Novartis Investigative Site Rueil-Malmaison, France Less << |
NCT00623103 | - | Completed | - | - | |
NCT00622713 | - | Completed | - | - | |
NCT00623103 | Parkinson's Disease Dementia | Phase 3 | Completed | - | - |
NCT01084135 | Down Syndrome | Phase 1 Phase 2 | Completed | - | United States, Maryland ... More >> Kennedy Krieger Institute Baltimore, Maryland, United States, 21205 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 Less << |
NCT01585272 | Alzheimer's Dementia | Phase 4 | Completed | - | Taiwan ... More >> Novartis Investigative Site Taichung, Taiwan ROC, Taiwan Novartis Investigative Site Taipei, Taiwan, ROC, Taiwan, 112 Novartis Investigative Site Taichung, Taiwan, 40447 Novartis Investigative Site Taipei, Taiwan, 10002 Less << |
NCT00835159 | - | Completed | - | - | |
NCT01030692 | Cocaine Dependence ... More >> Cocaine Addiction Cocaine Abuse Substance Abuse Less << | Phase 1 | Completed | - | United States, Texas ... More >> Michael E. DeBakey Veterans Affairs Medical Center Houston, Texas, United States, 77030 Less << |
NCT01084135 | - | Completed | - | - | |
NCT01146041 | Healthy | PHASE1 | COMPLETED | 2025-04-04 | - |
NCT01146067 | Healthy | PHASE1 | COMPLETED | 2025-02-04 | - |
NCT01312363 | - | Completed | - | Korea, Republic of ... More >> Korea University Ansan Hospital Ansan, Gyeonggi-do, Korea, Republic of, 425-707 Myongji Hospital Goyang-si, Gyeonggi-do, Korea, Republic of, 412-270 Wonkwang University Sanbon Medical Center Gunpo-si, Gyeonggi-do, Korea, Republic of, 435-040 Hanyang University Guri Hospital Guri-si, Gyeonggi-do, Korea, Republic of, 471-701 Bobath Memorial Hospital Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-480 Yong-in Hyoja Geriatric Hospital Yongin-si, Gyeonggi-do, Korea, Republic of Dong-A University Hospital Busan, Korea, Republic of Pusan National University Hospital Busan, Korea, Republic of Hallym University Chunchon Hospital Chunchon, Korea, Republic of Konyang University Hospital Daejeon, Korea, Republic of Inha University Hospital Incheon, Korea, Republic of, 400-711 Jeju National University Hospital Jeju, Korea, Republic of, 690-756 Seoul St. Mary's Hospital Seoul, Korea, Republic of, 137-701 SungAe General Hospital Seoul, Korea, Republic of, 150-051 Chungang University Hospital Seoul, Korea, Republic of, 156-755 Ewha Womans University Hospital Seoul, Korea, Republic of Hanyang University Seoul Hospital Seoul, Korea, Republic of Kyung Hee University Medical Center Seoul, Korea, Republic of Sanggye Paik Hospital Seoul, Korea, Republic of Less << | |
NCT01183806 | Alzheimer Disease | Phase 3 | Completed | - | Brazil ... More >> Ferderal University of Bahia - DINEP Salvador, Bahia, Brazil, 40.110-170 Federal University of Bahia Salvador, Bahia, Brazil, 40110170 Less << |
NCT00835159 | Delirium Post... More >>operative Cognitive Dysfunction Less << | Phase 4 | Completed | - | United States, New York ... More >> NYU Langone Medical Center, Department of Anesthesiology 550 First Avenue, RR-603 New York, New York, United States, 10016 Less << |
NCT01073319 | Methamphetamine Dependence ... More >> Substance Abuse Methamphetamine Abuse Less << | Phase 1 | Completed | - | United States, Texas ... More >> Michael E. DeBakey VA Medical Center Houston, Texas, United States, 77030 Less << |
NCT02413554 | Delirium | Phase 4 | Completed | - | - |
NCT00624663 | Rivastigmine Toxicity | COMPLETED | 2025-04-09 | Tel Aviv Sourasky Medical Cent... More >>er, Tel Aviv, Israel|Tasmc Clinical Research Center, Tel-Aviv, 64239, Israel Less << | |
NCT02989402 | Alzheimer's Disease | PHASE4 | COMPLETED | 2022-12-08 | Novartis Investigative Site, B... More >>angalore, Karnataka, 560 055, India|Novartis Investigative Site, Bangalore, Karnataka, 560052, India|Novartis Investigative Site, Banglaore, Karnataka, 560052, India|Novartis Investigative Site, Bengaluru, Karnataka, 560005, India|Novartis Investigative Site, Mumbai, Maharashtra, 400 053, India|Novartis Investigative Site, Hyderabad, Telangana, 500082, India|Novartis Investigative Site, Lucknow, Uttar Pradesh, 226003, India|Novartis Investigative Site, Kolkata, West Bengal, 700017, India|Novartis Investigative Site, Kolkata, West Bengal, 700054, India Less << |
NCT02703636 | Mild to Moderate Alzheimer's D... More >>isease Less << | Phase 4 | Completed | - | Japan ... More >> Novartis Investigative Site Fukuoka-city, Fukuoka, Japan, 814-001 Novartis Investigative Site Fukuoka-city, Fukuoka, Japan, 814-0180 Novartis Investigative Site Aizuwakamatsu, Fukushima, Japan, 965-8585 Novartis Investigative Site Tsukuba-city, Ibaraki, Japan, 305-8576 Novartis Investigative Site Kita-gun, Kagawa, Japan, 761-0793 Novartis Investigative Site Sagamihara-city, Kanagawa, Japan, 252-5188 Novartis Investigative Site Kochi-city, Kochi, Japan, 780-0842 Novartis Investigative Site Kurashiki-city, Okayama, Japan, 710-0826 Novartis Investigative Site Osaka-city, Osaka, Japan, 543-8555 Novartis Investigative Site Suita-city, Osaka, Japan, 565 0871 Novartis Investigative Site Kasukabe-city, Saitama, Japan, 344-0036 Novartis Investigative Site Koshigaya-city, Saitama, Japan, 343-0032 Novartis Investigative Site Fuji-city, Shizuoka, Japan Novartis Investigative Site Bunkyo-ku, Tokyo, Japan, 113-8431 Novartis Investigative Site Hachioji-city, Tokyo, Japan, 193-0944 Novartis Investigative Site Shinjuku-ku, Tokyo, Japan, 160-0023 Novartis Investigative Site Niigata, Japan Novartis Investigative Site Okayama, Japan, 710-0813 Novartis Investigative Site Tokyo, Japan, 168-8535 Less << |
NCT02063269 | Alzheimer's Disease | UNKNOWN | 2025-06-17 | Seoul Metropolitan Government ... More >>Seoul National University Boramae Medical Center, Seoul, 156-707, Korea, Republic of Less << | |
NCT02444637 | Alzheimer Disease|CVA (Cerebro... More >>vascular Accident) Less << | PHASE4 | COMPLETED | 2025-03-19 | National Neuroscience Institut... More >>e, Singapore, 308433, Singapore Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.99mL 0.80mL 0.40mL |
19.97mL 3.99mL 2.00mL |
39.95mL 7.99mL 3.99mL |
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Dissolving Methods |
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
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