成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 1226-42-2 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1226-42-2
Chemical Structure| 1226-42-2
Structure of 1226-42-2 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 1226-42-2 ]

Related Doc. of [ 1226-42-2 ]

Alternatived Products of [ 1226-42-2 ]
Product Citations

Product Details of [ 1226-42-2 ]

CAS No. :1226-42-2 MDL No. :MFCD00008405
Formula : C16H14O4 Boiling Point : -
Linear Structure Formula :CH3OC6H4C(O)C(O)C6H4OCH3 InChI Key :YNANGXWUZWWFKX-UHFFFAOYSA-N
M.W : 270.28 Pubchem ID :71043
Synonyms :
p-Anisil
Chemical Name :1,2-Bis(4-methoxyphenyl)ethane-1,2-dione

Calculated chemistry of [ 1226-42-2 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 20
Num. arom. heavy atoms : 12
Fraction Csp3 : 0.12
Num. rotatable bonds : 5
Num. H-bond acceptors : 4.0
Num. H-bond donors : 0.0
Molar Refractivity : 74.53
TPSA : 52.6 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : Yes
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : Yes
Log Kp (skin permeation) : -5.59 cm/s

Lipophilicity

Log Po/w (iLOGP) : 2.7
Log Po/w (XLOGP3) : 3.32
Log Po/w (WLOGP) : 2.77
Log Po/w (MLOGP) : 1.57
Log Po/w (SILICOS-IT) : 3.35
Consensus Log Po/w : 2.74

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -3.72
Solubility : 0.0513 mg/ml ; 0.00019 mol/l
Class : Soluble
Log S (Ali) : -4.1
Solubility : 0.0214 mg/ml ; 0.0000793 mol/l
Class : Moderately soluble
Log S (SILICOS-IT) : -5.07
Solubility : 0.00231 mg/ml ; 0.00000855 mol/l
Class : Moderately soluble

Medicinal Chemistry

PAINS : 1.0 alert
Brenk : 1.0 alert
Leadlikeness : 0.0
Synthetic accessibility : 1.68

Safety of [ 1226-42-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1226-42-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1226-42-2 ]

[ 1226-42-2 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 54523-47-6 ]
  • [ 1226-42-2 ]
  • [ 870249-44-8 ]
YieldReaction ConditionsOperation in experiment
90% With potassium hydroxide; In ethanol; at 70℃; for 3h;Inert atmosphere; (2) Intermediate product 2 (3.69 g, 10 mmol), 4,4'-dimethoxyphenol ester (Compound 3) (2.7 g, 10 mmol) and potassium hydroxide (0.168 g, 3 mmol) were added to the reaction flask, pumped three times, and solvent ethanol (30mL) was injected under nitrogen protection. The resulting mixture was refluxed at 70 C for three hours. After completion of the reaction, the reaction flask was cooled in an ice bath and precipitated to obtain the product. The product was washed with cold ethanol and dried to give red powder product 4 (compound 4). Yield 90%.
  • 2
  • [ 1226-42-2 ]
  • [ 84-16-2 ]
  • 3
  • [ 4506-66-5 ]
  • [ 1226-42-2 ]
  • [ 1227468-71-4 ]
  • 4
  • [ 7474-78-4 ]
  • [ 1226-42-2 ]
  • [ 1394971-68-6 ]
YieldReaction ConditionsOperation in experiment
80% In ethanol; water;Reflux; Step 2. 2,3-Bis-(4-methoxyphenyl)quinoxaline-6-sulfonic acid A solution of 1,2-bis(4-methoxyphenyl)ethane-1,2-dione (400 mg, 1.48 mmol, 1.00 equiv) and <strong>[7474-78-4]3,4-diaminobenzenesulfonic acid</strong> (278 mg, 1.48 mmol, 1.00 equiv) in ethanol/water (1:1, 20 mL) was stirred overnight at reflux in an oil bath. The resulting mixture was concentrated in vacuo, resulting in 500 mg (80percent) of 2,3-bis-(4-methoxyphenyl)quinoxaline-6-sulfonic acid as a brown solid.
80% In ethanol; water;Reflux; A solution of 1,2-bis(4-methoxyphenyl)ethane-1,2-dione (400 mg, 1.48 mmol, 1.00 equiv) and <strong>[7474-78-4]3,4-diaminobenzenesulfonic acid</strong> (278 mg, 1.48 mmol, 1.00 equiv) in ethanol/water (10/10 mL) was stirred overnight at reflux in an oil bath. The resulting mixture was concentrated under vacuum, yielding 500 mg (80percent) of 2,3-bis(4-methoxyphenyl)quinoxaline-6-sulfonic acid as a brown solid.
  • 5
  • [ 105-13-5 ]
  • [ 4903-09-7 ]
  • [ 1226-42-2 ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records
; ;