Alternatived Products of [ 112-05-0 ]
Product Details of [ 112-05-0 ]
| CAS No. : | 112-05-0 |
MDL No. : | MFCD00004433 |
| Formula : |
C9H18O2
|
Boiling Point : |
- |
| Linear Structure Formula : | CH3(CH2)7COOH |
InChI Key : | FBUKVWPVBMHYJY-UHFFFAOYSA-N |
| M.W : |
158.24
|
Pubchem ID : | 8158 |
| Synonyms : |
Pelargonic acid;Pelargonic acid (n-Nonanoic acid, C9 );n-Nonanoic acid;112-05-0;C9:0 Fatty acid;Nonoic acid
|
Chemical Name : | Pelargonic Acid |
Application In Synthesis of [ 112-05-0 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 112-05-0 ]
- 1
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[ 112-80-1 ]
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[ 112-05-0 ]
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[ 3788-56-5 ]
- 2
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[ 124-38-9 ]
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[ 3386-35-4 ]
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[ 112-05-0 ]
- 3
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[ 112-05-0 ]
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[ 35661-60-0 ]
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Fmoc-L-Dab(Dde)-OH, DDE = 1-(4,4-dimethyl-2,6-dioxocylohexylidene)ethyl
[ No CAS ]
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[ 71989-35-0 ]
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[ 86123-10-6 ]
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[ 125238-99-5 ]
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[ 688316-86-1 ]
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C88H146N15O22Pol
[ No CAS ]
- 4
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[ 143-28-2 ]
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[ 112-05-0 ]
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[ 3788-56-5 ]
| Yield | Reaction Conditions | Operation in experiment |
|
|
Oleyl alcohol (100 ml) is dissolved in propanoic acid (200 ml) in a jacketed reactor equipped with a gas sparger and an overhead stirrer. The reaction mixture is cooled to 10C while stirring and an 03/air mixture is sparged through the reactor over the course of 100 minutes until all olefin has been consumed, making sure that the internal temperature does not exceed 15C. The peroxide value of the mixture is tested using iodometric titration and is calculated to be 450 mmol/L. (0192) [00056] This mixture is then pumped through a " OD tube packed with sand mixed with 5% by wt. V2O5 that is kept at 90C. The flow rate is established such that the residence time in the packed tube is less than 15 minutes. After the material has passed through the tube, another peroxide test is performed the peroxide value was calculated to be 40 mmol/L. (0193) [00057] This mixture is then collected, charged with 250 mg of V2O5, and is sparged with oxygen at between 70 and 80C for several hours until lH NMR shows no more aldehyde peak to be present. Finally, the propanoic acid solvent is removed via distillation, resulting in a mixture of nonanoic acid, 9-hydroxynonanoic acid, and corresponding esters. The NMR data for this mixture is provided in Figure 2. The resulting mixture from Example 5 (86 g) is charged with Amberlyst cationic resin beads (~2 g) and is distilled at reduced pressure 0.5-2 mbar and 100C for 4 hours. |
- 5
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[ 112-05-0 ]
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[ 3788-56-5 ]
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[ 75544-92-2 ]
| Yield | Reaction Conditions | Operation in experiment |
|
With 2,3,4,5,6-pentahydroxy-hexanal; cytochrome b5; glucose dehydrogenase from Bacillus megaterium; human cytochrome P450 monooxygenase; rat cytochrome P450 reductase; 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; NADPH; superoxide dismutase; catalase from bovine liver; In aq. phosphate buffer; dimethyl sulfoxide; at 30℃;pH 7.5;Enzymatic reaction; |
General procedure: Conversions of fatty acids 1-8 and fatty alcohols 9-12 were carried out in 50mM potassium phosphate buffer, pH 7.5 and a total reaction volume of 100muL. Reaction mixtures contained 0.25muM CYP4B1, 0.5muM CPR, 0.25muM cytochrome b5, 100 U mL-1 superoxide dismutase, 1000 UmL-1 catalase, 25 U mL-1 GDH, 20mM glucose, 25mugmL-1 DLPC, 200muM substrate (from a 10mM stock solution dissolved in DMSO) and 200muM NADPH. Samples were incubated at 30C for 90min; this reaction time was chosen as an almost complete substrate conversion (as achieved for C12 4 after 120min) was not desirable, so as to allow comparison of the conversion values for the individual substrates and also between the two CYP4B1 isoforms. |
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