Alternatived Products of [ 1104637-53-7 ]
Product Details of [ 1104637-53-7 ]
CAS No. : | 1104637-53-7 |
MDL No. : | MFCD11215242 |
Formula : |
C7H8BNO4
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | NHVZIRZCTRJEFP-UHFFFAOYSA-N |
M.W : |
180.95
|
Pubchem ID : | 71310651 |
Synonyms : |
|
Safety of [ 1104637-53-7 ]
Application In Synthesis of [ 1104637-53-7 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1104637-53-7 ]
- 1
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[ 40263-57-8 ]
-
[ 1104637-53-7 ]
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C12H11BN2O5
[ No CAS ]
- 2
-
[ 1104637-53-7 ]
-
[ 175278-00-9 ]
-
2-trifluoromethoxy-phenylethynylboronic acid MIDA ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
85% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 30℃; for 1h;Inert atmosphere; Sealed tube; |
General procedure: For example, synthesis of 1,2-diphenylethyne, 3a. To an oven-dried 5 mL microwave vessel was added Pd(PPh3)2Cl2 (3.5 mg, 0.005 mmol, 2 mol %) and CuI (1.9 mg, 0.01 mmol, 4 mol %). The vessel was then capped and purged with N2 before addition of Cyrene (0.5 mL, 0.5 M), Et3N (38 muL, 0.275 mmol, 1.1 equiv), iodobenzene (27.9 muL, 0.25 mmol, 1 equiv), and phenylacetylene (28.8 muL, 0.263 mmol, 1.05 equiv). The reaction mixture was heated to 30 C and maintained at this temperature with stirring for 1 h before the vessel was vented, and decapped. The solution was then diluted with EtOAc (10 mL), and washed with water (2× 20 mL) and brine (2 × 20 mL). The organics were then passed through a hydrophobic frit and concentrated under reduced pressure to give a yellow oil, which was purified by flash chromatography (silica gel, 0-5% Et2O in petroleum ether) to afford the title compound as a white solid (44.5 mg, quant.). |