成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 103438-88-6 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 103438-88-6
Chemical Structure| 103438-88-6
Structure of 103438-88-6 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 103438-88-6 ]

Related Doc. of [ 103438-88-6 ]

Alternatived Products of [ 103438-88-6 ]
Product Citations

Product Details of [ 103438-88-6 ]

CAS No. :103438-88-6 MDL No. :MFCD03411962
Formula : C8H7FO2 Boiling Point : No data available
Linear Structure Formula :- InChI Key :LIHCOUDNHILORI-UHFFFAOYSA-N
M.W : 154.13 Pubchem ID :3774463
Synonyms :

Safety of [ 103438-88-6 ]

Signal Word:Danger Class:
Precautionary Statements:P261-P264-P270-P271-P272-P280-P301+P312+P330-P302+P352-P304+P340+P312-P305+P351+P338+P310-P333+P313-P403+P233-P405-P501 UN#:
Hazard Statements:H302-H315-H317-H318-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 103438-88-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 103438-88-6 ]

[ 103438-88-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 103438-88-6 ]
  • [ 103438-86-4 ]
YieldReaction ConditionsOperation in experiment
28% With boron tribromide; In dichloromethane; at -78 - 0℃; for 3h; Example66; 4-(2-Fluoro-3-hydroxyphenyl)-N-(6-fluoro-lH-indazol-5-yl)-2- methyl-6-oxo-1, 4,5, 6-tetrahydro-3-pyridinecarboxamide;. Step 1;. 2-Fluoro-3-hydroxybenzaldehyde.; BBr3 (4 mL, 4 mmol, 1.0 M in heptane) was added dropwise to a solution of 2- fluoro-5- (methyloxy) benzaldehyde in CH2C12 at-78 C. The reaction mixture was stirred at-78 C for 1 hour, slowly warmed to 0 C and stirred for 2 hours. The reaction mixture was poured into water, extracted with EtOAc (3 x 10 mL). The extracts were combined, washed with water, brine, and dried (Na2SO4). The solvent was evaporated, and the residue was purified on silica gel, using 0-20% EtOAc-Hexaxie to give the desired product (158 mg, 28%) as a white solid. MS m/z 141 [M+H] +.
2% A. 2-Fluoro-3-hydroxybenzaldehyde.; 2-Fluoro-3-methoxybenzaldehyde(1.0 g, 6.49 mmol) was dissolved in CH2Cl2 and cooled to -78 C. Boron tribromide (IM in CH2Cl2, 16.22 mL, 16.22 mmol) was added slowly and the reaction was allowed to warm to rt overnight. An ice/water mixture was added to the resulting slurry and stirred for 30 min. The layers were separated and the organic layer was washed with NaHCO3 (sat.) and 2N NaOH. The aqueous layer was acidified with cone. HCl and extracted with CH2Cl2. The organic layer was dried and concentrated to afford the title compound (0.190 g, 1.36 mmol, 21% yield).
With boron tribromide; In dichloromethane; at -78 - -20℃; for 4h; To a solution of the compound 12-1 (1 .4 g, 9 mmol) in 50 mL DCM was added dropwise BBr3 (4M in DCM, 3.6 mL, 13.5 mmol) at -78 C. After the addition, the reaction was stirred at -20 C for 4 hours. After slow addition of ice/water, the layers were separated, the organic layer was washed with water and brine, dried over Na2S04 and evaporated to dryness. The residue was used to next step without further purification.
With boron tribromide; In dichloromethane; at -70 - -20℃; for 4h; To a solution of the compound 12-1 (1.4 g, 9 mmol) in 50 mL DCM was added dropwise BBr3 (4M in DCM, 3.6 mL, 13.5 mmol) at -78 C. After the addition, the reaction was stirred at -20 C. for 4 hours. After slow addition of ice/water, the layers were separated, the organic layer was washed with water and brine, dried over Na2SO4 and evaporated to dryness. The residue was used to next step without further purification.
With boron tribromide; In dichloromethane; at -78 - -20℃; for 4h; To a solution of the compound 12-1 (1.4 g, 9 mmol) in 50 mL DCM was added dropwise BBr3 (4M in DCM, 3.6 mL, 13.5 mmol) at -78 C. After the addition, the reaction was stirred at -20 C. for 4 hours. After slow addition of ice/water, the layers were separated, the organic layer was washed with water and brine, dried over Na2SO4 and evaporated to dryness. The residue was used to next step without further purification
With boron tribromide; In dichloromethane; at -70 - -20℃; for 4h; To a solution of the compound 12-1 (1.4 g, 9 mmol) in 50 mL DCM was added dropwise BBr3 (4M in DCM, 3.6 mL, 13.5 mmol) at -78 C. After the addition, the reaction was stirred at -20 C. for 4 hours. After slow addition of ice/water, the layers were separated, the organic layer was washed with water and brine, dried over Na2SO4 and evaporated to dryness. The residue was used to next step without further purification.

Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 103438-88-6 ]

Fluorinated Building Blocks

Chemical Structure| 870837-66-4

[ 870837-66-4 ]

2,4-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 177034-25-2

[ 177034-25-2 ]

2,4-Difluoro-5-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 886499-89-4

[ 886499-89-4 ]

2,4,6-Trifluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 467457-62-1

[ 467457-62-1 ]

2-Fluoro-3-phenoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 149949-30-4

[ 149949-30-4 ]

2,6-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

Aryls

Chemical Structure| 870837-66-4

[ 870837-66-4 ]

2,4-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 177034-25-2

[ 177034-25-2 ]

2,4-Difluoro-5-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 886499-89-4

[ 886499-89-4 ]

2,4,6-Trifluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 467457-62-1

[ 467457-62-1 ]

2-Fluoro-3-phenoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 149949-30-4

[ 149949-30-4 ]

2,6-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

Aldehydes

Chemical Structure| 870837-66-4

[ 870837-66-4 ]

2,4-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 177034-25-2

[ 177034-25-2 ]

2,4-Difluoro-5-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 886499-89-4

[ 886499-89-4 ]

2,4,6-Trifluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 467457-62-1

[ 467457-62-1 ]

2-Fluoro-3-phenoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 149949-30-4

[ 149949-30-4 ]

2,6-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

Ethers

Chemical Structure| 870837-66-4

[ 870837-66-4 ]

2,4-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 177034-25-2

[ 177034-25-2 ]

2,4-Difluoro-5-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 886499-89-4

[ 886499-89-4 ]

2,4,6-Trifluoro-3-methoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 467457-62-1

[ 467457-62-1 ]

2-Fluoro-3-phenoxybenzaldehyde

Similarity: 0.98

Chemical Structure| 149949-30-4

[ 149949-30-4 ]

2,6-Difluoro-3-methoxybenzaldehyde

Similarity: 0.98

; ;