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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 102518-79-6 Chemical Structure| 102518-79-6
Chemical Structure| 102518-79-6

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CAS No.: 102518-79-6

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Huperzine A is a naturally occurring sesquiterpene alkaloid AChE inhibitor.

Synonyms: Hup A; (-)-Selagine.; Selagine

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of (-)-Huperzine A

CAS No. :102518-79-6
Formula : C15H18N2O
M.W : 242.32
SMILES Code : O=C1C=CC([C@@](/C2=C/C)(N)CC(C)=C[C@@]2([H])C3)=C3N1
Synonyms :
Hup A; (-)-Selagine.; Selagine
MDL No. :MFCD01714949

Safety of (-)-Huperzine A

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H300-H310-H315-H319-H330-H335
Precautionary Statements:P260-P264-P280-P284-P301+P310-P302+P350
Class:6.1
UN#:1544
Packing Group:Ⅱ

Isoform Comparison

Biological Activity

Target

  • AChE

    AChE (G4 form), Ki:7 nM

  • GluR

    AChE (G4 form), Ki:7 nM

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01136551 Healthy|Bioavailability UNKNOWN 2025-04-11 Hadassah University Hospital, ... More >>Jerusalem, Israel Less <<
NCT01012830 Schizophrenia|Dementia PHASE4 UNKNOWN 2025-04-11 Veterans Affairs Nebraska West... More >>ern Iowa Health Care System, Omaha, Nebraska, 68105, United States Less <<
NCT00083590 Alzheimer Disease PHASE2 COMPLETED 2025-11-07 University of Alabama, Birming... More >>ham, Alabama, 35294, United States|Banner Alzheimer's Institute, Phoenix, Arizona, 85006, United States|University of California, Irvine, Irvine, California, 92697, United States|University of California, San Diego, Alzheimer's Disease Research Center, La Jolla, California, 92037, United States|University of Southern California, Los Angeles, California, 90033, United States|University of California, Davis, Sacramento, California, 95817, United States|Howard University School of Medicine, Washington, DC, District of Columbia, 20060, United States|Georgetown University Medical Center, Memory Disorders Program, Washington, District of Columbia, 20057, United States|MD Clinical, Fort Lauderdale, Florida, 33321, United States|Roskamp Institute Memory Clinic, Tampa, Florida, 33617, United States|University of South Florida, Suncoast Alzheimer's and Gerontology Center, Tampa, Florida, 33617, United States|Premiere Research Institute, West Palm Beach, Florida, 33407, United States|Emory University, Atlanta, Georgia, 30329, United States|Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, 60612, United States|ICPS Group, Boston, Massachusetts, 02131, United States|University of Nevada School of Medicine, Las Vegas, Nevada, 89102, United States|Alzheimer's Research Corporation, Manchester, New Jersey, 08759, United States|University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey, 08855, United States|Albany Medical Center, Albany, New York, 12208, United States|New York University Medical Center, New York, New York, 10016, United States|Mount Sinai School of Medicine, New York, New York, 10029, United States|Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, 10962, United States|University of Rochester Medical Center, Rochester, New York, 14620, United States|University of North Carolina, Chapel Hill, North Carolina, 27599, United States|Oregon Health and Science University, Portland, Oregon, 97201, United States|University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States|Medical University of South Carolina, North Charleston, South Carolina, 29406, United States|University of Texas Southwestern Medical Center, Dallas, Texas, 75390, United States|University of Vermont College of Medicine, Burlington, Vermont, 05401, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.13mL

0.83mL

0.41mL

20.63mL

4.13mL

2.06mL

41.27mL

8.25mL

4.13mL
Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

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