成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

  • <thead id="xkwbf"><sup id="xkwbf"></sup></thead>
    <thead id="xkwbf"></thead>
    <pre id="xkwbf"></pre>
    • <center id="xkwbf"><sub id="xkwbf"></sub></center>
    



    
	
    
		
		
		
    
		
		
    
	
    
	
	
    
    
    
    
	
    
	
    
		
	
    		

    

    
	Home
	Cart 0
	Sign in
	 

    

    















    
    
    
        
    
    
    
    
        
        
    
            
    
                
                    
    [ CAS No. 102-93-2 ] {[proInfo.proName]}
    
                
                
                 ,{[proInfo.pro_purity]}
            
    
            
            
    
            
    
                
    
                    
    
                        
    
                            Cat. No.: {[proInfo.prAm]}
                            
                        
    
                        
    
                            
                            
                            
                                
                            
                        
    
                        
    
                            
                            
    
                                Chemical Structure| 102-93-2
                                
                                    
    
                                        Chemical Structure| 102-93-2
                                    
    
                                    
                                Structure of 102-93-2
                                 * Storage: {[proInfo.prStorage]}
                            
    
                            
                            
    
                                
                                
                            
    
                            
                        
    
                    
    
                    
    
                        
                        
    Please Login or Create an Account to: See VIP prices and availability
    
                        
    
                            
                              Cart0
                            
                            Add to My Favorites
                            Add to My Favorites
                            Bulk Inquiry
                            Inquiry
                            Add To Cart
                        
     
                    
    
                
    
                
    
                
    
                    
    
                        
    Search after Editing
    
                        
     * Storage: {[proInfo.prStorage]}
    
                        
     * Shipping: {[proInfo.prShipping]}
    
                    
    
                    
                
    
                
            
    
            
    
                
    
                    
    Quality Control of [ 102-93-2 ]
    
                    
    
                        
    
                            
                        
    
                        
     
                        
                        
    
                            
    Related  Doc. of [ 102-93-2 ]
    
                            
                        
    
                    
    
                
    
                
            
    
            
    
        
    
        
        
    
            
    
                
                
    
                    
                    Alternatived Products of [ 102-93-2 ]
                    
    
                    
    
                
    
                
                
    
                    Product Citations
                
    
                
                
    
                    
    Product Citations 
    
                    
                    
    
                        
    
                            
                            
    
                            
    
                                
                                
                                    
                                    Anushree Mondal
                                    
                                    
                                    ; 
                                    
                                
                                    
                                     Pronay Roy
                                    
                                    
                                    ; 
                                    
                                
                                    
                                     Jaclyn Carrannatto
                                    
                                    
                                
                                    
                                    
                                
                                    
                                    
                                
                                    
                                    
                                
                                
                                    , et al.
                                
                                
                                
                                    
                                
                                
                                DOI: 
                                    
                                
                                
                                
                                PubMed ID: 
                                    
                                
                                
                            
    
                            
                            
    
                                
                                
    Abstract: The prenylated-flavin mononucleotide-dependent decarboxylases (also known as UbiD-like enzymes) are the most recently discovered family of decarboxylases. The modified flavin facilitates the decarboxylation of unsaturated carboxylic acids through a novel mechanism involving 1,3-dipolar cyclo-addition chemistry. UbiD-like enzymes have attracted considerable interest for biocatalysis applications due to their ability to catalyse (de)carboxylation reactions on a broad range of aromatic substrates at otherwise unreactive carbon centres. There are now ～35[thin space (1/6-em)]000 protein sequences annotated as hypothetical UbiD-like enzymes. Sequence similarity network analyses of the UbiD protein family suggests that there are likely dozens of distinct decarboxylase enzymes represented within this family. Furthermore, many of the enzymes so far characterized can decarboxylate a broad range of substrates. Here we describe a strategy to identify potential substrates of UbiD-like enzymes based on detecting enzyme-catalysed solvent deuterium exchange into potential substrates. Using ferulic acid decarboxylase (FDC) as a model system, we tested a diverse range of aromatic and heterocyclic molecules for their ability to undergo enzyme-catalysed H/D exchange in deuterated buffer. We found that FDC catalyses H/D exchange, albeit at generally very low levels, into a wide range of small, aromatic molecules that have little resemblance to its physiological substrate. In contrast, the sub-set of aromatic carboxylic acids that are substrates for FDC-catalysed decarboxylation is much smaller. We discuss the implications of these findings for screening uncharacterized UbiD-like enzymes for novel (de)carboxylase activity.
    
                            
    
                            
                            
                            
                            
    Purchased from AmBeed: 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     ; 
                                
                                     
                                
                                
                                
                                
                            
    
                            
                        
    
                        
                        
    
                            
                            
                        
    
                        
                        
    
                    
    
                    
                
    
                
                
                
    
                    
    Product Details of [ 102-93-2 ]
    
                    
    
                        
                            
                            
                            
                            
                        
                        
    
                            CAS No. :102-93-2
                            MDL No. :MFCD00025535
                        
    
                        
    
                            Formula :
                            
                            
                                C9H11NO
                            
                            Boiling Point :
                            -
                        
    
                        
    
                            Linear Structure Formula :-
                            InChI Key :VYIBCOSBNVFEIW-UHFFFAOYSA-N
                        
    
                        
    
                            M.W :
                            
                                
                                    149.19  
                                
                            
                            Pubchem ID :7625
                        
    
                        
    
                            Synonyms :
                            
                                
    
                                    
                                
    
                                		
                            
                            
                        
    
                        
                        
                    
    
                
    
                
                
                
    
                    
    Calculated chemistry of [ 102-93-2 ]      Expand+
    
                    
                    
    
                        
    
                            
    Physicochemical Properties
    
                            
                            
     
                                 
                                
                                    
    
                                        Num. heavy atoms :
                                        11
                                    
     
                                    
    
                                        Num. arom. heavy atoms :
                                        6
                                    
     
                                    
    
                                        Fraction Csp3 :
                                        0.22
                                    
     
                                    
    
                                        Num. rotatable bonds :
                                        3
                                    
    
                                    
    
                                        Num. H-bond acceptors :
                                        1.0
                                    
    
                                    
    
                                        Num. H-bond donors :
                                        1.0
                                    
    
                                    
    
                                        Molar Refractivity :
                                        43.93
                                    
    
                                    
    
                                        TPSA :
                                        43.09 ?2
                                    
    
                                    
                            
    
                        
    
                        
    
                            
    Pharmacokinetics
    
                            
     
                                
                                
                                    
    
                                        GI absorption :
                                        High
                                    
     
                                    
    
                                        BBB permeant :
                                        Yes
                                    
     
                                    
    
                                        P-gp substrate :
                                        No
                                    
    
                                    
    
                                        CYP1A2 inhibitor :
                                        Yes
                                    
    
                                    
    
                                        CYP2C19 inhibitor :
                                        No
                                    
    
                                    
    
                                        CYP2C9 inhibitor :
                                        No
                                    
    
                                    
    
                                        CYP2D6 inhibitor :
                                        No
                                    
    
                                    
    
                                        CYP3A4 inhibitor :
                                        No
                                    
    
                                    
    
                                        Log Kp (skin permeation) :
                                        -6.56 cm/s
                                    
    
                                    
                            
    
                        
    
                    
    
                    
    
                        
    
                            
    Lipophilicity
    
                            
     
                                
                                
                                    
    
                                        Log Po/w (iLOGP) :
                                        1.45
                                    
     
                                    
    
                                        Log Po/w (XLOGP3) :
                                        0.91
                                    
     
                                    
    
                                        Log Po/w (WLOGP) :
                                        1.1
                                    
    
                                    
    
                                        Log Po/w (MLOGP) :
                                        1.58
                                    
    
                                    
    
                                        Log Po/w (SILICOS-IT) :
                                        1.64
                                    
    
                                    
    
                                        Consensus Log Po/w :
                                        1.34
                                    
    
                                    
                            
    
                        
    
                        
    
                            
    Druglikeness
    
                            
     
                                
                                
                                    
    
                                        Lipinski :
                                        0.0
                                    
     
                                    
    
                                        Ghose :
                                        None
                                    
     
                                    
    
                                        Veber :
                                        0.0
                                    
    
                                    
    
                                        Egan :
                                        0.0
                                    
    
                                    
    
                                        Muegge :
                                        1.0
                                    
    
                                    
    
                                        Bioavailability Score :
                                        0.55
                                    
    
                                    
                            
    
                        
    
                    
    
                    
    
                        
    
                            
    Water Solubility
    
                            
     
                                 
                                
                                    
    
                                        Log S (ESOL) :
                                        -1.54
                                    
     
                                    
    
                                        Solubility :
                                        4.26 mg/ml ; 0.0286 mol/l
                                    
     
                                    
    Class :
                                        Very soluble
                                    
     
                                    
    
                                        Log S (Ali) :
                                        -1.4
                                    
     
                                    
    
                                        Solubility :
                                        5.93 mg/ml ; 0.0398 mol/l
                                    
    
                                    
    Class :
                                        Very soluble
                                    
    
                                    
    
                                        Log S (SILICOS-IT) :
                                        -2.78
                                    
    
                                    
    
                                        Solubility :
                                        0.249 mg/ml ; 0.00167 mol/l
                                    
    
                                    
    
                                        Class :
                                        Soluble
                                    
    
                                    
                            
    
                        
    
                        
    
                            
    Medicinal Chemistry
    
                            
     
                                
                                
                                    
    
                                        PAINS :
                                        0.0 alert
                                    
     
                                    
    
                                        Brenk :
                                        0.0 alert
                                    
    
                                    
    
                                        Leadlikeness :
                                        1.0
                                    
    
                                    
    
                                        Synthetic accessibility :
                                        1.0
                                    
    
                                    
                            
    
                        
    
                    
    
                
    
                
                
                
    
                    
    Safety of [ 102-93-2 ]
    
                    
    
                        
                            
                            
                            
                            
                         
                        
    
                            Signal Word:Warning
                            Class:N/A
                        
    
                        
    
                            Precautionary Statements:P261-P305+P351+P338
                            UN#:N/A
                        
    
                        
    
                            Hazard Statements:H302-H315-H319-H335
                            Packing Group:N/A
                        
    
                        
                            
    
                                GHS Pictogram:
                                
                                    
                                        
                                    
                                    
                                    
                            
    
                        
                    
    
                
    
                
                                
                
                
			    
                
                    
                
                
                
    
                    Recommend Products
                    
                
    
                
                
    
                    Same Skeleton Products
                    
                
    
                
                
                
                
                
                
                
    
                    
    Technical Information
    
                    
                
    
                 

                
                
    
                    Historical Records
                    
                
    
            
    
            
            
    
                
                
                
                
                
                
                
                    
    
                        
    Related Functional Groups of 
    [ 102-93-2 ]
    
                        
                            
                                
    Aryls
    
                                
                                    
    
                                        
    Chemical Structure| 86-86-2
    
                                        
    
                                            
    [ 86-86-2 ]
    
                                            
    1-Naphthaleneacetamide
    
                                            
     Similarity: 0.85
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 937-39-3
    
                                        
    
                                            
    [ 937-39-3 ]
    
                                            
    2-Phenylacetohydrazide
    
                                            
     Similarity: 0.78
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 34800-90-3
    
                                        
    
                                            
    [ 34800-90-3 ]
    
                                            
    2-(Naphthalen-1-yl)acetohydrazide
    
                                            
     Similarity: 0.74
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 88-96-0
    
                                        
    
                                            
    [ 88-96-0 ]
    
                                            
    Phthalamide
    
                                            
     Similarity: 0.74
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 104-53-0
    
                                        
    
                                            
    [ 104-53-0 ]
    
                                            
    3-Phenylpropanal
    
                                            
     Similarity: 0.73
    
                                        
    
                                    
    
                                
                            
                        
                            
                                
    Amides
    
                                
                                    
    
                                        
    Chemical Structure| 86-86-2
    
                                        
    
                                            
    [ 86-86-2 ]
    
                                            
    1-Naphthaleneacetamide
    
                                            
     Similarity: 0.85
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 937-39-3
    
                                        
    
                                            
    [ 937-39-3 ]
    
                                            
    2-Phenylacetohydrazide
    
                                            
     Similarity: 0.78
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 112-84-5
    
                                        
    
                                            
    [ 112-84-5 ]
    
                                            
    cis-13-Docosenamide
    
                                            
     Similarity: 0.77
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 34800-90-3
    
                                        
    
                                            
    [ 34800-90-3 ]
    
                                            
    2-(Naphthalen-1-yl)acetohydrazide
    
                                            
     Similarity: 0.74
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 88-96-0
    
                                        
    
                                            
    [ 88-96-0 ]
    
                                            
    Phthalamide
    
                                            
     Similarity: 0.74
    
                                        
    
                                    
    
                                
                            
                        
                            
                                
    Amines
    
                                
                                    
    
                                        
    Chemical Structure| 86-86-2
    
                                        
    
                                            
    [ 86-86-2 ]
    
                                            
    1-Naphthaleneacetamide
    
                                            
     Similarity: 0.85
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 937-39-3
    
                                        
    
                                            
    [ 937-39-3 ]
    
                                            
    2-Phenylacetohydrazide
    
                                            
     Similarity: 0.78
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 112-84-5
    
                                        
    
                                            
    [ 112-84-5 ]
    
                                            
    cis-13-Docosenamide
    
                                            
     Similarity: 0.77
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 34800-90-3
    
                                        
    
                                            
    [ 34800-90-3 ]
    
                                            
    2-(Naphthalen-1-yl)acetohydrazide
    
                                            
     Similarity: 0.74
    
                                        
    
                                    
    
                                
                                    
    
                                        
    Chemical Structure| 88-96-0
    
                                        
    
                                            
    [ 88-96-0 ]
    
                                            
    Phthalamide
    
                                            
     Similarity: 0.74
    
                                        
    
                                    
    
                                
                            
                        
                    
    
                
                
                
            
    
        
        
    
        
    

    
    

    







  
 

















;
;