REVIEW Brivanib inhibitors VEGFR -2 with an IC50 of 25 nmol/L and a Ki of 26 nmol/L, VEGFR-1 with an IC50 of 380nmol/L and VEGFR-3 with an IC50 of 10nmol/L. It also shows selectivity for FGFR-1 with an IC50 of 148 nmol/L, FGFR-2 with an IC50 of 25nmol/L and FGFR-3 with an IC50 of 68 nmol/L.
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