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REVIEW Dibenzo[b,E]oxepin-11(6H)-one is a key intermediate towards the preparation of doxepin, a tricyclic antidepressant and its analogues.
REFERENCES
[1]
Stach, K.; Spingler, H. New heterocyclic ring systems Angewandte Chemie (1962), 74, 31-2.
[2]
Stach, K.; Bickelhaupt, F. New heterocyclic ring-systems Angewandte Chemie (1962), 74, 752.
[3]
Winthrop, Stanley O.; Davis, M. A.; Herr, F.; Stewart, J.; Gaudry, Roger New psychotropic agents. III. Derivatives of 6,11-dihy-drodibenz[b,e]oxepine and 6,1 1-dihydrodibenzo[b,e]thiepine Journal of Medicinal & Pharmaceutical Chemistry (1962), 5, 1207-15.
[4]
Jalander, Lars; Oksanen, Lasse; Tahtinen, Johanna Synthesis of dothiepin and doxepin by Grignard reactions in toluene Synthetic Communications (1989), 19(19), 3349-52.
[5]
Wong, Jesse K.; Piwinski, John J.; Green, Michael J. Dibenzocycloheptenylidenepiperidine, dibenzocycloheptenylpiperazine, and heterocyclic analogs as PAF antagonists and antihistaminics U.S. (1995), US 5416087 A 19950516.
[6]
Limban, Carmen; Missir, Alexandru-Vasile; Chirita, Ileana Cornelia; Caproiu, Miron Teodor; Draghici, Constantin; Nitulescu, George Mihai Novel dibenz[b,e]oxepins derivatives Revista de Chimie (Bucharest, Romania) (2009), 60(12), 1313-1317.
[7]
Sadek, Bassem; Limban, Carmen; Stecoza, Camelia Elena; Elz, Sigurd Synthesis and antimicrobial evaluation of dibenzo[b,e]oxepin-11(6H)-one O-benzoyloxime derivatives Scientia Pharmaceutica (2011), 79(4), 749-761.
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