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  J10710    
Betamethasone
, 99% (HPLC)
 
Betadexamethasone
Flubenisolone
Rinderon
more..




IDENTITY
CAS Number:378-44-9
MDL Number:MFCD00062969
MF:C22H29FO5
MW:392.46
EINECS:206-825-4
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:255-258°C
Optical Rotation:+115° - +121° (c=1, Dioxane)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Water: 0.0063g/L (37°C)

REVIEW

 Betamethasone is glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. Betamethasone is a glucocorticoid receptor agonist.

REFERENCES
[1]Saraceno R, Gramiccia T, Frascione P, Chimenti S. Calcipotriene/betamethasone in the treatment of psoriasis: a review article. Expert Opin Pharmacother. (2009) Oct;10(14): 2357-65.
[2] Giardino G, Fusco A, Romano R, Gallo V, Maio F, Esposito T, Palamaro L, Parenti G, Salerno MC, Vajro P, Pignata C. Betamethasone therapy in ataxia telangiectasia: unraveling the rationale of this serendipitous observation on the basis of the pathogenesis. Eur J Neurol. (2013) May;20(5): 740-7.
[3] Basaran A, Basaran M, Sen C. Choice of glucocorticoid in HELLP syndrome - dexamethasone versus betamethasone: revisiting the dilemma. J Matern Fetal Neonatal Med. (2012) Dec;25(12): 2597-600.
[4] Taub, D.; Hoffsommer, R. D.; Slates, H. L.; Kuo, C. H.; Wendler, N. L.16beta-Methyl cortical steroids Journal of the American Chemical Society (1960), 82, 4012-26.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H360; H373

Precautionary Statements
P201; P202; P260; P281; P308+P313; P405; P501


Current as of February 27, 2025


Download SDS Request COA

All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Steroid Hormones


PubChem
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