REVIEW Amitraz is a non-systemic formamidine acaricide and insecticide. Its effectiveness is based on alpha-adrenergic agonist activity, interaction with octopamine receptors of the CNS and inhibition of monoamine oxidases and prostaglandin synthesis. Because amitraz is less harmful to mammals, it is also used as an animal ectoparasiticide.
REFERENCES
[1]
Harrison, Ian Robert; McCartny, John F.; Palmer, Bryan H.; Kozlik, Antonin Pesticidal 1,5-diphenyl-3-methyl-1,3,5-triazapenta-1,4-dienes Ger. Offen. (1971), DE 2061132 A 19710616.
[2]
Harrison, I. R.; Kozlik, A.; McCarthy, J. F.; Palmer, B. H.; Wakerley, S. B.; Watkins, T. I.; Weighton, D. M. 1,5-Bis(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-diene, a new acaricide active against strains of mites resistant to organophosphorus and bridged diphenyl compounds Pesticide Science (1972), 3(6), 679-80.
[3]
Kimmel, Ella C.; Casida, John E.; Ruzo, Luis O. Formamidine insecticides and chloroacetanilide herbicides: disubstituted anilines and nitrosobenzenes as mammalian metabolites and bacterial mutagens Journal of Agricultural and Food Chemistry (1986), 34(2), 157-61.
[4]
Hollingworth RM. Chemistry, biological activity, and uses of formamidine pesticides. Environ Health Perspect. 1976 Apr;14:57-69.
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