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  J10094    AKSci Reference Standard
Sulfachloropyridazine sodium
, >98% (HPLC)
 
Prinzone
Sodium[(4-aminophenyl)sulfonyl](6-chloropyridazin-3-yl)azanide
Sodium sulfachlorpyridazine




IDENTITY
CAS Number:23282-55-5
MDL Number:MFCD04117866
MF:C10H8ClN4NaO2S
MW:306.70
EINECS:245-553-0
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:262-270°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Sulfachloropyridazine sodium is a sulfonamide antibiotic used in humans and animals (dogs, horses, cows, and pigs) that is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. It blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfachloropyridazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. Mode of resistance is via the alteration of dihydropteroate synthase or an alternative pathway for folic acid synthesis. Sulfachloropyridazine is rapidly absorbed and rapidly excreted in the urine.

REFERENCES
[1]Nanda KG, Batterman RC Clinical use of sulfachloropyridazine. Ann N Y Acad Sci. 1957 Oct 12;69(3):521-4.NICOLAI CH. A clinical evaluation of a new sulfonamide: sulfachloropyridazine. Mo Med. 1962 Nov;59:1068-70.
[2] Constable PD.Antimicrobial use in the treatment of calf diarrhea. J Vet Intern Med. 2004 Jan-Feb;18(1):8-17.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS

Current as of October 31, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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CATEGORIES

 APIs and Bioactives > Antibacterials, Sulfonamides


PubChem
  @PubMed
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