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  H770    AKSci Bulk Reagent
Tetracaine HCl
, 98%
 
4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride




IDENTITY
CAS Number:136-47-0
MDL Number:MFCD00038912
MF:C15H25ClN2O2
MW:300.82
EINECS:205-248-5
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:130-149°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply to certain package sizes and shipment methods. Please check pricing table for an indicator of applicable hazmat fees.

BIOLOGICAL INFO
Solubility:H2O: 50mg/mL
Application(s):Channel function allosteric inhibitor
Form:HCl salt

REVIEW

 A potent local anesthetic. Tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

REFERENCES
[1]Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W (2011). Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 7(12):e1002310. PMID 22194678.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H301; H317; H319

Precautionary Statements
P261; P264; P270; P272; P280; P301+P310; P302+P352; P305+P351+P338; P321; P330; P333+P313; P337+P313; P363; P405; P501


RELATED PRODUCTS
K715Tetracaine
H770Tetracaine HCl

Current as of November 16, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Anaesthetics


PubChem
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