| Identification | More | [Name]
2-Amino-4-phenylbutane | [CAS]
22374-89-6 | [Synonyms]
(+/-)-AMPHETAMINE
AURORA KA-7110
DL-AMPHETAMINE
.alpha.-Methyl-.gamma.-phenyl-n-propylamine
.alpha.-methyl-.gamma.-phenyl-Propylamine
1-methyl-3-phenyl-propylamin
1-Phenyl-3-amino-butan
1-Phenyl-3-aminobutane
3-Phenyl-1-methylpropylamine
4-Phenyl-2-aminobutane
alpha-methyl-benzenepropanamin
alpha-Methyl-gamma-phenyl-n-propylamin
alpha-Methyl-gamma-phenyl-N-propylamine
alpha-methyl-gamma-phenyl-propylamin
Propylamine, 1-methyl-3-phenyl-
Propylamine, alpha-methyl-gamma-phenyl-
Propylamine,.alpha.-methyl-.gamma.-phenyl-
α-Methylbenzenepropylamine
2-Amino-4-phenylbutane, 98+%
(n)-3-amino-1-phenylbutane | [EINECS(EC#)]
244-942-2 | [Molecular Formula]
C10H15N | [MDL Number]
MFCD00056185 | [Molecular Weight]
149.23 | [MOL File]
22374-89-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Melting point ]
-50°C | [Boiling point ]
228-232 °C (lit.) | [density ]
0.922 g/mL at 25 °C(lit.)
| [vapor pressure ]
10.146Pa at 25℃ | [refractive index ]
n20/D 1.514(lit.)
| [Fp ]
208 °F
| [storage temp. ]
−20°C | [solubility ]
soluble in Chloroform, Ethyl Acetate | [form ]
liquid | [pka]
pKa 10.0 (Uncertain) | [color ]
Clear | [Specific Gravity]
0.922 | [PH]
11.6 (10g/l, H2O, 20℃) | [Water Solubility ]
8.5 g/L (20 ºC) | [Sensitive ]
Air Sensitive | [BRN ]
2413110 | [LogP]
2.12 | [CAS DataBase Reference]
22374-89-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzenepropanamine, «alpha»-methyl-(22374-89-6) |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xi,T,F | [Risk Statements ]
R34:Causes burns.
R22:Harmful if swallowed.
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
UN 2735 8/PG 3
| [WGK Germany ]
2
| [RTECS ]
UI3920000
| [Hazard Note ]
Irritant | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29214980 | [Toxicity]
LD orl-rat: >600 mg/kg AEPPAE 195,647,1940 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Uses]
2-Amino-4-phenylbutane is used in the synthesis of N-substituted derivatives of (1-methyl-3- phenylpropyl)amine.
| [Biological Functions]
Amphetamine is an indirectly acting adrenomimetic
amine that depends for its action on the release of norepinephrine
from noradrenergic nerves. Its pharmacological
effects are similar to those of ephedrine; however,
its CNS stimulant activity is somewhat greater.
Both systolic and diastolic blood pressures are increased
by oral dosing with amphetamine. The heart rate is frequently
slowed reflexively. Cardiac output may remain
unchanged in the low- and moderate-dose range.
The therapeutic uses of amphetamine are based on
its ability to stimulate the CNS. The D-isomer (dextroamphetamine)
is three to four times as potent as the
L-isomer in producing CNS effects. It has been used in
the treatment of obesity because of its anorexic effect,
although tolerance to this effect develops rapidly. It
prevents or overcomes fatigue and has been used as a
CNS stimulant. Amphetamine is no longer recommended
for these uses because of its potential for abuse.
Amphetamine is useful in certain cases of narcolepsy or
minimal brain dysfunction. | [Flammability and Explosibility]
Notclassified | [Safety Profile]
A poison by intraperitoneal and parenteral route. Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors of NOx. | [Synthesis]
Amphetamine is prepared by treating phenylacetone
with formic acid and ammonia under
the Leuckart-Wallach conditions . |
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