| Product Identification | Back to Contents | 【Product Name】
Pseudoephedrine | 【Synonyms】
D-Isoephedrine
D-psi-Ephedrine
Isoephedrine
psi-Ephedrin
Psi-Ephedrine
trans-Ephedrine | 【CAS】
90-82-4 | 【Formula】
C10H15NO | 【Molecular Weight】
165.26 | 【EINECS】
202-018-6 | 【RTECS】
UL5800000 | 【RTECS Class】
Drug; Human Data | 【Beilstein/Gmelin】
2414132 | 【Beilstein Reference】
4-13-00-01878 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Rhombic tablets from ether. | 【Solubility in water】
Very soluble | 【Melting Point】
58 - 59 | 【Boiling Point】
255 | 【Vapor Pressure】
0.009 (25 C) | 【Density】
1.118 g/cm3 | 【pKa/pKb】
4.62 (pKb) | 【Partition Coefficient】
1.05 | 【Heat Of Vaporization】
52.0 kJ/mol | 【Usage】
Medication. |
| First Aid Measures | Back to Contents | 【Ingestion】
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Skin】
Fixed drug eruptions, pseudo-scarlatina and systemic contact dermatitis have been reported. | 【Ingestion】
Anorexia, nausea, and vomiting are common. Ischemic colitis has been associated with therapeutic pseudoephedrine administration. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Not available. | 【Exposure Effects】
Elevated blood pressure may occur, usually accompanied by rapid heart rate. Reduced body temperature and abnormally low blood pressure were reported in a case of a mixed drug overdose. anxiety, nervousness, insomnia, muscle tremor, seizures, and altered mental status may be noted. Drowsiness has been seen after overdose in children. Intracerebral hemorrhage has occurred. Hallucinations may occur, particularly in children. Coma has occurred in a mixed drug overdose. Pseudoephedrine is US FDA Pregnancy Category C. It is excreted in breast milk in low amounts. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
89 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
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