Zonisamide NEW
| Price | $40 | $59 | $79 |
| Package | 50mg | 100mg | 200mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-16 |
Product Details
| Product Name: Zonisamide | CAS No.: 68291-97-4 |
| Purity: 99.94% | Supply Ability: 10g |
| Release date: 2024/11/16 |
Product Introduction
Bioactivity
| 名稱 | Zonisamide |
| 描述 | Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels results in a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may lower the uptake of the inhibitory neurotransmitter GABA while increasing the uptake of the excitatory neurotransmitter glutamate. |
| 體外活性 | Zonisamide inhibits monoamine oxidase B activity in vitro with an IC50 of 25 μM. |
| 體內(nèi)活性 | Zonisamide inhibits monoamine oxidase B activity in vitro with an IC50 of 25 μM. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 55 mg/mL (259.15 mM) |
| 關(guān)鍵字 | parkinson’s disease | seizure | epilepsy | Carbonate dehydratase | AD-810 | Apoptosis | Inhibitor | cardiac hypertrophy | cardiac fibroblasts | inhibit | AD810 | Zonisamide | CI-912 | CI912 | Carbonic Anhydrase | NRCMs | SH-SY5Y |
| 相關(guān)產(chǎn)品 | Nisoldipine | Benzenesulfonamide | Phenytoin sodium | Cyclamic acid sodium | L-Ascorbic acid | Lidocaine | Lidocaine hydrochloride | L-Aspartic aicd sodium | Ethyl cinnamate | 1-Octanol |
| 相關(guān)庫 | 疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | EMA 上市藥物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 神經(jīng)保護(hù)化合物庫 | FDA 上市藥物庫 | 離子通道庫 | 抗癌藥物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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