Zinc pyrithione NEW
| Price | $35 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Zinc pyrithione | CAS No.: 13463-41-7 |
| Purity: 99.64% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Zinc pyrithione |
| Description | Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump. |
| In vitro | In exposed mussel tissues, Zinc pyrithione accumulates rapidly, with the rate of accumulation being proportional to both exposure concentration and time. Despite a 7-day LC50 (lethal concentration for 50% of the population) of 8.27 μM in relatively higher concentrations of Zinc pyrithione, this indicates a potential threat to coastal ecosystems and marine life, necessitating further investigation into its sub-lethal biological effects. |
| In vivo | As a specific synthetic potentiator, Zinc pyrithione activates homotypic and heterotypic M channels by inducing a resting potential. It is considered a zinc complex. The Pyrithione ligand (formally a monoanion) chelates with Zn2+ through oxygen and iron-sulfur centers. In the crystalline state, Zinc pyrithione exists as a centrosymmetric dimer, with each zinc atom coordinated to two sulfur and three oxygen centers. However, in solution, the dimers dissociate through the cleavage of zinc-oxygen bonds. Although Zinc pyrithione is a dimer, its activity causing cytoplasmic membrane depolarization may originate from the monomer, with an effective concentration for half-maximum effect (K1/2) of approximately 0.3 mM. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 20 mg/mL (62.95 mM), Sonication is recommended. |
| Keywords | Bacterial | inhibit | Inhibitor | Proton Pump | OM1563 | Fungal | OM 1563 | Zinc pyrithione |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Potassium gluconate | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Geraniol | Dimethyl sulfoxide | Crystal Violet |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Fungal Compound Library | FDA-Approved Drug Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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