Zanamivir NEW
| Price | $45 | $72 | $112 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Zanamivir | CAS No.: 139110-80-8 |
| Purity: 99.98% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Zanamivir |
| Description | Zanamivir (GG167) is a guanido-neuraminic acid that is used to inhibit NEURAMINIDASE. |
| In vitro | Zanamivir reduces pulmonary viral titers and decreases morbidity and mortality rates in a lethal murine model infected with the virus. |
| In vivo | Zanamivir effectively reduces viral replication in vitro by inhibiting the influenza neuraminidase and preventing the cleavage of sialic acid residues. This interference blocks the spread of progeny viruses in mucosal secretions and lowers viral infectivity. Furthermore, Zanamivir diminishes the area of plaques formed by neuraminidase-deficient mutants, indicating that its action in disrupting cell-cell fusion is independent of its neuraminidase inhibition activity. The compound also prevents the adhesion and fusion of persistently infected cells with uninfected erythrocytes. Assessment through lipid mixing and content mixing reveals that Zanamivir does not affect erythrocyte adhesion but does inhibit HA2b-red blood cell fusion. Additionally, Zanamivir leads to decreased sensitivity in influenza A/H1N1 variants His274Asn, His274 gly, His274Ser, and His274 gln. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 10 mg/mL (30.09 mM), Sonication and heating are recommended. DMSO : <1 mg/mL (Insoluble) |
| Keywords | GG 167 | inhibit | Zanamivir | Inhibitor | GG-167 | Influenza Virus | Antibiotic |
| Inhibitors Related | Neomycin sulfate | Ampicillin sodium | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Curcumin | EDTA copper(II) disodium salt | Crystal Violet |
| Related Compound Libraries | Bioactive Compound Library | EMA Approved Drug Library | Antibiotics Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Inhibitor Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Anti-COVID-19 Compound Library | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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