Zamicastat NEW
| Price | $88 | $215 | $325 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Zamicastat | CAS No.: 1080028-80-3 |
| Purity: 99.58% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Zamicastat |
| 描述 | Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH) and a concentration-dependent dual inhibitor of P-gp and BCRP, with IC50 values of 73.8 μM and 17.0 μM, respectively. |
| 體內(nèi)活性 | In the Dahl SS rat, Zamicastat (10, 30 and 100 mg/kg/day; oral bolus, 7 days) is tested acutely against salt-induced hypertension. Zamicastat produces a dose-dependent decrease in blood pressure[2]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 150 mg/mL (373.63 mM), Sonication is recommended. |
| 關(guān)鍵字 | ABCB1 | Dopamine β-monooxygenase | Inhibitor | Cluster of differentiation 243 | ABCG2 | inhibit | P-glycoprotein | Multidrug resistance protein 1 | BCRP | MDR1 | CD243 | Breast cancer resistance protein | P-gp | Pgp | Zamicastat | Dopamine β-hydroxylase | Dopamine beta-hydroxylase | Dopamine beta-monooxygenase |
| 相關(guān)產(chǎn)品 | Atazanavir | Verapamil hydrochloride | Glibenclamide | Encequidar mesylate | Casein | Ketoconazole | Polyoxyethylene stearate | Elacridar | P-gp inhibitor 1 | Fenclonine | Cinchonine | Atazanavir sulfate |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 神經(jīng)信號分子庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗心血管疾病化合物庫 | 已知活性化合物庫 | 離子通道庫 | 抗癌藥物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $88.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-14 | |
| $1.10/1g |
VIP4Y
|
Dideu Industries Group Limited
|
2021-08-17 | |
| $1.00/1g |
VIP5Y
|
Career Henan Chemical Co
|
2019-12-23 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY