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Postion:Product Catalog >X-376
X-376
  • X-376

X-376 NEW

Price $30 $43 $89
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: X-376 CAS No.: 1365267-27-1
Purity: 98.72% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱X-376
描述X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.
體外活性Ensartinib is a selective ALK inhibitor, and provids promising advantages in terms of both Clinicalal activity and safety[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 37 mg/mL (67.59 mM)
關(guān)鍵字inhibit | X-376 | X 396 | X376 | ALK tyrosine kinase receptor | Cluster of differentiation 246 | X 376 | c-Met/HGFR | X396 | CD246 | Inhibitor | Anaplastic lymphoma kinase | Anaplastic lymphoma kinase (ALK)
相關(guān)產(chǎn)品SB-431542 | DMH-1 | RepSox | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | Ceritinib | Cabozantinib S-malate | A 83-01 | ALK-IN-1
相關(guān)庫經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 已知活性化合物庫 | 抗癌藥物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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