X-376 NEW
Price | $30 | $43 | $89 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: X-376 | CAS No.: 1365267-27-1 |
Purity: 98.72% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱 | X-376 |
描述 | X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development. |
體外活性 | Ensartinib is a selective ALK inhibitor, and provids promising advantages in terms of both Clinicalal activity and safety[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 37 mg/mL (67.59 mM) |
關(guān)鍵字 | inhibit | X-376 | X 396 | X376 | ALK tyrosine kinase receptor | Cluster of differentiation 246 | X 376 | c-Met/HGFR | X396 | CD246 | Inhibitor | Anaplastic lymphoma kinase | Anaplastic lymphoma kinase (ALK) |
相關(guān)產(chǎn)品 | SB-431542 | DMH-1 | RepSox | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | Ceritinib | Cabozantinib S-malate | A 83-01 | ALK-IN-1 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 已知活性化合物庫 | 抗癌藥物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$68.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$79.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co Ltd
|
2024-12-17 | |
$2170.00/1tons |
VIP3Y
|
Hebei Dangtong Import and export Co LTD
|
2023-02-22 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY