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Postion:Product Catalog >VU 0240551
VU 0240551
  • VU 0240551

VU 0240551 NEW

Price $31 $71 $127
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: VU 0240551 CAS No.: 893990-34-6
Purity: 99.72% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱VU 0240551
描述VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.
體外活性VU 0240551 (0-100 μM) reduces the P cell response to GABA in a concentration-dependent manner and significantly reduces GABA-elicited hyperpolarization at doses of 75 and 100 μM[3].
體內(nèi)活性VU 0240551 (10 μM) significantly inhibits chloride influx in cells from euhydrated rats, but does not affect cells from salt-loaded rats[4].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度H2O : Insoluble
DMSO : 45 mg/mL (131.41 mM), Sonication is recommended.
關(guān)鍵字VU 0240551 | VU0240551 | VU-0240551
相關(guān)產(chǎn)品Minoxidil sulfate | Nisoldipine | Diltiazem hydrochloride | Levetiracetam | L-Ascorbic acid | Lanthanum(III) chloride heptahydrate | Halothane | Neratinib | Ethyl cinnamate | 1-Octanol | Cloperastine hydrochloride | Indapamide
相關(guān)庫抗肺癌化合物庫 | 抗胰腺癌化合物庫 | 經(jīng)典已知活性庫 | 疼痛相關(guān)化合物庫 | 神經(jīng)信號(hào)分子庫 | 膜蛋白靶向化合物庫 | 酪氨酸激酶分子庫 | 抑制劑庫 | 已知活性化合物庫 | 離子通道庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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