Product Details
Product Name:
Vorozole |
CAS No.:
129731-10-8 |
Purity:
99% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Vorozole |
Description | Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the study of breast cancer. |
In vitro | Vorozole inhibits aromatase activity in FSH-stimulated rat granulosa cells with an IC 50 s of 1.4 nM.[3] |
In vivo | Vorozole (0.8-1.25 mg/kg; Gavage; daily for 77 days; Female Sprague-Dawley rats) demonstrates antitumor effects and increases serum levels of insulin-like growth factor (IGF)-1 and testosterone.[3] Additionally, Vorozole (0.8-1.25 mg/kg; p.o.; 5 days; Female Sprague-Dawley rats) reduces uterine weight in a dose-dependent manner and effectively suppresses tumor aromatase in ovariectomized nude mice.[3] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 50 mg/mL (153.96 mM)
|
Keywords | R-83842 | R 83842 | Vorozole |
Inhibitors Related | Naringin | Naringenin |
Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |