Factory Provide Top Quality Tretinoin / Retinoic Acid / Vitamin a Acid CAS 302-79-4

Introduction

Product Name :Vitamin a Acid 

Other name:TRETINOIN;TRETINOIN VITAMIN A ACID;TRANS-RETINOIC ACID;TRANS VITAMIN A ACID;VITAMIN A ACID;

CAS No.: 302-79-4

MF:C20H28O2

MW:300.44

Specification:99%

Appearance: Yellow powder or crystal 

Melting Point :180-181 °C (lit.)

Boiling Point :381.66°C (rough estimate)

Density :1.0597 (rough estimate)

Storage :Keep in dark place,Inert atmosphere,Room temperature

Retinoic Acid Powder is yellow crystalline powder. Retinoic Acid Powder easily dissolved in chloro and dissolved in carbinol, ethanol and retinoic acid also dissolved in vegetable oil and lipid. Retinoic Acid Powder instability exposed in light and caloricr, easily absorbing moisture and metamorphosed in water. Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic.

Retinoic Acid/Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA.    It is a drug commonly used to treat acne vulgaris and keratosis pilaris.    It is available as a cream or gel It is also used to treat acute promyelocytic leukemia.    It is also available as a generic.

Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.   It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia  gene.

This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells.    This block in differentiation is thought to cause leukemia.

Function:
1.   Retinoic Acidis a drug commonly used to treat acne vulgaris and keratosis pilaris.
2.   Retinoic Acid is available as a cream or gel.   It is also used to treat acute promyelocytic leukemia.
3.   Retinoic Acid can stimulate skin growth and keep epidermic normal.
4.   Retinoic Acid can slow down skin aging process for solarization, remove tiny wrinkles.
5.   Retinoic Acid can reduce skin roughness, so skin will become ruddy.
Application:
1.   Retinoic Acid /Tretinoin is widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc.
2.   Retinoic Acid /Tretinoin can be made into tretinoin or retinoic acid cream to cureacne or other unhealthy skin.
3.   Retinoic Acid/Tretinoin is used for skin keratinocytes-resistant drugs and cell-induced differentation drug.