VEGFR-2-IN-9 NEW
| Price | $700 | $1800 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-16 |
Product Details
| Product Name: VEGFR-2-IN-9 | CAS No.: 408502-06-7 |
| Purity: 97.19% | Supply Ability: 10g |
| Release date: 2024/11/16 |
Product Introduction
Bioactivity
| 名稱 | VEGFR-2-IN-9 |
| 描述 | VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor with an IC50 of 7 nM, suitable for breast cancer research. |
| 體外活性 | One of the human tyrosine kinases with a high affinity for vascular endothelial growth factor (VEGF) is KDR (kinase insert domain-containing receptor), believed to be a primary mediator of tumor-induced angiogenesis[2]. |
| 體內(nèi)活性 | KDR-in-4, at doses of 100 mg/kg, results in a 98% reduction in lesion size in the rat choroidal neovascularization (CNV) model, demonstrating potential utility for the treatment of various ocular neovascular diseases through a convenient oral dosing regimen. In the laser CNV and rat oxygen-induced retinopathy (OIR) models, 30 mg/kg doses of KDR-in-4 exhibit reductions in lesion size of 70% and 80%, respectively[1]. |
| 存儲(chǔ)條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 關(guān)鍵字 | VEGFR-2-IN-9 |
| 相關(guān)產(chǎn)品 | Ribociclib | Nintedanib | Regorafenib monohydrate | Sorafenib | Regorafenib | Sanguinarine chloride | Sorafenib tosylate | Lenvatinib mesylate | Pazopanib | Axitinib |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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