Vancomycin hydrochloride NEW
| Price | $54 |
| Package | 1g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Vancomycin hydrochloride | CAS No.: 1404-93-9 |
| Purity: 99.19% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Vancomycin hydrochloride |
| Description | Vancomycin hydrochloride (Vancomycin HCl) is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. |
| In vitro | Vancomycin, a substantial glycopeptide antibiotic with a molecular weight of 1450 Da[1], stands out due to its unique structure and mode of action, distinguishing it from all currently available antibiotics. Its distinctive mechanism targets and inhibits the second stage of cell wall synthesis in susceptible bacteria. Active against an extensive array of Gram-positive species including Staphylococcus aureus, Staph. epidermidis, Str. agalactiae, Str. bovis, Str. mutans, viridans streptococci, and enterococci[2], vancomycin is a critical asset in treating various bacterial infections. |
| In vivo | Vancomycin is administered via intravenous infusion over a minimum of one hour to reduce the risk of infusion-related adverse effects. In individuals with normal creatinine clearance levels, the distribution phase (α) of vancomycin spans between 30 minutes to 1 hour, while the elimination half-life (β) ranges from 6 to 12 hours. Its distribution volume lies between 0.4–1 L/kg, and its protein-binding capacity varies between 10% and 50%. The efficacy of vancomycin is influenced by factors such as tissue distribution, inoculum size, and protein-binding impacts. Furthermore, vancomycin therapy in infected mice demonstrates significant improvements in clinical outcomes, diarrhea, histopathological scores, and survival rates during the course of treatment. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 33.33 mg/mL (22.43 mM), Sonication is recommended. DMSO : 55 mg/mL (37.02 mM), Sonication and heating are recommended. |
| Keywords | inhibit | Autophagy | Antibiotic | Vancomycin Hydrochloride | Bacterial | Vancomycin | Inhibitor | Vancomycin hydrochloride |
| Related Compound Libraries | Cyclic Peptide Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Natural Product Library | Microbial Natural Product Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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