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Postion:Product Catalog >UCB7362
UCB7362
  • UCB7362

UCB7362 NEW

Price $579 $1270 $1980
Package 1mg 5mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-16

Product Details

Product Name: UCB7362 CAS No.: 2610631-17-7
Purity: 97.38% Supply Ability: 10g
Release date: 2024/11/16

Product Introduction

Bioactivity

名稱UCB7362
描述UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.
體外活性UCB7362 exhibits significantly higher potency against PMX than PMIX, with an IC50 of 7 nM for the former compared to 142 nM for the latter[1]. Additionally, UCB7362 demonstrates improved selectivity against Cat D and Renin, with an IC50 of 3889 nM and >10,000 nM, respectively[1].
體內(nèi)活性UCB7362, when administered orally at doses ranging from 10 to 60 mg/kg twice a day for 4 days, clears parasitemia from peripheral blood[1]. Furthermore, when given intravenously (IV) at 1 mg/kg and orally (PO) at 10 mg/kg in a single administration, UCB7362 exhibits moderate clearance in dogs and cynomolgus monkeys, and moderate to high clearance in rats[1].
存儲條件Shipping with blue ice.
關(guān)鍵字UCB-7362 | UCB 7362 | UCB7362
相關(guān)產(chǎn)品Picaridin | PHYTOL | Kaempferol | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Diethyltoluamide | Artemisinin | Benzyl benzoate | DL-Methionine
相關(guān)庫抗寄生蟲庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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