Tyrphostin AG1433 NEW
Price | $44 | $98 | $163 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Tyrphostin AG1433 | CAS No.: 168835-90-3 |
Purity: 97.51% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | Tyrphostin AG1433 |
描述 | Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM). |
體外活性 | In glioblastoma cells, Tyrphostin AG1433 (0.1-100 μM; 72 hours; GB8B cells) treatment induces moderate cytotoxicity [1]. |
體內(nèi)活性 | Tyrphostin AG1433 is prepared in methylcellulose pellets and applies to the CAMs of 4-6-day-old chicken embryos, and prevents the formation of new yessels under the pellets[2]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 3.06 mg/mL (11.47 mM), Sonication is recommended. |
關(guān)鍵字 | cytotoxicity | PDGFRβ | Tyrphostin AG-1433 | VEGFR | kinases | Vascular endothelial growth factor receptor | SU 1433 | Tyrphostin AG1433 | Tyrphostin AG 1433 | Platelet-derived growth factor receptor | AG-1433 | angiogenesis,tyrosine | inhibit | AG 1433 | VEGFR-2 | Inhibitor | ATM | SU-1433 | PDGFR |
相關(guān)產(chǎn)品 | Ribociclib | Nintedanib | Regorafenib monohydrate | Imatinib Mesylate | Sorafenib | Regorafenib | Sanguinarine chloride | Sorafenib tosylate | Lenvatinib mesylate | Imatinib | Pazopanib | Axitinib |
相關(guān)庫 | 抗胰腺癌化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | 抗乳腺癌化合物庫 | 抑制劑庫 | 抗心血管疾病化合物庫 | 已知活性化合物庫 | 抗肝癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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