Product Details
Product Name:
XL 999 |
CAS No.:
705946-27-6 |
Purity:
99.55% |
Supply Ability:
10g |
Release date:
2024/11/14 |
Product Introduction
Bioactivity
名稱 | XL 999 |
描述 | Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor that acts on KDR, Flt-1, FGFR1, and PDGFRα with IC50 values of 4 nM, 20 nM, 4 nM, and 2 nM, respectively. |
體內(nèi)活性 | Tyrosine kinase-IN-1 demonstrates a reasonable pharmacokinetic profile [AUC(0–∞)=1.9, t1/2=4.6 h] and possesses favorable oral bioavailability (F=63%) in rats. |
存儲條件 | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 62.5 mg/mL (160.47 mM)
|
關(guān)鍵字 | VEGFR | Vascular endothelial growth factor receptor | Tyrosine kinase-IN-1 | Tyrosine kinaseIN1 | Tyrosine kinase IN 1 | Platelet-derived growth factor receptor | PDGFR | Inhibitor | inhibit | Fibroblast growth factor receptor | FGFR |
相關(guān)產(chǎn)品 | Ribociclib | Gilteritinib | Amlexanox | Nintedanib | Regorafenib monohydrate | Sorafenib | Ferulic Acid | Regorafenib | Formononetin | Imatinib | Pazopanib | Axitinib |
相關(guān)庫 | 抗結(jié)直腸癌化合物庫 | 成骨分子庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 酪氨酸激酶分子庫 | 激酶抑制劑庫 | 抗卵巢癌化合物庫 | 抑制劑庫 | 抗纖維化化合物庫 | 抗心血管疾病化合物庫 | 已知活性化合物庫 | 抗癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
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Suppliers |
Update time |
|
$1820.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |
|
$32.00/10kg |
VIP3Y
|
Hebei Dangtong Import and export Co LTD
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2023-03-03 |