Product Details
Product Name:
TUG-499 |
CAS No.:
1206629-08-4 |
Purity:
99.59% |
Supply Ability:
10g |
Release date:
2024/11/16 |
Product Introduction
Bioactivity
名稱 | TUG-499 |
描述 | TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39). It shows higher affinity for FFAR1 or GPR40 relative to related receptors FFA2, FFA3, and the nuclear receptor PPARγ, as well as various other receptors, ion channels, and transporter proteins. TUG-499 is useful for studying Type 2 diabetes. |
體外活性 | TUG-499 exhibits remarkable chemical stability, does not inhibit specific CYP enzymes or P-glycoprotein, and displays outstanding Caco-2 permeability. Its potent effects are observed on recombinant human FFA1 receptors as well as the INS-1E rat insulinoma cell line.[1] |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 22.5 mg/mL (70.28 mM)
|
關鍵字 | TUG 499 | TUG-499 | TUG499 |
相關產(chǎn)品 | PHYTOL | (S)-(+)-Ibuprofen | BADGE | Daidzein | Fenofibrate | Pioglitazone hydrochloride | 5-Aminosalicylic Acid | Benzyl nicotinate | Naringenin | Fisetin | 2,3-Butanediol | Icariin |
相關庫 | 核受體化合物庫 | DNA 損傷和修復分子庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抗肥胖化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | GPCR靶點分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:2247372-59-2
$135.00 / 1mg
-
CAS:1082058-99-8
$74.00 / 1mg
-
CAS:1236109-67-3
$39.00 / 10mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$2800.00/100mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |
|
$58.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |
|
$1.00/1KG |
VIP5Y
|
Career Henan Chemical Co
|
2019-12-25 |