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Postion:Product Catalog >Tizaterkib
Tizaterkib
  • Tizaterkib

Tizaterkib NEW

Price $96 $139 $231
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Tizaterkib CAS No.: 2097416-76-5
Purity: 99.6% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTizaterkib
DescriptionTizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.
In vitroAZD-0364 is measured in the ERK2 mass spectrometry and A375 phospho-p90RSK assays (IC50s: 0.6 nM and 5.7 nM). AZD-0364 can inhibit the growth of a panel of cancer cell lines (A549, H2122, H2009, and Calu6 cell lines) with KRAS mutations as monotherapy.
In vivoIn the A549 xenograft model, Selumetinib is dosed twice daily (BiD) 8 hours apart and AZD-0364 ethanesulfonic acid is dosed once daily (QD) 4 hours after the first Selumetinib dose. Both compounds are dosed continuously for 3 weeks. Both vehicles are dosed in the vehicle group. Both Selumetinib and AZD-0364 ethanesulfonic acid reduce tumor growth relative to vehicle-only control. The combination of Selumetinib and AZD-0364 ethanesulfonic acid results in a reduction in tumor growth.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (202.22 mM)
Keywordsinhibit | ERK | AZD0364 | Inhibitor | Tizaterkib | Extracellular signal regulated kinases | AZD 0364
Inhibitors RelatedTBHQ | Notoginsenoside R1 | Lidocaine | Ro-3306 | Astragaloside IV | Olomoucine | Lidocaine hydrochloride | Selumetinib | Tauroursodeoxycholate sodium | Honokiol | Tauroursodeoxycholate | ROCK-IN-5
Related Compound LibrariesAnti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Anti-Ovarian Cancer Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$96.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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