Tipepidine hydrochloride NEW
Price | $33 | $52 | $77 |
Package | 2mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-15 |
Product Details
Product Name: Tipepidine hydrochloride | CAS No.: 1449686-84-3 |
Purity: 100.00% | Supply Ability: 10g |
Release date: 2024/11/15 |
Product Introduction
Bioactivity
名稱 | Tipepidine hydrochloride |
描述 | Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect. |
體內(nèi)活性 | In ACTH-treated rats, Tipepidine (i.p.; 10-40 mg/kg; 0.5-23 hours) significantly decreases the immobility time in the forced swimming test. In ACTH-treated rats, Tipepidine (i.p.; 40 mg/kg) increases the extracellular dopamine level of the nucleus accumbens (NAc) [2]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 50 mg/mL (160 mM) DMSO : 41.67 mg/mL (133.60 mM), Sonication is recommended. |
關(guān)鍵字 | KcsA | inhibit | Tipepidine hydrochloride | Tipepidine | Potassium Channel | Inhibitor | Tipepidine Hydrochloride |
相關(guān)產(chǎn)品 | Minoxidil sulfate | Olanzapine | CLOZAPINE N-OXIDE | Mirtazapine | Octopamine hydrochloride | Halothane | Citicoline | Cloperastine hydrochloride | Oxolinic acid | 2,2,2-Trichloroethanol | Mianserin hydrochloride | Indapamide |
相關(guān)庫 | 神經(jīng)退行性疾病化合物庫 | 疼痛相關(guān)化合物庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗癌上市藥物庫 | 已知活性化合物庫 | 離子通道庫 | GPCR靶點分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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