Thalidomide-O-amido-PEG-C2-NH2 hydrochloride NEW
Price | $51 | $74 | $122 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-09 |
Product Details
Product Name: Thalidomide-O-amido-PEG-C2-NH2 hydrochloride | CAS No.: 2204226-02-6 |
Purity: 95% | Supply Ability: 10g |
Release date: 2024/11/09 |
Product Introduction
Bioactivity
名稱(chēng) | Thalidomide-O-amido-PEG-C2-NH2 hydrochloride |
描述 | Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs. |
體外活性 | PROTACs consist of two ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade these target proteins [1]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 100 mg/mL (219.85 mM), Sonication is recommended. DMSO : 125 mg/mL (274.81 mM), Sonication is recommended. |
關(guān)鍵字 | Inhibitor | Thalidomide-O-amido-PEG-C2-NH2 Hydrochloride | Thalidomide-O-amido-PEG-C-2-NH2 hydrochloride | ThalidomideOamidoPEGC2NH2 hydrochloride | inhibit | Thalidomide O amido PEG C2 NH2 hydrochloride | E3 Ligase Ligand-Linker Conjugates |
相關(guān)產(chǎn)品 | Thalidomide-O-amido-PEG2-C2-NH2 TFA | (S,R,S)-AHPC-PEG2-NH2 hydrochloride | Thalidomide-O-amido-C6-NH2 hydrochloride | Thalidomide-O-amido-PEG3-C2-NH2 TFA | (S,R,S)-AHPC-PEG3-N3 | Thalidomide-NH-C2-PEG3-OH | Pomalidomide 4'-PEG3-azide | Pomalidomide-C2-NH2 hydrochloride | Thalidomide-O-amido-C4-NH2 TFA | Thalidomide-O-C6-NH2 hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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