Tenofovir Disoproxil Fumarate NEW
| Price | Get Latest Price |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | 1000kg |
| Update Time: | 2024-04-25 |
Product Details
| Product Name: Tenofovir Disoproxil Fumarate | CAS No.: 202138-50-9 |
| EC-No.: 687-766-5 | Min. Order: 1kg |
| Purity: 99% | Supply Ability: 1000kg |
| Release date: 2024/04/25 |
Hot Selling High Quality CAS. 202138-50-9 Tenofovir Disoproxil Fumarate Powder
Introduction
Product Name:Tenofovir Disoproxil Fumarate
Synonyms: Tenofovir dipivoxil FuMarate(TDF);2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(2,2-dimethylpropyl) ester, 5-oxide, (R)-
CAS No. 202138-50-9
EINECS: 687-766-5
Molecular Formula: C23H34N5O14P
Molecular Weight: 635.52
Specification: 98%
Appearance:White powder
Melting Point :113-115°C
Storage:Keep in dark place,Sealed in dry,Room Temperature
Tenofovir disoproxil is an antiretroviral drug used for the prevention and treatment of HIV/AIDS and chronic hepatitis B. The active substance is tenofovir, and tenofovir disoproxil is a prodrug, which is used for its better absorption in the intestinal tract. Tenofovir is a defective adenosine nucleotide that selectively inhibits the action of reverse transcriptase while only weakly interfering with mammalian DNA polymerase α, β and mitochondrial DNA polymerase γ. Tenofovir prevents the formation of 5' to 3' phosphodiester bonds necessary for DNA chain elongation.
| ITEMS | STANDARDS | RESULTS | |
Appearance | White or off-white crystalline powder | Off-white crystalline powder | |
| Identification | By IR | Complies | |
| RT under chirality should complies | Complies | ||
| Chloride: it gives a reaction of chloride | Complies | ||
| Water | 3.0%~4.5% | 3.4% | |
Melting Point | 198.0~202.0oC | 199.8~200.5oC | |
| Residue on Ignition | ≤0.2% | 0.08% | |
| Heavy Metals | ≤10ppm | Complies | |
| Related Substances | Individual Impurities:≤0.5% | 0.15% | |
| Total Impurities:≤1.0% | 0.22% | ||
| Residual Solvent | ≤0.06% | 0.0066% | |
| ≤0.5% | 0.015% | ||
| ≤0.5% | 0.0013% | ||
| E.E | ≥99.0% | 99.6% | |
Assay (on dry basis) | 98.0%~102.0% | 101.2% | |
| Conclusion:It complies to prescribed enterprise standard. | |||
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