Product Details
Product Name:
Tegaserod |
CAS No.:
145158-71-0 |
Purity:
99.89% |
Supply Ability:
10g |
Release date:
2024/11/12 |
Product Introduction
Bioactivity
名稱(chēng) | Tegaserod |
描述 | Tegaserod is an orally available 5-HT4R agonist and 5-HT2B receptor antagonist with inhibitory effects on various 5-hydroxytryptamine receptors. Tegaserod has antitumor activity and is used in the treatment of irritable bowel syndrome (IBS). |
體外活性 | Tegaserod ( 3,5 μM; 24,48,72 h ) increased the apoptosis of A375, RPMI-7951 ( RPMI ), SH4, B16F10, MeWo and MEL-JUSO cell lines in a time- and dose-dependent manner[1]. |
體內(nèi)活性 | After subcutaneous injection of B16F10 cells in C57BL / 6J mice, tegaserod ( 5 mg / kg ; 1 times a day for 5 consecutive days ) significantly reduced tumor growth, and only a slight decrease in body weight was observed after treatment[1]. |
存儲(chǔ)條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 30 mg/mL (99.54 mM), Sonication is recommended.
|
相關(guān)產(chǎn)品 | Alverine citrate | Olanzapine | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Amitriptyline hydrochloride | Cloperastine hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine |
相關(guān)庫(kù) | FDA上市及藥典收錄分子庫(kù) | 經(jīng)典已知活性庫(kù) | 疼痛相關(guān)化合物庫(kù) | 已知活性化合物庫(kù) | GPCR靶點(diǎn)分子庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:432037-57-5
$210.00 / 1mg
-
-
CAS:189188-57-6
$39.00 / 10mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$15.00/1KG |
|
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-08-11 |
|
$1.00/1g |
VIP5Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2020-05-06 |
|
$7.00/1kg |
VIP7Y
|
Career Henan Chemical Co
|
2018-12-17 |