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Postion:Product Catalog >TCS 21311
TCS 21311
  • TCS 21311

TCS 21311 NEW

Price $99
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-06

Product Details

Product Name: TCS 21311 CAS No.: 1260181-14-3
Purity: ≥98% Supply Ability: 10g
Release date: 2024/11/06

Product Introduction

Bioactivity

名稱TCS 21311
描述TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK2, and TYK2.
體外活性TCS 21311 displays moderate activity in this cellular assay (IC50=689 nM, Jurkat cells), which is in good agreement with its enzymatic Pkc activity. TCS 21311 shows IC50 values of 1.017, 2.550, and 8.055 μM for JAK1, JAK2, and TYK2, respectively?in an enzymatic Jak assay [1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
關(guān)鍵字Protein kinase C | TCS 21311 | Glycogen synthase kinase 3 | TCS21311 | GSK-3 | Glycogen synthase kinase-3 | Inhibitor | JAK | TCS-21311 | inhibit | NIBR-3049 | Janus kinase | NIBR 3049 | PKC
相關(guān)產(chǎn)品Delgocitinib | Cromolyn sodium | Darovasertib | α-Vitamin E | Ruxolitinib | Tofacitinib Citrate | Staurosporine | CHIR-99021 | 4-Chloro-2'-bromoacetophenone | Ruxolitinib phosphate | JAK-IN-10 | GSK-3 Inhibitor 5
相關(guān)庫高選擇性抑制劑庫 | 經(jīng)典已知活性庫 | 抗肥胖化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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