TCS 21311 NEW
Price | $99 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-06 |
Product Details
Product Name: TCS 21311 | CAS No.: 1260181-14-3 |
Purity: ≥98% | Supply Ability: 10g |
Release date: 2024/11/06 |
Product Introduction
Bioactivity
名稱 | TCS 21311 |
描述 | TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK2, and TYK2. |
體外活性 | TCS 21311 displays moderate activity in this cellular assay (IC50=689 nM, Jurkat cells), which is in good agreement with its enzymatic Pkc activity. TCS 21311 shows IC50 values of 1.017, 2.550, and 8.055 μM for JAK1, JAK2, and TYK2, respectively?in an enzymatic Jak assay [1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
關(guān)鍵字 | Protein kinase C | TCS 21311 | Glycogen synthase kinase 3 | TCS21311 | GSK-3 | Glycogen synthase kinase-3 | Inhibitor | JAK | TCS-21311 | inhibit | NIBR-3049 | Janus kinase | NIBR 3049 | PKC |
相關(guān)產(chǎn)品 | Delgocitinib | Cromolyn sodium | Darovasertib | α-Vitamin E | Ruxolitinib | Tofacitinib Citrate | Staurosporine | CHIR-99021 | 4-Chloro-2'-bromoacetophenone | Ruxolitinib phosphate | JAK-IN-10 | GSK-3 Inhibitor 5 |
相關(guān)庫 | 高選擇性抑制劑庫 | 經(jīng)典已知活性庫 | 抗肥胖化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$1980.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
$29.90/1kg |
VIP1Y
|
Yujiang Chemical (Shandong) Co.,Ltd.
|
2024-06-05 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY