Factory Provide Natural Taxus Chinensis Extract Taxol Paclitaxel Powder CAS 33069-62-4

Introduction

Product Name : Paclitaxel 

Other name:  Taxol ; Taxus

CAS No.: 33069-62-4

MF: C47H51NO14

MW: 853.92

Melting Point :213 °C (dec.)(lit.)

Boiling Point :774.66°C (rough estimate)

Appearance: White to off white powder 

Density :0.200g/cm3(Predicted)

Storage :Sealed in dry,Sealed in dry,Room Temperature

Taxol/ Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.

Functions:

1. Paclitaxe is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Paclitaxe has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma. 

Applications: 

1.Taxol is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Taxol has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma.
4.Taxol is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents.