Taraxerol NEW
| Price | $64 | $166 | $266 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Taraxerol | CAS No.: 127-22-0 |
| Purity: 98.92% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Taraxerol |
| Description | Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway. |
| In vitro | Taraxerol (0-100 μM; 24 or 48 hours) significantly reduced cell viability to 95% (20 μM), 89.8% (40 μM), 82.6% (60 μM), 72.9% (80 μM), and 63.6% (100 μM). The cell viability of this compound in HeLa cells at 20 μM and 100 μM concentrations within 48 hours was 90.7% and 53.6%, respectively.[1] Taraxerol (80 μM; 24 or 48 hours) induces apoptosis and cell death in HeLa cells in a dose-dependent manner. Annexin V/PI double staining method showed that compared to the control group’s apoptotic cell count of 6.5% (early stage) and 0.5% (late stage), Taraxerol significantly induced apoptosis to 24.2% (early stage) and 16.2% (late stage).[1] |
| In vivo | Taraxerol (5 and 10 mg/kg; i.p.) reduces carrageenan-induced paw edema. The effect of 5mg/kg Taraxerol was significant (p<0.05) only after 4 hours of carrageenan treatment.[2] |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : <1 mg/mL (Insoluble or slightly soluble) THF : 5 mg/mL (11.72 mM), Sonication is recommended. Methanol : <1 mg/mL (Insoluble or slightly soluble) Ethanol : <1 mg/mL (Insoluble or slightly soluble) H2O : <0.1 mg/ml |
| Keywords | Taraxerol |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Diallyl disulfide |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Terpene Natural Product Library | Bioactive Compound Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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